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Relapse after CAR-T cell therapy in B-cell malignancies: challenges and future approaches

Journal of Zhejiang University. B. Science, 2022-10, Vol.23 (10), p.793-811

2022

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Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway

Cell reports (Cambridge), 2024-04, Vol.43 (4), p.114065-114065, Article 114065

2024

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Daratumumab Prevents Experimental Xenogeneic Graft-Versus-Host Disease by Skewing Proportions of T Cell Functional Subsets and Inhibiting T Cell Activation and Migration

Frontiers in immunology, 2021-12, Vol.12, p.785774-785774

2021

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Novel cellular immunotherapies for hematological malignancies: recent updates from the 2021 ASH annual meeting

Experimental hematology & oncology, 2022-09, Vol.11 (1), p.1-61, Article 61

2022

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Inhibition of Calcium Signaling Prevents Exhaustion and Enhances Anti‐Leukemia Efficacy of CAR‐T Cells via SOCE‐Calcineurin‐NFAT and Glycolysis Pathways

Advanced science, 2022-03, Vol.9 (9), p.e2103508-n/a

2022

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How can we improve the successful identification of patients suitable for CAR-T cell therapy?

Expert review of molecular diagnostics, 2024-09, Vol.24 (9), p.777-792

2024

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Hematologic cytopenia post CAR T cell therapy: Etiology, potential mechanisms and perspective

Cancer letters, 2022-12, Vol.550, p.215920-215920, Article 215920

2022

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Mitochondrial Isocitrate Dehydrogenase Inhibition Enhances CAR T-Cell Function By Restraining Antioxidant Metabolism and Histone Acetylation

Blood, 2023-11, Vol.142 (Supplement 1), p.3451-3451

2023

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Epigenetic Reprogramming By Histone Deacetylase Inhibitors Improves CAR-T Cell Functions

Blood, 2023-11, Vol.142 (Supplement 1), p.2080-2080

2023

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KLF9 suppresses gastric cancer cell invasion and metastasis through transcriptional inhibition of MMP28

The FASEB journal, 2019-07, Vol.33 (7), p.7915-7928

2019

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Central Nervous System Relapse after CAR-T Cell Therapy in B-Cell Malignancies

Blood, 2022-11, Vol.140 (Supplement 1), p.13220-13221

2022

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Hydrogel-based microenvironment engineering of haematopoietic stem cells

Cellular and molecular life sciences : CMLS, 2023-02, Vol.80 (2), p.49-49, Article 49

2023

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How can we improve the successful identification of patients suitable for CAR-T cell therapy?

Expert review of molecular diagnostics, 2024-09, p.1

2024

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Mechanisms of immune effector cell‐associated neurotoxicity syndrome after CAR‐T treatment

Wiley interdisciplinary reviews. Mechanisms of disease, 2022-11, Vol.14 (6), p.e1576-n/a

2022

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Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation

Cell metabolism, 2024-01, Vol.36 (1), p.176-192.e10

2024

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Characteristics of Central Nervous System Relapse after CD19 CAR-T Cell Therapy in R/R NHL

Blood, 2023-11, Vol.142 (Supplement 1), p.6915-6915

2023

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Sequential CD7 CAR T-Cell Therapy and Allogeneic HSCT without GVHD Prophylaxis

The New England journal of medicine, 2024-04, Vol.390 (16), p.1467-1480

2024

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Neither Conditioning Chemotherapy Nor GvHD-Prophylaxis: CD7 CAR-T Treatment Bridging to Haplo-HSCT

Blood, 2023-11, Vol.142 (Supplement 1), p.1039-1039

2023

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A Multi-Omic Single-Cell Landscape of Cytokine Release Syndrome in Multiple Myeloma Patients after Anti-BCMA CAR-T Cell Therapy

Blood, 2023-11, Vol.142 (Supplement 1), p.101-101

2023

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CAR T-cell therapies in China: rapid evolution and a bright future

The Lancet. Haematology, 2022-12, Vol.9 (12), p.e930-e941

2022

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MEK Inhibition in CAR-T Cells Prevents Exhaustion and Terminal Differentiation Via Downregulating C-Fos and JunB

Blood, 2022-11, Vol.140 (Supplement 1), p.626-627

2022

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MEK inhibition prevents CAR-T cell exhaustion and differentiation via downregulation of c-Fos and JunB

Signal transduction and targeted therapy, 2024-10, Vol.9 (1), p.293, Article 293

2024

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Targeting the metabolism of tumor-infiltrating regulatory T cells

Trends in immunology, 2023-08, Vol.44 (8), p.598-612

2023

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Precise Mixed-Criticality Scheduling on Varying-Speed Multiprocessors

IEEE transactions on computers, 2023-01, Vol.72 (1), p.43-54

2023

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Lactate supports Treg function and immune balance via MGAT1 effects on N-glycosylation in the mitochondria

The Journal of clinical investigation, 2024-09, Vol.134 (20)

2024

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Relapse after CAR-T cell therapy in B-cell malignancies: challenges and future approaches

Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway

Daratumumab Prevents Experimental Xenogeneic Graft-Versus-Host Disease by Skewing Proportions of T Cell Functional Subsets and Inhibiting T Cell Activation and Migration

Novel cellular immunotherapies for hematological malignancies: recent updates from the 2021 ASH annual meeting

Inhibition of Calcium Signaling Prevents Exhaustion and Enhances Anti‐Leukemia Efficacy of CAR‐T Cells via SOCE‐Calcineurin‐NFAT and Glycolysis Pathways

How can we improve the successful identification of patients suitable for CAR-T cell therapy?

Hematologic cytopenia post CAR T cell therapy: Etiology, potential mechanisms and perspective

Mitochondrial Isocitrate Dehydrogenase Inhibition Enhances CAR T-Cell Function By Restraining Antioxidant Metabolism and Histone Acetylation

Epigenetic Reprogramming By Histone Deacetylase Inhibitors Improves CAR-T Cell Functions

KLF9 suppresses gastric cancer cell invasion and metastasis through transcriptional inhibition of MMP28

Central Nervous System Relapse after CAR-T Cell Therapy in B-Cell Malignancies

Hydrogel-based microenvironment engineering of haematopoietic stem cells

How can we improve the successful identification of patients suitable for CAR-T cell therapy?

Mechanisms of immune effector cell‐associated neurotoxicity syndrome after CAR‐T treatment

Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation

Characteristics of Central Nervous System Relapse after CD19 CAR-T Cell Therapy in R/R NHL

Sequential CD7 CAR T-Cell Therapy and Allogeneic HSCT without GVHD Prophylaxis

Neither Conditioning Chemotherapy Nor GvHD-Prophylaxis: CD7 CAR-T Treatment Bridging to Haplo-HSCT

A Multi-Omic Single-Cell Landscape of Cytokine Release Syndrome in Multiple Myeloma Patients after Anti-BCMA CAR-T Cell Therapy

CAR T-cell therapies in China: rapid evolution and a bright future

MEK Inhibition in CAR-T Cells Prevents Exhaustion and Terminal Differentiation Via Downregulating C-Fos and JunB

MEK inhibition prevents CAR-T cell exhaustion and differentiation via downregulation of c-Fos and JunB

Targeting the metabolism of tumor-infiltrating regulatory T cells

Precise Mixed-Criticality Scheduling on Varying-Speed Multiprocessors

Lactate supports Treg function and immune balance via MGAT1 effects on N-glycosylation in the mitochondria

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