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Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction

PLoS genetics, 2023-01, Vol.19 (1), p.e1010565-e1010565

2023

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Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains

PLoS pathogens, 2015-06, Vol.11 (6), p.e1004983-e1004983

2015

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Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

Acta neuropathologica communications, 2018-02, Vol.6 (1), p.7-7, Article 7

2018

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Prions and the Potential Transmissibility of Protein Misfolding Diseases

Annual review of microbiology, 2013-01, Vol.67 (1), p.543-564

2013

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Rapid and sensitive RT-QuIC detection of human Creutzfeldt-Jakob disease using cerebrospinal fluid

mBio, 2015-01, Vol.6 (1)

2015

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Cerebral organoids as a new model for prion disease

PLoS pathogens, 2021-07, Vol.17 (7), p.e1009747-e1009747

2021

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Efficacy of Wex-cide 128 disinfectant against multiple prion strains

PloS one, 2023-08, Vol.18 (8), p.e0290325-e0290325

2023

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The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases

Nature protocols, 2016-11, Vol.11 (11), p.2233-2242

2016

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Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt-Jakob disease

Scientific reports, 2021-03, Vol.11 (1), p.5165-5165, Article 5165

2021

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Stress and viral insults do not trigger E200K PrP conversion in human cerebral organoids

PloS one, 2022-10, Vol.17 (10), p.e0277051-e0277051

2022

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Role of the central lysine cluster and scrapie templating in the transmissibility of synthetic prion protein aggregates

PLoS pathogens, 2017-09, Vol.13 (9), p.e1006623-e1006623

2017

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Reduced SOD2 expression does not influence prion disease course or pathology in mice

PloS one, 2021-11, Vol.16 (11), p.e0259597-e0259597

2021

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High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease

Acta neuropathologica communications, 2021-11, Vol.9 (1), p.179-13, Article 179

2021

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Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid

PLoS pathogens, 2016-09, Vol.12 (9), p.e1005914-e1005914

2016

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α-Synuclein seeding activity in duodenum biopsies from Parkinson's disease patients

PLoS pathogens, 2023-06, Vol.19 (6), p.e1011456-e1011456

2023

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Using our mini-brains: cerebral organoids as an improved cellular model for human prion disease

Neural regeneration research, 2020-06, Vol.15 (6), p.1019-1020

2020

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Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids

Acta neuropathologica communications, 2019-06, Vol.7 (1), p.90-90, Article 90

2019

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Hereditary E200K mutation within the prion protein gene alters human iPSC derived cardiomyocyte function

Scientific reports, 2022-09, Vol.12 (1), p.15788-15788, Article 15788

2022

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Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces

PLoS pathogens, 2024-04, Vol.20 (4), p.e1012175-e1012175

2024

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Detection of Atypical H-Type Bovine Spongiform Encephalopathy and Discrimination of Bovine Prion Strains by Real-Time Quaking-Induced Conversion

Journal of clinical microbiology, 2016-03, Vol.54 (3), p.676-686

2016

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Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease

Acta neuropathologica communications, 2022-06, Vol.10 (1), p.90-90, Article 90

2022

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RT-QuIC Assays for Prion Disease Detection and Diagnostics

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1658, p.185

2017

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Factors That Improve RT-QuIC Detection of Prion Seeding Activity

Viruses, 2016-05, Vol.8 (5), p.140

2016

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Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity

PLoS pathogens, 2017-07, Vol.13 (7), p.e1006491-e1006491

2017

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Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction

Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains

Diagnosis of Human Prion Disease Using Real-Time Quaking-Induced Conversion Testing of Olfactory Mucosa and Cerebrospinal Fluid Samples

Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

Prions and the Potential Transmissibility of Protein Misfolding Diseases

Rapid and sensitive RT-QuIC detection of human Creutzfeldt-Jakob disease using cerebrospinal fluid

Cerebral organoids as a new model for prion disease

Efficacy of Wex-cide 128 disinfectant against multiple prion strains

The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases

Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt-Jakob disease

Stress and viral insults do not trigger E200K PrP conversion in human cerebral organoids

Role of the central lysine cluster and scrapie templating in the transmissibility of synthetic prion protein aggregates

Reduced SOD2 expression does not influence prion disease course or pathology in mice

High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease

Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid

α-Synuclein seeding activity in duodenum biopsies from Parkinson's disease patients

Using our mini-brains: cerebral organoids as an improved cellular model for human prion disease

Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids

Hereditary E200K mutation within the prion protein gene alters human iPSC derived cardiomyocyte function

Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces

Detection of Atypical H-Type Bovine Spongiform Encephalopathy and Discrimination of Bovine Prion Strains by Real-Time Quaking-Induced Conversion

Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease

RT-QuIC Assays for Prion Disease Detection and Diagnostics

Factors That Improve RT-QuIC Detection of Prion Seeding Activity

Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity

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