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To fight tuberculosis, fund basic research

PLoS biology, 2018-09, Vol.16 (9), p.e3000037-e3000037

Grundner, Christoph

2018

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The Mycobacterium tuberculosis PE15/PPE20 complex transports calcium across the outer membrane

PLoS biology, 2022-11, Vol.20 (11), p.e3001906-e3001906

2022

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More than two components: complexities in bacterial phosphosignaling

mSystems, 2024-05, Vol.9 (5), p.e0028924-e0028924

2024

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Mycobacterium tuberculosis supports protein tyrosine phosphorylation

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (25), p.9265-9270

2014

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Mycobacterium tuberculosis Ser/Thr protein kinase B mediates an oxygen-dependent replication switch

PLoS biology, 2014-01, Vol.12 (1), p.e1001746-e1001746

2014

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A Cas12a-based CRISPR interference system for multigene regulation in mycobacteria

The Journal of biological chemistry, 2021-08, Vol.297 (2), p.100990-100990, Article 100990

2021

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Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (52), p.E5069-E5077

2013

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Access of Antibody Molecules to the Conserved Coreceptor Binding Site on Glycoprotein gp120 Is Sterically Restricted on Primary Human Immunodeficiency Virus Type 1

Journal of Virology, 2003-10, Vol.77 (19), p.10557-10565

2003

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A Global Survey of ATPase Activity in Plasmodium falciparum Asexual Blood Stages and Gametocytes

Molecular & cellular proteomics, 2018-01, Vol.17 (1), p.111-120

2018

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Regulatory Intersection of Two-component System and Ser/Thr Protein Kinase Signaling in Mycobacterium tuberculosis

Journal of molecular biology, 2024-01, Vol.436 (2), p.168379, Article 168379

2024

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Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis

Nature microbiology, 2021-01, Vol.6 (1), p.44-50

2021

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Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB Structure Reveals a Diverged Fold and a Buried Active Site

Structure (London), 2005-11, Vol.13 (11), p.1625-1634

2005

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Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB

Structure (London), 2007-04, Vol.15 (4), p.499-509

2007

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Structure and Substrate Recognition of the Staphylococcus aureus Protein Tyrosine Phosphatase PtpA

Journal of molecular biology, 2011-10, Vol.413 (1), p.24-31

2011

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Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpB

Organic & biomolecular chemistry, 2010-09, Vol.8 (18), p.4066-4070

2010

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Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition

Virology (New York, N.Y.), 2003-09, Vol.313 (2), p.387-400

2003

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Tyrosine Sulfation of Human Antibodies Contributes to Recognition of the CCR5 Binding Region of HIV-1 gp120

Cell, 2003-07, Vol.114 (2), p.161-170

2003

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Solid-Phase Proteoliposomes Containing Human Immunodeficiency Virus Envelope Glycoproteins

Journal of Virology, 2002-04, Vol.76 (7), p.3511-3521

2002

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Activity-based annotation: the emergence of systems biochemistry

Trends in biochemical sciences (Amsterdam. Regular ed.), 2022-09, Vol.47 (9), p.785-794

2022

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Agents of change – concepts in M ycobacterium tuberculosis Ser / Thr / Tyr phosphosignalling

Molecular microbiology, 2014-10, Vol.94 (2), p.231-241

2014

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Agents of change – concepts in Mycobacterium tuberculosis Ser/Thr/Tyr phosphosignalling

Molecular microbiology, 2014-10, Vol.94 (2), p.231-241

2014

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Dual Inhibition of Mycobacterium tuberculosis and the Host TGFBR1 by an Anilinoquinazoline

Journal of medicinal chemistry, 2023-11, Vol.66 (21), p.14724-14734

2023

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Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines

Bioorganic & medicinal chemistry letters, 2019-09, Vol.29 (18), p.2695-2699

2019

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Systematic Survey of Serine Hydrolase Activity in Mycobacterium tuberculosis Defines Changes Associated with Persistence

Cell chemical biology, 2016-02, Vol.23 (2), p.290-298

2016

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Mycobacterium tuberculosis Rv3651 is a triple sensor-domain protein: Mycobacterium Tuberculosis Rv3651

Protein science, 2017-12, Vol.27 (2)

2017

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To fight tuberculosis, fund basic research

The Mycobacterium tuberculosis PE15/PPE20 complex transports calcium across the outer membrane

More than two components: complexities in bacterial phosphosignaling

Mycobacterium tuberculosis supports protein tyrosine phosphorylation

Mycobacterium tuberculosis Ser/Thr protein kinase B mediates an oxygen-dependent replication switch

A Cas12a-based CRISPR interference system for multigene regulation in mycobacteria

Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase

Access of Antibody Molecules to the Conserved Coreceptor Binding Site on Glycoprotein gp120 Is Sterically Restricted on Primary Human Immunodeficiency Virus Type 1

A Global Survey of ATPase Activity in Plasmodium falciparum Asexual Blood Stages and Gametocytes

Regulatory Intersection of Two-component System and Ser/Thr Protein Kinase Signaling in Mycobacterium tuberculosis

Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis

Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB Structure Reveals a Diverged Fold and a Buried Active Site

Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB

Structure and Substrate Recognition of the Staphylococcus aureus Protein Tyrosine Phosphatase PtpA

Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpB

Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition

Tyrosine Sulfation of Human Antibodies Contributes to Recognition of the CCR5 Binding Region of HIV-1 gp120

Solid-Phase Proteoliposomes Containing Human Immunodeficiency Virus Envelope Glycoproteins

Activity-based annotation: the emergence of systems biochemistry

Agents of change – concepts in M ycobacterium tuberculosis Ser / Thr / Tyr phosphosignalling

Agents of change – concepts in Mycobacterium tuberculosis Ser/Thr/Tyr phosphosignalling

Dual Inhibition of Mycobacterium tuberculosis and the Host TGFBR1 by an Anilinoquinazoline

Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines

Systematic Survey of Serine Hydrolase Activity in Mycobacterium tuberculosis Defines Changes Associated with Persistence

Mycobacterium tuberculosis Rv3651 is a triple sensor-domain protein: Mycobacterium Tuberculosis Rv3651

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