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Physiology of invertebrate oxytocin and vasopressin neuropeptides

Experimental physiology, 2014-01, Vol.99 (1), p.55-61

Gruber, Christian W.

2014

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Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors

Current pharmaceutical design, 2010-01, Vol.16 (28), p.3071-3088

2010

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Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis

Proceedings of the National Academy of Sciences - PNAS, 2016-04, Vol.113 (15), p.3960-3965

2016

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Discovery of defense- and neuropeptides in social ants by genome-mining

PloS one, 2012-03, Vol.7 (3), p.e32559-e32559

2012

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Isolation and functional diversity of Bowman-Birk type serine proteinase inhibitors from Hyacinthus orientalis

Biochemical journal, 2021-03, Vol.478 (6), p.1287-1301

2021

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Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (52), p.21183-21188

2013

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Peptide-based protease inhibitors from plants

Drug discovery today, 2019-09, Vol.24 (9), p.1877-1889

2019

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Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor

Nature communications, 2023-12, Vol.14 (1), p.8064-8064, Article 8064

2023

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Molecular Grafting onto a Stable Framework Yields Novel Cyclic Peptides for the Treatment of Multiple Sclerosis

ACS chemical biology, 2014-01, Vol.9 (1), p.156-163

2014

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In vitro Inhibition of HIV-1 by Cyclotide-Enriched Extracts of Viola tricolor

Frontiers in pharmacology, 2022-05, Vol.13, p.888961-888961

2022

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Insights into the molecular evolution of oxytocin receptor ligand binding

Biochemical Society transactions, 2013-02, Vol.41 (1), p.197-204

2013

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Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism

PloS one, 2013-06, Vol.8 (6), p.e68016

2013

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Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (12), p.3227-3232

2016

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MALDI TOF/TOF-Based Approach for the Identification of d- Amino Acids in Biologically Active Peptides and Proteins

Journal of proteome research, 2016-05, Vol.15 (5), p.1487-1496

2016

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Plant-Derived Peptides: (Neglected) Natural Products for Drug Discovery

Planta medica, 2024-06, Vol.90 (7-08), p.627

Gruber, Christian W

2024

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Discovery of the cyclotide caripe 11 as a ligand of the cholecystokinin-2 receptor

Scientific reports, 2022-06, Vol.12 (1), p.9215-10, Article 9215

2022

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Design, synthesis, conformational analysis, and biological activity of Cα1-to-Cα6 1,4- and 4,1-disubstituted 1H-[1,2,3]triazol-1-yl-bridged oxytocin analogues

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2254019-2254019

2023

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Ipecac root extracts and isolated circular peptides differentially suppress inflammatory immune response characterised by proliferation, activation and degranulation capacity of human lymphocytes in vitro

Biomedicine & pharmacotherapy, 2022-08, Vol.152, p.113120-113120, Article 113120

2022

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Cyclotides Isolated From Violet Plants of Cameroon Are Inhibitors of Human Prolyl Oligopeptidase

Frontiers in pharmacology, 2021-07, Vol.12, p.707596-707596

2021

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Distribution and Evolution of Circular Miniproteins in Flowering Plants

The Plant cell, 2008-09, Vol.20 (9), p.2471-2483

2008

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The nature inspired peptide [T20K]-kalata B1 induces anti-tumor effects in anaplastic large cell lymphoma

Biomedicine & pharmacotherapy, 2022-09, Vol.153, p.113486-113486, Article 113486

2022

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Oxytocin‐like signaling in ants influences metabolic gene expression and locomotor activity

The FASEB journal, 2018-12, Vol.32 (12), p.6808-6821

2018

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Cyclotides Isolated from an Ipecac Root Extract Antagonize the Corticotropin Releasing Factor Type 1 Receptor

Frontiers in pharmacology, 2017-09, Vol.8, p.616

2017

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Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum

Journal of natural products (Washington, D.C.), 2015-05, Vol.78 (5), p.1073-1082

2015

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Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide

Scientific reports, 2017-02, Vol.7 (1), p.41002, Article 41002

2017

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Physiology of invertebrate oxytocin and vasopressin neuropeptides

Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors

Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis

Discovery of defense- and neuropeptides in social ants by genome-mining

Isolation and functional diversity of Bowman-Birk type serine proteinase inhibitors from Hyacinthus orientalis

Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design

Peptide-based protease inhibitors from plants

Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor

Molecular Grafting onto a Stable Framework Yields Novel Cyclic Peptides for the Treatment of Multiple Sclerosis

In vitro Inhibition of HIV-1 by Cyclotide-Enriched Extracts of Viola tricolor

Insights into the molecular evolution of oxytocin receptor ligand binding

Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism

Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides

MALDI TOF/TOF-Based Approach for the Identification of d- Amino Acids in Biologically Active Peptides and Proteins

Plant-Derived Peptides: (Neglected) Natural Products for Drug Discovery

Discovery of the cyclotide caripe 11 as a ligand of the cholecystokinin-2 receptor

Design, synthesis, conformational analysis, and biological activity of Cα1-to-Cα6 1,4- and 4,1-disubstituted 1H-[1,2,3]triazol-1-yl-bridged oxytocin analogues

Ipecac root extracts and isolated circular peptides differentially suppress inflammatory immune response characterised by proliferation, activation and degranulation capacity of human lymphocytes in vitro

Cyclotides Isolated From Violet Plants of Cameroon Are Inhibitors of Human Prolyl Oligopeptidase

Distribution and Evolution of Circular Miniproteins in Flowering Plants

The nature inspired peptide [T20K]-kalata B1 induces anti-tumor effects in anaplastic large cell lymphoma

Oxytocin‐like signaling in ants influences metabolic gene expression and locomotor activity

Cyclotides Isolated from an Ipecac Root Extract Antagonize the Corticotropin Releasing Factor Type 1 Receptor

Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum

Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide

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