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Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine- Directed Therapies

Annual review of medicine, 2015-01, Vol.66 (1), p.145-159

2015

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Macrophage activation syndrome in the era of biologic therapy

Nature reviews. Rheumatology, 2016-05, Vol.12 (5), p.259

2016

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On the Alert for Cytokine Storm: Immunopathology in COVID‐19

Arthritis & rheumatology (Hoboken, N.J.), 2020-07, Vol.72 (7), p.1059-1063

2020

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Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome

Blood, 2018-03, Vol.131 (13), p.1442-1455

2018

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Macrophage activation syndrome and cytokine-directed therapies

Best practice & research. Clinical rheumatology, 2014-04, Vol.28 (2), p.277-292

2014

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IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome

Rheumatology (Oxford, England), 2020-02, Vol.59 (2), p.361-366

2020

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Whole‐Exome Sequencing Reveals Overlap Between Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis and Familial Hemophagocytic Lymphohistiocytosis

Arthritis & rheumatology (Hoboken, N.J.), 2014-12, Vol.66 (12), p.3486-3495

2014

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Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

The Journal of infectious diseases, 2016-04, Vol.213 (7), p.1180-1188

2016

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The 4th NextGen therapies for SJIA and MAS: part 3 clinical trials in refractory SJIA: historic controls as an alternative to a withdrawal design study

Pediatric rheumatology online journal, 2024-01, Vol.21 (Suppl 1), p.150-150, Article 150

2024

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Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis

The Journal of clinical investigation, 2023-11, Vol.133 (22), p.1-18

2023

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Urine S100 proteins as potential biomarkers of lupus nephritis activity

Arthritis research & therapy, 2017-10, Vol.19 (1), p.242-242, Article 242

2017

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Neutrophils From Children With Systemic Juvenile Idiopathic Arthritis Exhibit Persistent Proinflammatory Activation Despite Long-Standing Clinically Inactive Disease

Frontiers in immunology, 2018-12, Vol.9, p.2995-2995

2018

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The 4th NextGen therapies for SJIA and MAS: part 2 phenotypes of refractory SJIA and the landscape for clinical trials in refractory SJIA

Pediatric rheumatology online journal, 2024-01, Vol.21 (Suppl 1), p.87-87, Article 87

2024

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Genetic Defects in Cytolysis in Macrophage Activation Syndrome

Current rheumatology reports, 2014-09, Vol.16 (9), p.439-439, Article 439

2014

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Systemic JIA: new developments in the understanding of the pathophysiology and therapy

Best practice & research. Clinical rheumatology, 2009-10, Vol.23 (5), p.655-664

2009

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The use of S100 proteins testing in juvenile idiopathic arthritis and autoinflammatory diseases in a pediatric clinical setting: a retrospective analysis

Pediatric rheumatology online journal, 2020-01, Vol.18 (1), p.7-7, Article 7

2020

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Follistatin-like protein 1 and the ferritin/erythrocyte sedimentation rate ratio are potential biomarkers for dysregulated gene expression and macrophage activation syndrome in systemic juvenile idiopathic arthritis

Journal of rheumatology, 2013-07, Vol.40 (7), p.1191

2013

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Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities?

Current opinion in rheumatology, 2003-09, Vol.15 (5), p.587-590

Grom, Alexei A

2003

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IFN-γ is essential for alveolar macrophage-driven pulmonary inflammation in macrophage activation syndrome

JCI insight, 2021-09, Vol.6 (17)

2021

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Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome

Arthritis research & therapy, 2005-01, Vol.7 (1), p.R30-R37

2005

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Part 5: Allogeneic HSCT in refractory SJIA with lung disease; recent cases from centers in North America & Europe

Pediatric rheumatology online journal, 2024-01, Vol.21 (Suppl 1), p.86-86, Article 86

2024

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Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions

Nature reviews. Rheumatology, 2011-07, Vol.7 (7), p.416

2011

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Proceedings from the 4th NextGen Therapies for SJIA and MAS virtual symposium held February 13–14, 2022

Pediatric rheumatology online journal, 2024-01, Vol.21 (Suppl 1), p.91-91, Article 91

2024

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Update on the pathogenesis and treatment of systemic idiopathic arthritis

Current opinion in pediatrics, 2011-12, Vol.23 (6), p.640-646

2011

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Reasons for canakinumab initiation among patients with periodic fever syndromes: a retrospective medical chart review from the United States

Pediatric rheumatology online journal, 2021-09, Vol.19 (1), p.143-143, Article 143

2021

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Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine- Directed Therapies

Macrophage activation syndrome in the era of biologic therapy

On the Alert for Cytokine Storm: Immunopathology in COVID‐19

Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome

Macrophage activation syndrome and cytokine-directed therapies

IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome

Whole‐Exome Sequencing Reveals Overlap Between Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis and Familial Hemophagocytic Lymphohistiocytosis

Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

The 4th NextGen therapies for SJIA and MAS: part 3 clinical trials in refractory SJIA: historic controls as an alternative to a withdrawal design study

Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis

Urine S100 proteins as potential biomarkers of lupus nephritis activity

Neutrophils From Children With Systemic Juvenile Idiopathic Arthritis Exhibit Persistent Proinflammatory Activation Despite Long-Standing Clinically Inactive Disease

The 4th NextGen therapies for SJIA and MAS: part 2 phenotypes of refractory SJIA and the landscape for clinical trials in refractory SJIA

Genetic Defects in Cytolysis in Macrophage Activation Syndrome

Systemic JIA: new developments in the understanding of the pathophysiology and therapy

The use of S100 proteins testing in juvenile idiopathic arthritis and autoinflammatory diseases in a pediatric clinical setting: a retrospective analysis

Follistatin-like protein 1 and the ferritin/erythrocyte sedimentation rate ratio are potential biomarkers for dysregulated gene expression and macrophage activation syndrome in systemic juvenile idiopathic arthritis

Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities?

IFN-γ is essential for alveolar macrophage-driven pulmonary inflammation in macrophage activation syndrome

Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome

Part 5: Allogeneic HSCT in refractory SJIA with lung disease; recent cases from centers in North America & Europe

Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions

Proceedings from the 4th NextGen Therapies for SJIA and MAS virtual symposium held February 13–14, 2022

Update on the pathogenesis and treatment of systemic idiopathic arthritis

Reasons for canakinumab initiation among patients with periodic fever syndromes: a retrospective medical chart review from the United States

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