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Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study

Human gene therapy, 1993-12, Vol.4 (6), p.771-780

1993

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Long-Term Improvement of Hypercholesterolemia After ex Vivo Gene Therapy in LDLR-Deficient Rabbits

Science (American Association for the Advancement of Science), 1991-12, Vol.254 (5039), p.1802-1805

1991

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Safety and feasibility of liver- directed ex vivo gene therapy for homozygous familial hypercholesterolemia

Annals of surgery, 1996-02, Vol.223 (2), p.116-126

1996

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A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia

Nature medicine, 1995-11, Vol.1 (11), p.1148-1154

1995

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Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia

Nature genetics, 1994-04, Vol.6 (4), p.335-341

1994

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A Controlled Study of Adenoviral-Vector–Mediated Gene Transfer in the Nasal Epithelium of Patients with Cystic Fibrosis

The New England journal of medicine, 1995-09, Vol.333 (13), p.823-831

1995

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Gene Therapy of Cystic Fibrosis Lung Disease Using E1 Deleted Adenoviruses: A Phase I Trial. University of Michigan, Ann Arbor, Michigan and University of Pennsylvania, Philadelphia, Pennsylvania

Human gene therapy, 1994-04, Vol.5 (4), p.501-519

1994

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Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats

The Journal of biological chemistry, 1991-08, Vol.266 (22), p.14338-14342

1991

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The low density lipoprotein receptor is not required for normal catabolism of Lp(a) in humans

The Journal of clinical investigation, 1995-03, Vol.95 (3), p.1403-1408

1995

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Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: biological efficacy study

Human gene therapy, 1993-12, Vol.4 (6), p.759-769

1993

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Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits

The Journal of biological chemistry, 1992-01, Vol.267 (2), p.963-967

1992

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Transplantation of genetically modified autologous hepatocytes into nonhuman primates: feasibility and short-term toxicity

Human gene therapy, 1992-10, Vol.3 (5), p.501-510

1992

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Temporary Amelioration of Hyperlipidemia in Low Density Lipoprotein Receptor-Deficient Rabbits Transplanted with Genetically Modified Hepatocytes

Proceedings of the National Academy of Sciences - PNAS, 1990-11, Vol.87 (21), p.8437-8441

1990

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Ex Vivo Gene Therapy of Familial Hypercholesterolemia. Howard Hughes Medical Institute, University of Michigan

Human gene therapy, 1992-04, Vol.3 (2), p.179-222

1992

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Gene therapy of cystic fibrosis lung disease using E1 deleted adenoviruses: a phase I trial

Human gene therapy, 1994-04, Vol.5 (4), p.501-519

1994

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A novel mechanism for achieving transgene persistence in vivo after somatic gene transfer into hepatocytes

The Journal of biological chemistry, 1992-06, Vol.267 (16), p.11483-11489

1992

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Expression of Human Adenosine Deaminase in Mice Reconstituted with Retrovirus-Transduced Hematopoietic Stem Cells

Proceedings of the National Academy of Sciences - PNAS, 1990-01, Vol.87 (1), p.439-443

1990

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Retroviruses: delivery vehicle to the liver

Current opinion in genetics & development, 1993-02, Vol.3 (1), p.110-114

1993

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Therapeutic strategies for familial hypercholesterolemia based on somatic gene transfer

The American journal of cardiology, 1993-09, Vol.72 (10), p.D59-D63

1993

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Adenovirus-mediated correction of the genetic defect in hepatocytes from patients with familial hypercholesterolemia

Somatic cell and molecular genetics, 1993-09, Vol.19 (5), p.449-458

1993

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Retroviral-mediated gene transfer in human hepatocytes

Surgery, 1992-08, Vol.112 (2), p.333

1992

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Gene Therapy for Cystic Fibrosis Using E1-Deleted Adenovirus: A Phase I Trial in the Nasal Cavity. University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

Human gene therapy, 1994-05, Vol.5 (5), p.615-639

1994

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Towards liver-directed gene therapy : retrovirus-mediated gene transfer into human hepatocytes

Somatic cell and molecular genetics, 1991-11, Vol.17 (6), p.601-607

1991

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Somatic gene transfer in the development of an animal model for primary hyperparathyroidism

Endocrinology (Philadelphia), 1992-05, Vol.130 (5), p.2947-2954

1992

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A novel approach for introducing hepatocytes into the portal circulation

The Journal of laboratory and clinical medicine, 1993-03, Vol.121 (3), p.472

1993

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Biological And Medical Sciences
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Male
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Genetic Therapy - Methods
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Liver - Cytology
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Adult
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Genetic Vectors
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Receptors, Ldl - Genetics
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Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study

Long-Term Improvement of Hypercholesterolemia After ex Vivo Gene Therapy in LDLR-Deficient Rabbits

Safety and feasibility of liver- directed ex vivo gene therapy for homozygous familial hypercholesterolemia

A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia

Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia

A Controlled Study of Adenoviral-Vector–Mediated Gene Transfer in the Nasal Epithelium of Patients with Cystic Fibrosis

Gene Therapy of Cystic Fibrosis Lung Disease Using E1 Deleted Adenoviruses: A Phase I Trial. University of Michigan, Ann Arbor, Michigan and University of Pennsylvania, Philadelphia, Pennsylvania

Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats

The low density lipoprotein receptor is not required for normal catabolism of Lp(a) in humans

Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: biological efficacy study

Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits

Transplantation of genetically modified autologous hepatocytes into nonhuman primates: feasibility and short-term toxicity

Temporary Amelioration of Hyperlipidemia in Low Density Lipoprotein Receptor-Deficient Rabbits Transplanted with Genetically Modified Hepatocytes

Ex Vivo Gene Therapy of Familial Hypercholesterolemia. Howard Hughes Medical Institute, University of Michigan

Gene therapy of cystic fibrosis lung disease using E1 deleted adenoviruses: a phase I trial

A novel mechanism for achieving transgene persistence in vivo after somatic gene transfer into hepatocytes

Expression of Human Adenosine Deaminase in Mice Reconstituted with Retrovirus-Transduced Hematopoietic Stem Cells

Retroviruses: delivery vehicle to the liver

Therapeutic strategies for familial hypercholesterolemia based on somatic gene transfer

Adenovirus-mediated correction of the genetic defect in hepatocytes from patients with familial hypercholesterolemia

Retroviral-mediated gene transfer in human hepatocytes

Gene Therapy for Cystic Fibrosis Using E1-Deleted Adenovirus: A Phase I Trial in the Nasal Cavity. University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

Towards liver-directed gene therapy : retrovirus-mediated gene transfer into human hepatocytes

Somatic gene transfer in the development of an animal model for primary hyperparathyroidism

A novel approach for introducing hepatocytes into the portal circulation

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