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Unraveling Triple-Negative Breast Cancer Tumor Microenvironment Heterogeneity: Towards an Optimized Treatment Approach

JNCI : Journal of the National Cancer Institute, 2020-07, Vol.112 (7), p.708-719

2020

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Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers

The Journal of clinical investigation, 2019-04, Vol.129 (4), p.1785-1800

2019

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miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response

Nature medicine, 2011-12, Vol.17 (12), p.1627-1635

2011

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Identification of Interacting Stromal Axes in Triple-Negative Breast Cancer

Cancer research (Chicago, Ill.), 2017-09, Vol.77 (17), p.4673-4683

2017

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KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer

Cell reports (Cambridge), 2018-03, Vol.22 (12), p.3191-3205

2018

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CrosstalkNet: A Visualization Tool for Differential Co-expression Networks and Communities

Cancer research (Chicago, Ill.), 2018-04, Vol.78 (8), p.2140-2143

2018

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Predicting Relapse in Patients With Triple Negative Breast Cancer (TNBC) Using a Deep-Learning Approach

Frontiers in physiology, 2020-09, Vol.11, p.511071-511071

2020

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Infiltration of CD8⁺ T cells into tumor cell clusters in triple-negative breast cancer

Proceedings of the National Academy of Sciences - PNAS, 2019-02, Vol.116 (9), p.3678-3687

2019

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Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients

EMBO molecular medicine, 2016-05, Vol.8 (5), p.527-549

2016

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Abstract 6710: AVID200, a first-in-class selective TGF-beta 1 and -beta 3 inhibitor, sensitizes tumors to immune checkpoint blockade therapies

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6710-6710

2020

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MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas

Nature communications, 2015-10, Vol.6 (1), p.8583-8583, Article 8583

2015

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Abstract B65: Mathematical modeling studies on spatial profiles of tumor-infiltrating T cells

Cancer immunology research, 2020-04, Vol.8 (4_Supplement), p.B65-B65

2020

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Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss

Cancer research (Chicago, Ill.), 2018-10, Vol.78 (19), p.5618-5630

2018

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Abstract PO-080: Predicting relapse in patients with triple negative breast cancer (TNBC) using a deep-learning approach

Cancer research (Chicago, Ill.), 2020-11, Vol.80 (21_Supplement), p.PO-080-PO-080

2020

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AVID200, first-in-class TGF-beta 1 and 3 selective and potent inhibitor: Safety and biomarker results of a phase I monotherapy dose-escalation study in patients with advanced solid tumors

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.3587-3587

2020

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Elevated V-ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer

Molecular cancer research, 2020-10, Vol.18 (10), p.1477-1490

2020

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Abstract IA23: Deconvolution of the triple-negative breast cancer microenvironment

Cancer research (Chicago, Ill.), 2016-08, Vol.76 (15_Supplement), p.IA23-IA23

2016

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Abstract 720: Novel prognostic stromal subtypes in triple-negative breast cancer

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.720-720

2016

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Abstract A15: Mechanisms of CD8+ T cell immunosuppression in triple negative breast cancer

Cancer research (Chicago, Ill.), 2016-08, Vol.76 (15_Supplement), p.A15-A15

2016

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Abstract LB-200: Loss of the scaffold protein Kibra in a mouse model of triple-negative breast cancer

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.LB-200-LB-200

2015

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Abstract P4-04-01: A new breast cancer classification scheme based on novel classes of tumor stroma

Cancer research (Chicago, Ill.), 2015-05, Vol.75 (9_Supplement), p.P4-P4-04-01

2015

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The Human Adenovirus Type 5 E4orf4 Protein Targets Two Phosphatase Regulators of the Hippo Signaling Pathway

Journal of virology, 2015-09, Vol.89 (17), p.8855-8870

2015

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P856 AVID200, first-in-class TGF-beta1 and beta3 selective inhibitor: results of a phase 1 monotherapy dose escalation study in solid tumors and evidence of target engagement in patients

Journal for immunotherapy of cancer, 2020-04, Vol.8 (Suppl 1), p.A6-A7

2020

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Unraveling Triple-Negative Breast Cancer Tumor Microenvironment Heterogeneity: Towards an Optimized Treatment Approach

Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers

Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression

miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response

HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin

Identification of Interacting Stromal Axes in Triple-Negative Breast Cancer

KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer

CrosstalkNet: A Visualization Tool for Differential Co-expression Networks and Communities

Predicting Relapse in Patients With Triple Negative Breast Cancer (TNBC) Using a Deep-Learning Approach

Infiltration of CD8⁺ T cells into tumor cell clusters in triple-negative breast cancer

Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients

Abstract 6710: AVID200, a first-in-class selective TGF-beta 1 and -beta 3 inhibitor, sensitizes tumors to immune checkpoint blockade therapies

MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas

Abstract B65: Mathematical modeling studies on spatial profiles of tumor-infiltrating T cells

Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss

Abstract PO-080: Predicting relapse in patients with triple negative breast cancer (TNBC) using a deep-learning approach

AVID200, first-in-class TGF-beta 1 and 3 selective and potent inhibitor: Safety and biomarker results of a phase I monotherapy dose-escalation study in patients with advanced solid tumors

Elevated V-ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer

Abstract IA23: Deconvolution of the triple-negative breast cancer microenvironment

Abstract 720: Novel prognostic stromal subtypes in triple-negative breast cancer

Abstract A15: Mechanisms of CD8+ T cell immunosuppression in triple negative breast cancer

Abstract LB-200: Loss of the scaffold protein Kibra in a mouse model of triple-negative breast cancer

Abstract P4-04-01: A new breast cancer classification scheme based on novel classes of tumor stroma

The Human Adenovirus Type 5 E4orf4 Protein Targets Two Phosphatase Regulators of the Hippo Signaling Pathway

P856 AVID200, first-in-class TGF-beta1 and beta3 selective inhibitor: results of a phase 1 monotherapy dose escalation study in solid tumors and evidence of target engagement in patients

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