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High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor

PloS one, 2016-09, Vol.11 (9), p.e0163129

2016

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Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease

PloS one, 2015-06, Vol.10 (6), p.e0131071-e0131071

2015

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Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates

BMC immunology, 2012-10, Vol.13 (1), p.57-57, Article 57

2012

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Human α3β4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells

PloS one, 2010-10, Vol.5 (10), p.e13611-e13611

2010

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High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function

PloS one, 2014-06, Vol.9 (6), p.e97973

2014

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Single‐channel study of the spasmodic mutation α1A52S in recombinant rat glycine receptors

The Journal of physiology, 2007-05, Vol.581 (1), p.51-73

2007

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Human alpha 3 beta 4 Neuronal Nicotinic Receptors Show Different Stoichiometry if They Are Expressed in Xenopus Oocytes or Mammalian HEK293 Cells

PloS one, 2010-10, Vol.5

2010

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Constraining the Expression of Nicotinic Acetylcholine Receptors by Using Pentameric Constructs

Molecular pharmacology, 2006-02, Vol.69 (2), p.558-563

2006

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Single-Channel Behavior of Heteromeric α1β Glycine Receptors: An Attempt to Detect a Conformational Change before the Channel Opens

The Journal of neuroscience, 2004-12, Vol.24 (48), p.10924-10940

2004

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Cholinergic drugs potentiate human nicotinic α4β2 acetylcholine receptors by a competitive mechanism

European journal of pharmacology, 2005-02, Vol.509 (2), p.97-108

2005

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Variomics Screen Identifies the Re-entrant Loop of the Calcium-activated Chloride Channel ANO1 That Facilitates Channel Activation

The Journal of biological chemistry, 2015-01, Vol.290 (2), p.889-903

2015

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Single-channel study of the spasmodic mutation alpha 1A52S in recombinant rat glycine receptors

The Journal of physiology, 2007-05, Vol.581 (1), p.51-73

2007

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Incorporation of the beta 3 Subunit Has a Dominant-Negative Effect on the Function of Recombinant Central-Type Neuronal Nicotinic Receptors

Molecular pharmacology, 2006-10, Vol.70 (4), p.1350-1357

2006

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Incorporation of the β3 Subunit Has a Dominant-Negative Effect on the Function of Recombinant Central-Type Neuronal Nicotinic Receptors

Molecular pharmacology, 2006-10, Vol.70 (4), p.1350-1357

2006

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The development of automated patch clamp assays for canonical transient receptor potential channels TRPC3, 6, and 7

Assay and drug development technologies, 2014-06, Vol.12 (5), p.282

2014

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Formation of functional α3β4α5 human neuronal nicotinic receptors in Xenopus oocytes: a reporter mutation approach

British journal of pharmacology, 2001-10, Vol.134 (4), p.789-796

2001

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Stoichiometry of recombinant heteromeric glycine receptors revealed by a pore-lining region point mutation

Receptors & channels, 2003, Vol.9 (6), p.353

2003

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Openings of the Rat Recombinant α1 Homomeric Glycine Receptor as a Function of the Number of Agonist Molecules Bound

The Journal of general physiology, 2002-05, Vol.119 (5), p.443-466

2002

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Incomplete incorporation of tandem subunits in recombinant neuronal nicotinic receptors

The Journal of general physiology, 2004-06, Vol.123 (6), p.697-708

2004

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Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of α1 glycine receptors in HEK293 cells

Journal of neuroscience methods, 2002, Vol.113 (2), p.207-214

2002

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Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits β3 and β4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32

FEBS letters, 1997-01, Vol.400 (3), p.309-314

1997

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Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules bound

The Journal of general physiology, 2002-05, Vol.119 (5), p.443

2002

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Muscle Nicotinic Acetylcholine Receptors containing α1‐V275 or α1‐Y233 Mutants found in a functional Screen reveal enhanced Agonist Potencies

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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The Activation Mechanism of α1 Homomeric Glycine Receptors

The Journal of neuroscience, 2004-01, Vol.24 (4), p.895-906

2004

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Development of TRPC Assays on Automated Electrophysiology Platforms

Biophysical journal, 2014-01, Vol.106 (2), p.753a-753a

2014

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High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor

Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease

Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates

Human α3β4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells

High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function

Single‐channel study of the spasmodic mutation α1A52S in recombinant rat glycine receptors

Human alpha 3 beta 4 Neuronal Nicotinic Receptors Show Different Stoichiometry if They Are Expressed in Xenopus Oocytes or Mammalian HEK293 Cells

Constraining the Expression of Nicotinic Acetylcholine Receptors by Using Pentameric Constructs

Single-Channel Behavior of Heteromeric α1β Glycine Receptors: An Attempt to Detect a Conformational Change before the Channel Opens

Cholinergic drugs potentiate human nicotinic α4β2 acetylcholine receptors by a competitive mechanism

Variomics Screen Identifies the Re-entrant Loop of the Calcium-activated Chloride Channel ANO1 That Facilitates Channel Activation

Single-channel study of the spasmodic mutation alpha 1A52S in recombinant rat glycine receptors

Incorporation of the beta 3 Subunit Has a Dominant-Negative Effect on the Function of Recombinant Central-Type Neuronal Nicotinic Receptors

Incorporation of the β3 Subunit Has a Dominant-Negative Effect on the Function of Recombinant Central-Type Neuronal Nicotinic Receptors

The development of automated patch clamp assays for canonical transient receptor potential channels TRPC3, 6, and 7

Formation of functional α3β4α5 human neuronal nicotinic receptors in Xenopus oocytes: a reporter mutation approach

Stoichiometry of recombinant heteromeric glycine receptors revealed by a pore-lining region point mutation

Openings of the Rat Recombinant α1 Homomeric Glycine Receptor as a Function of the Number of Agonist Molecules Bound

Incomplete incorporation of tandem subunits in recombinant neuronal nicotinic receptors

Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of α1 glycine receptors in HEK293 cells

Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits β3 and β4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32

Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules bound

Muscle Nicotinic Acetylcholine Receptors containing α1‐V275 or α1‐Y233 Mutants found in a functional Screen reveal enhanced Agonist Potencies

The Activation Mechanism of α1 Homomeric Glycine Receptors

Development of TRPC Assays on Automated Electrophysiology Platforms

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