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Simultaneous LC-MS/MS bioanalysis of alkaloids, terpenoids, and flavonoids in rat plasma through salting-out-assisted liquid-liquid extraction after oral administration of extract from Tetradium ruticarpum and Glycyrrhiza uralensis: a sample preparation strategy to broaden analyte coverage of herbal medicines

Analytical and bioanalytical chemistry, 2021-09, Vol.413 (23), p.5871-5884

2021

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Sinapis Semen: A review on phytochemistry, pharmacology, toxicity, analytical methods and pharmacokinetics

Frontiers in pharmacology, 2023-04, Vol.14, p.1113583-1113583

2023

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Comprehensive Analysis of Serum and Fecal Bile Acid Profiles and Interaction with Gut Microbiota in Primary Biliary Cholangitis

Clinical reviews in allergy & immunology, 2020-02, Vol.58 (1), p.25-38

2020

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Rapid and Simultaneous Quantification of Six Aristolochic Acids and Two Lignans in Asari Radix et Rhizoma Using Ultra-Performance Liquid Chromatography-Triple Quadrupole Tandem Mass Spectrometry

Journal of analytical methods in chemistry, 2022-09, Vol.2022, p.1-9

2022

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Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions

Nature communications, 2023-06, Vol.14 (1), p.3368-3368, Article 3368

2023

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Pharmacokinetic and pharmacodynamic drug-drug interaction of Nomilin with atorvastatin in hyperlipidemic mice

Heliyon, 2023-11, Vol.9 (11), p.e22016-e22016, Article e22016

2023

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Buyang Huanwu Decoction Attenuates Infiltration of Natural Killer Cells and Protects Against Ischemic Brain Injury

Cellular physiology and biochemistry, 2018-01, Vol.50 (4), p.1286-1300

2018

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Metabolic profiling and pharmacokinetic studies of sinapine thiocyanate by UHPLC-Q/TOF-MS and UHPLC-MS/MS

Journal of pharmaceutical and biomedical analysis, 2022-01, Vol.207, p.114431-114431, Article 114431

2022

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Dietary gallic acid as an antioxidant: A review of its food industry applications, health benefits, bioavailability, nano-delivery systems, and drug interactions

Food research international, 2024-03, Vol.180, p.114068-114068, Article 114068

2024

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The in vitro/in vivo metabolic pathways analysis of lobetyol, lobetyolin, and lobetyolinin, three polyacetylenes from Codonopsis Radix, by UHPLC-Q/TOF-MS and UHPLC-MS/MS

Journal of pharmaceutical and biomedical analysis, 2023-01, Vol.223, p.115140-115140, Article 115140

2023

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Characterization of active alkaloids and metabolites in rats after oral administration of Zuojin Pill using UHPLC-Q-TOF-MS combined with bioinformatics and molecular docking analyses

Journal of pharmaceutical and biomedical analysis, 2024-10, Vol.249, p.116340, Article 116340

2024

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Characterization and protein engineering of a novel UDP-glycosyltransferase involved in pseudoginsenoside Rt5 biosynthesis from Panax japonicus

International journal of biological macromolecules, 2024-10, Vol.277 (Pt 4), p.134537, Article 134537

2024

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Rapid identification and pharmacokinetic studies of multiple active alkaloids in rat plasma through UPLC-Q-TOF-MS and UPLC-MS/MS after the oral administration of Zanthoxylum nitidum extract

Journal of pharmaceutical and biomedical analysis, 2020-07, Vol.186, p.113232, Article 113232

2020

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Pharmacokinetic, bioavailability, and metabolism studies of lusianthridin, a dihydrophenanthrene compound, in rats by liquid chromatography/electrospray ionization tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2021-02, Vol.195, p.113836, Article 113836

2021

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Simultaneous determination of cordycepin and its metabolite 3′‐deoxyinosine in rat whole blood by ultra‐high‐performance liquid chromatography coupled with Q Exactive hybrid quadrupole orbitrap high‐resolution accurate mass spectrometry and its application to accurate pharmacokinetic studies

Journal of separation science, 2023-01, Vol.46 (2), p.e2200602-n/a

2023

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The antinociceptive and anti-inflammatory potential and pharmacokinetic study of significant alkamides ingredients from Asarum Linn

Journal of ethnopharmacology, 2022-10, Vol.297, p.115569-115569, Article 115569

2022

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A rapid assay to screen adenosine deaminase inhibitors from Ligustri Lucidi Fructus against metabolism of cordycepin utilizing ultra‐high‐performance liquid chromatography–tandem mass spectrometry

Biomedical chromatography, 2020-03, Vol.34 (3), p.e4779-n/a

2020

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Metabolites identification and reversible interconversion of chelerythrine and dihydrochelerythrine in vitro/in vivo in rats using ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2020-09, Vol.189, p.113462-113462, Article 113462

2020

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Long-term diosbulbin B treatment induced liver fibrosis in mice

Chemico-biological interactions, 2019-01, Vol.298, p.15-23

2019

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Metabolite profiling of Shuganzhi tablets in rats and pharmacokinetics study of four bioactive compounds with liquid chromatography combined with electrospray ionization tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021-08, Vol.1179, p.122827-122827, Article 122827

2021

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Biotransformation patterns of dictamnine in vitro/in vivo and its relative molecular mechanism of dictamnine-induced acute liver injury in mice

Environmental toxicology and pharmacology, 2021-07, Vol.85, p.103628, Article 103628

2021

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Subchronic toxicity and concomitant toxicokinetics of long-term oral administration of total alkaloid extracts from seeds of Peganum harmala Linn: A 28-day study in rats

Journal of ethnopharmacology, 2019-06, Vol.238, p.111866, Article 111866

2019

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Brazilin-Ce nanoparticles attenuate inflammation by de/anti-phosphorylation of IKKβ

Biomaterials, 2024-03, Vol.305, p.122466-122466, Article 122466

2024

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Potential mechanisms of tremor tolerance induced in rats by the repeated administration of total alkaloid extracts from the seeds of Peganum harmala Linn

Journal of ethnopharmacology, 2020-11, Vol.262, p.113183, Article 113183

2020

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Development of Salvianolic acid B–Tanshinone II A–Glycyrrhetinic acid compound liposomes: Formulation optimization and its effects on proliferation of hepatic stellate cells

International journal of pharmaceutics, 2014-02, Vol.462 (1-2), p.11-18

2014

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Sinapis Semen: A review on phytochemistry, pharmacology, toxicity, analytical methods and pharmacokinetics

Comprehensive Analysis of Serum and Fecal Bile Acid Profiles and Interaction with Gut Microbiota in Primary Biliary Cholangitis

Rapid and Simultaneous Quantification of Six Aristolochic Acids and Two Lignans in Asari Radix et Rhizoma Using Ultra-Performance Liquid Chromatography-Triple Quadrupole Tandem Mass Spectrometry

Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions

Pharmacokinetic and pharmacodynamic drug-drug interaction of Nomilin with atorvastatin in hyperlipidemic mice

Buyang Huanwu Decoction Attenuates Infiltration of Natural Killer Cells and Protects Against Ischemic Brain Injury

Metabolic profiling and pharmacokinetic studies of sinapine thiocyanate by UHPLC-Q/TOF-MS and UHPLC-MS/MS

Dietary gallic acid as an antioxidant: A review of its food industry applications, health benefits, bioavailability, nano-delivery systems, and drug interactions

The in vitro/in vivo metabolic pathways analysis of lobetyol, lobetyolin, and lobetyolinin, three polyacetylenes from Codonopsis Radix, by UHPLC-Q/TOF-MS and UHPLC-MS/MS

Characterization of active alkaloids and metabolites in rats after oral administration of Zuojin Pill using UHPLC-Q-TOF-MS combined with bioinformatics and molecular docking analyses

Characterization and protein engineering of a novel UDP-glycosyltransferase involved in pseudoginsenoside Rt5 biosynthesis from Panax japonicus

Rapid identification and pharmacokinetic studies of multiple active alkaloids in rat plasma through UPLC-Q-TOF-MS and UPLC-MS/MS after the oral administration of Zanthoxylum nitidum extract

Pharmacokinetic, bioavailability, and metabolism studies of lusianthridin, a dihydrophenanthrene compound, in rats by liquid chromatography/electrospray ionization tandem mass spectrometry

The antinociceptive and anti-inflammatory potential and pharmacokinetic study of significant alkamides ingredients from Asarum Linn

A rapid assay to screen adenosine deaminase inhibitors from Ligustri Lucidi Fructus against metabolism of cordycepin utilizing ultra‐high‐performance liquid chromatography–tandem mass spectrometry

Metabolites identification and reversible interconversion of chelerythrine and dihydrochelerythrine in vitro/in vivo in rats using ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry

Long-term diosbulbin B treatment induced liver fibrosis in mice

Metabolite profiling of Shuganzhi tablets in rats and pharmacokinetics study of four bioactive compounds with liquid chromatography combined with electrospray ionization tandem mass spectrometry

Biotransformation patterns of dictamnine in vitro/in vivo and its relative molecular mechanism of dictamnine-induced acute liver injury in mice

Subchronic toxicity and concomitant toxicokinetics of long-term oral administration of total alkaloid extracts from seeds of Peganum harmala Linn: A 28-day study in rats

Brazilin-Ce nanoparticles attenuate inflammation by de/anti-phosphorylation of IKKβ

Potential mechanisms of tremor tolerance induced in rats by the repeated administration of total alkaloid extracts from the seeds of Peganum harmala Linn

Development of Salvianolic acid B–Tanshinone II A–Glycyrrhetinic acid compound liposomes: Formulation optimization and its effects on proliferation of hepatic stellate cells

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