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From Worms to Drug Candidate: The Story of Odilorhabdins, a New Class of Antimicrobial Agents

Frontiers in microbiology, 2019-12, Vol.10, p.2893-2893

2019

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The Odilorhabdin Antibiotic Biosynthetic Cluster and Acetyltransferase Self-Resistance Locus Are Niche and Species Specific

mBio, 2022-02, Vol.13 (1), p.e0282621-21

2022

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Resistance to rifampicin: at the crossroads between ecological, genomic and medical concerns

International journal of antimicrobial agents, 2010-06, Vol.35 (6), p.519-523

2010

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Identification of a new antimicrobial lysine-rich cyclolipopeptide family from Xenorhabdus nematophila

Journal of antibiotics, 2009-06, Vol.62 (6), p.295-302

2009

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Type Strains of Entomopathogenic Nematode-Symbiotic Bacterium Species, Xenorhabdus szentirmaii (EMC) and X. budapestensis (EMA), Are Exceptional Sources of Non-Ribosomal Templated, Large-Target-Spectral, Thermotolerant-Antimicrobial Peptides (by Both), and Iodinin (by EMC)

Pathogens (Basel), 2022-03, Vol.11 (3), p.342

2022

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Cabanillasin, a new antifungal metabolite, produced by entomopathogenic Xenorhabdus cabanillasii JM26

Journal of antibiotics, 2013-10, Vol.66 (10), p.617-620

2013

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In Vitro Activities of Different Inhibitors of Bacterial Transcription against Staphylococcus epidermidis Biofilm

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3117-3121

2007

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Novel synthetic molecules targeting the bacterial RNA polymerase assembly

Journal of antimicrobial chemotherapy, 2006-02, Vol.57 (2), p.245-251

2006

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The antibiotics in the chemical space

Current medicinal chemistry, 2009, Vol.16 (3), p.390-393

2009

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Use of a Surface Plasmon Resonance Method To Investigate Antibiotic and Plasma Protein Interactions

Antimicrobial Agents and Chemotherapy, 2009-04, Vol.53 (4), p.1528-1531

2009

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Exploring Cluster-Dependent Antibacterial Activities and Resistance Pathways of NOSO-502 and Colistin against Enterobacter cloacae Complex Species

Antimicrobial agents and chemotherapy, 2022-11, Vol.66 (11), p.e0077622-e0077622

2022

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Missense Mutations in the CrrB Protein Mediate Odilorhabdin Derivative Resistance in Klebsiella pneumoniae

Antimicrobial agents and chemotherapy, 2021-04, Vol.65 (5)

2021

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The AcrAB efflux pump confers self-resistance to stilbenes in Photorhabdus laumondii

Research in microbiology, 2023-09, Vol.174 (7), p.104081-104081, Article 104081

2023

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The transcription inhibitor lipiarmycin blocks DNA fitting into the RNA polymerase catalytic site

The EMBO journal, 2010-08, Vol.29 (15), p.2527-2537

2010

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In Vitro and In Vivo Characterization of NOSO-502, a Novel Inhibitor of Bacterial Translation

Antimicrobial agents and chemotherapy, 2018-09, Vol.62 (9)

2018

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Total Synthesis and Structure–Activity Relationships Study of Odilorhabdins, a New Class of Peptides Showing Potent Antibacterial Activity

Journal of medicinal chemistry, 2018-09, Vol.61 (17), p.7814-7826

2018

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Structure-activity relationship studies on the inhibition of the bacterial translation of novel Odilorhabdins analogues

Bioorganic & medicinal chemistry, 2020-06, Vol.28 (11), p.115469-115469, Article 115469

2020

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Progress in targeting bacterial transcription

Drug discovery today, 2007-03, Vol.12 (5), p.200-208

2007

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In vitro activity of a new antibacterial rhodanine derivative against Staphylococcus epidermidis biofilms

Journal of antimicrobial chemotherapy, 2006-10, Vol.58 (4), p.778-783

2006

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Structure−Activity Relationships of Phenyl-Furanyl-Rhodanines as Inhibitors of RNA Polymerase with Antibacterial Activity on Biofilms

Journal of medicinal chemistry, 2007-08, Vol.50 (17), p.4195-4204

2007

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Frequency and characterisation of spontaneous lipiarmycin-resistant Enterococcus faecalis mutants selected in vitro

International journal of antimicrobial agents, 2009-12, Vol.34 (6), p.605-606

2009

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Draft Genome Sequence and Annotation of the Entomopathogenic Bacterium Xenorhabdus szentirmaii Strain DSM16338

Genome announcements (Washington, DC), 2014-03, Vol.2 (2)

2014

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Resistance to rifampicin: at the crossroads between ecological, genomic and medical concerns

International journal of antimicrobial agents, 2010-04, Vol.35 (6)

2010

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Myxopyronin: a punch in the jaws of bacterial RNA polymerase

Future microbiology, 2009-03, Vol.4 (2), p.145-149

2009

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From Worms to Drug Candidate: The Story of Odilorhabdins, a New Class of Antimicrobial Agents

The Odilorhabdin Antibiotic Biosynthetic Cluster and Acetyltransferase Self-Resistance Locus Are Niche and Species Specific

Resistance to rifampicin: at the crossroads between ecological, genomic and medical concerns

Identification of a new antimicrobial lysine-rich cyclolipopeptide family from Xenorhabdus nematophila

Type Strains of Entomopathogenic Nematode-Symbiotic Bacterium Species, Xenorhabdus szentirmaii (EMC) and X. budapestensis (EMA), Are Exceptional Sources of Non-Ribosomal Templated, Large-Target-Spectral, Thermotolerant-Antimicrobial Peptides (by Both), and Iodinin (by EMC)

Cabanillasin, a new antifungal metabolite, produced by entomopathogenic Xenorhabdus cabanillasii JM26

In Vitro Activities of Different Inhibitors of Bacterial Transcription against Staphylococcus epidermidis Biofilm

Novel synthetic molecules targeting the bacterial RNA polymerase assembly

The antibiotics in the chemical space

Use of a Surface Plasmon Resonance Method To Investigate Antibiotic and Plasma Protein Interactions

Exploring Cluster-Dependent Antibacterial Activities and Resistance Pathways of NOSO-502 and Colistin against Enterobacter cloacae Complex Species

Missense Mutations in the CrrB Protein Mediate Odilorhabdin Derivative Resistance in Klebsiella pneumoniae

The AcrAB efflux pump confers self-resistance to stilbenes in Photorhabdus laumondii

Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site

The transcription inhibitor lipiarmycin blocks DNA fitting into the RNA polymerase catalytic site

In Vitro and In Vivo Characterization of NOSO-502, a Novel Inhibitor of Bacterial Translation

Total Synthesis and Structure–Activity Relationships Study of Odilorhabdins, a New Class of Peptides Showing Potent Antibacterial Activity

Structure-activity relationship studies on the inhibition of the bacterial translation of novel Odilorhabdins analogues

Progress in targeting bacterial transcription

In vitro activity of a new antibacterial rhodanine derivative against Staphylococcus epidermidis biofilms

Structure−Activity Relationships of Phenyl-Furanyl-Rhodanines as Inhibitors of RNA Polymerase with Antibacterial Activity on Biofilms

Frequency and characterisation of spontaneous lipiarmycin-resistant Enterococcus faecalis mutants selected in vitro

Draft Genome Sequence and Annotation of the Entomopathogenic Bacterium Xenorhabdus szentirmaii Strain DSM16338

Resistance to rifampicin: at the crossroads between ecological, genomic and medical concerns

Myxopyronin: a punch in the jaws of bacterial RNA polymerase

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