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Dual-targeting class I HDAC inhibitor and ATM activator, SP-1-303, preferentially inhibits estrogen receptor positive breast cancer cell growth

PloS one, 2024-07, Vol.19 (7), p.e0306168

2024

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Fluorescent Epigenetic Small Molecule Induces Expression of the Tumor Suppressor Ras-Association Domain Family 1A and Inhibits Human Prostate Xenograft

Journal of medicinal chemistry, 2010-03, Vol.53 (6), p.2376-2382

2010

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Synthesis and biological evaluation of a fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain and imaging agent

Bioorganic & medicinal chemistry, 2012-09, Vol.20 (17), p.5269-5276

2012

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Fluorescent cyclin-dependent kinase inhibitors block the proliferation of human breast cancer cells

Bioorganic & medicinal chemistry, 2011-04, Vol.19 (8), p.2714-2725

2011

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18Oxygen Substituted Nucleosides Combined with Proton Beam Therapy: Therapeutic Transmutation In Vitro

International journal of particle therapy, 2021-03, Vol.7 (4), p.11-18

2021

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Meso-Substituted [34]Octaphyrin(1.1.1.0.1.1.1.0) and Corrole Formation in Reactions of a Dipyrromethanedicarbinol with 2,2‘-Bipyrrole

Journal of organic chemistry, 2004-09, Vol.69 (19), p.6404-6412

2004

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Abstract A15: DNA damage response-targeted molecules for breast cancer therapy

Molecular cancer research, 2018-08, Vol.16 (8_Supplement), p.A15-A15

2018

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Abstract A178: Targeting the ATM-mediated DNA damage response pathway for cancer treatment

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.A178-A178

2018

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Abstract 4054: Development of dual function small molecules as therapeutic agents for cancer treatment

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.4054-4054

2017

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Abstract PO-060: Blood based metabolomic biomarker assay to predict radiation late effects in prostate cancer patients

Clinical cancer research, 2021-04, Vol.27 (8_Supplement), p.PO-060-PO-060

2021

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VMY-1-103, a dansylated analog of purvalanol B, induces caspase-3-dependent apoptosis in LNCaP prostate cancer cells

Cancer biology & therapy, 2010-08, Vol.10 (4), p.320-325

2010

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Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition

Molecular cancer therapeutics, 2023-12, Vol.22 (12), p.1376-1389

2023

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Radiotherapy Induces Innate Immune Responses in Patients Treated for Prostate Cancers

Clinical cancer research, 2023-03, Vol.29 (5), p.921-929

2023

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Abstract PO-007: 18O-substituted nucleosides combined with proton beam: “Theranostic transformation.”

Clinical cancer research, 2021-04, Vol.27 (8_Supplement), p.PO-007-PO-007

2021

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Abstract 3215: Therapeutic potential of dual-function small molecules for breast cancers

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3215-3215

2017

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Abstract 5855: Radiosensitization of cervical cancer cells by HDAC inhibitors

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5855-5855

2017

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Asymmetric Synthesis of 2,3-Dihydro-2-arylquinazolin-4-ones: Methodology and Application to a Potent Fluorescent Tubulin Inhibitor with Anticancer Activity

Journal of medicinal chemistry, 2008-08, Vol.51 (15), p.4620-4631

2008

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Abstract A013: Selective HDAC6 inhibition by SP-2-225 enhances the innate anti-tumor immune response after radiation exposure

Cancer research (Chicago, Ill.), 2024-01, Vol.84 (1_Supplement), p.A013-A013

2024

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Abstract A005: Enhanced DNA damage and disruption of repair by iodinated thymidine analogues with Tipiracil for clinical radiation sensitization

Cancer research (Chicago, Ill.), 2024-01, Vol.84 (1_Supplement), p.A005-A005

2024

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Novel Carbazole Inhibits Phospho-STAT3 through Induction of Protein–Tyrosine Phosphatase PTPN6

Journal of medicinal chemistry, 2014-08, Vol.57 (15), p.6342-6353

2014

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Abstract PO023: Immune-mediated tumor growth inhibition by selective HDAC6 inhibitor SP-2-225

Cancer immunology research, 2021-02, Vol.9 (2_Supplement), p.PO023-PO023

2021

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Abstract 1122: Inhibition of HDAC6 enhanced radiation therapy induced antitumor response in melanoma

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.1122-1122

2024

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MP35-11 METABOLIC BIOMARKERS ARE PREDICTIVE OF RESPONSE TO RADIATION THERAPY IN PROSTATE CANCER PATIENTS

The Journal of urology, 2018-04, Vol.199 (4), p.e451-e451

2018

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Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients

Cancer research communications, 2022-12, Vol.2 (12), p.1617-1625

2022

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Discovery of Metabolic Biomarkers Predicting Radiation Therapy Late Effects in Prostate Cancer Patients

Advances in experimental medicine and biology, 2019, Vol.1164, p.141-150

2019

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Dual-targeting class I HDAC inhibitor and ATM activator, SP-1-303, preferentially inhibits estrogen receptor positive breast cancer cell growth

Fluorescent Epigenetic Small Molecule Induces Expression of the Tumor Suppressor Ras-Association Domain Family 1A and Inhibits Human Prostate Xenograft

Synthesis and biological evaluation of a fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain and imaging agent

Fluorescent cyclin-dependent kinase inhibitors block the proliferation of human breast cancer cells

18Oxygen Substituted Nucleosides Combined with Proton Beam Therapy: Therapeutic Transmutation In Vitro

Meso-Substituted [34]Octaphyrin(1.1.1.0.1.1.1.0) and Corrole Formation in Reactions of a Dipyrromethanedicarbinol with 2,2‘-Bipyrrole

Abstract A15: DNA damage response-targeted molecules for breast cancer therapy

Abstract A178: Targeting the ATM-mediated DNA damage response pathway for cancer treatment

Abstract 4054: Development of dual function small molecules as therapeutic agents for cancer treatment

Abstract PO-060: Blood based metabolomic biomarker assay to predict radiation late effects in prostate cancer patients

VMY-1-103, a dansylated analog of purvalanol B, induces caspase-3-dependent apoptosis in LNCaP prostate cancer cells

Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition

Radiotherapy Induces Innate Immune Responses in Patients Treated for Prostate Cancers

Abstract PO-007: 18O-substituted nucleosides combined with proton beam: “Theranostic transformation.”

Abstract 3215: Therapeutic potential of dual-function small molecules for breast cancers

Abstract 5855: Radiosensitization of cervical cancer cells by HDAC inhibitors

Asymmetric Synthesis of 2,3-Dihydro-2-arylquinazolin-4-ones: Methodology and Application to a Potent Fluorescent Tubulin Inhibitor with Anticancer Activity

Abstract A013: Selective HDAC6 inhibition by SP-2-225 enhances the innate anti-tumor immune response after radiation exposure

Abstract A005: Enhanced DNA damage and disruption of repair by iodinated thymidine analogues with Tipiracil for clinical radiation sensitization

Novel Carbazole Inhibits Phospho-STAT3 through Induction of Protein–Tyrosine Phosphatase PTPN6

Abstract PO023: Immune-mediated tumor growth inhibition by selective HDAC6 inhibitor SP-2-225

Abstract 1122: Inhibition of HDAC6 enhanced radiation therapy induced antitumor response in melanoma

MP35-11 METABOLIC BIOMARKERS ARE PREDICTIVE OF RESPONSE TO RADIATION THERAPY IN PROSTATE CANCER PATIENTS

Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients

Discovery of Metabolic Biomarkers Predicting Radiation Therapy Late Effects in Prostate Cancer Patients

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