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The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia

Oncogene, 2018-01, Vol.37 (4), p.450-460

2018

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Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner

Leukemia, 2016-02, Vol.30 (2), p.508-513

2016

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The Binding of the PDZ Tandem of Syntenin to Target Proteins

Biochemistry (Easton), 2006-03, Vol.45 (11), p.3674-3683

2006

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Discovery of novel menin-MLL small molecule inhibitors that display high potency and selectivity in vitro and in vivo

European journal of cancer (1990), 2016-12, Vol.69, p.S88-S88

2016

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A phosphonamidate containing aromatic N-terminal amino group as inhibitor of leucine aminopeptidase—design, synthesis and stability

European journal of medicinal chemistry, 2006-06, Vol.41 (6), p.768-772

2006

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Leucine aminopeptidase as a target for inhibitor design

Mini reviews in medicinal chemistry, 2001-07, Vol.1 (2), p.133-144

2001

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The Most Potent Organophosphorus Inhibitors of Leucine Aminopeptidase. Structure-Based Design, Chemistry, and Activity

Journal of medicinal chemistry, 2003-06, Vol.46 (13), p.2641-2655

2003

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Structure of Bacillus subtilis YXKO—A member of the UPF0031 family and a putative kinase

Journal of structural biology, 2002-09, Vol.139 (3), p.161-170

2002

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Ab initio study of the physical nature of interactions between enzyme active site fragments in vacuo

PCCP. Physical chemistry chemical physics (Print), 2001, Vol.3 (5), p.657-663

2001

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High resolution structure of the HDGF PWWP domain: A potential DNA binding domain

Protein science, 2006-02, Vol.15 (2), p.314-323

2006

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Non-empirical analysis of the nature of the inhibitor–active-site interactions in leucine aminopeptidase

Chemical physics letters, 1999-11, Vol.313 (1-2), p.385-392

1999

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Computer-aided design and activity prediction of leucine aminopeptidase inhibitors

Journal of computer-aided molecular design, 2000-08, Vol.14 (6), p.531-544

2000

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Quantum chemical analysis of the interactions of transition state analogs with leucine aminopeptidase

International journal of quantum chemistry, 2001, Vol.84 (2), p.302-310

2001

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Electrostatic models of inhibitory activity

International journal of quantum chemistry, 2001, Vol.83 (3-4), p.180-192

2001

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α-Aminoalkylphosphonates as a tool in experimental optimisation of P1 side chain shape of potential inhibitors in S1 pocket of leucine- and neutral aminopeptidases

European journal of medicinal chemistry, 2005-08, Vol.40 (8), p.764-771

2005

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Hydrolysis of the Phosphonamidate Bond in Phosphono Dipeptide Analogues - the Influence of the Nature of the N-Terminal Functional Group

European journal of organic chemistry, 2003-12, Vol.2003 (24), p.4797-4803

2003

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Origins of the Activity of PAL and LAP Enzyme Inhibitors: Toward Ab Initio Binding Affinity Prediction

Journal of the American Chemical Society, 2005-02, Vol.127 (6), p.1658-1659

2005

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Herbicidal derivatives of aminomethylenebisphosphonic acid. Part III. Structure-activity relationship

Journal of plant growth regulation, 1997-08, Vol.16 (3), p.153-158

1997

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Exploring the Sn Binding Pockets in Gingipains by Newly Developed Inhibitors: Structure-Based Design, Chemistry, and Activity

Journal of medicinal chemistry, 2006-03, Vol.49 (5), p.1744-1753

2006

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A Mutation in the S-switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for CBFβ Regulation

Journal of molecular biology, 2006-12, Vol.364 (5), p.1073-1083

2006

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Development of Allosteric Inhibitors of the Interaction of AML1 and CBFβ for the Treatment of Leukemia

Blood, 2007-11, Vol.110 (11), p.653-653

2007

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The Computer-Aided Design, Synthesis, and Activity Prediction of New Leucine Aminopeptidase Inhibitors

Phosphorus, sulfur, and silicon and the related elements, 2002-06, Vol.177 (6-7), p.1591-1595

2002

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Structure-Based Design and Synthesis of Dipeptide Analogues as New Inhibitors of Leucine Aminopeptidase

Phosphorus, sulfur, and silicon and the related elements, 2002-06, Vol.177 (6-7), p.1739-1743

2002

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Structure of Bacillus subtilis YXKO - a member of UPF0031 - a putative kinase

Journal of structural biology, 2002-09, Vol.139 (3 ; Sep. 2002)

2002

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The usage of database techniques to evaluate the structural genomics targets

Acta crystallographica. Section A, Foundations of crystallography, 2002-08, Vol.58 (s1), p.c368-c368

2002

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The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia

Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner

The Binding of the PDZ Tandem of Syntenin to Target Proteins

Discovery of novel menin-MLL small molecule inhibitors that display high potency and selectivity in vitro and in vivo

A phosphonamidate containing aromatic N-terminal amino group as inhibitor of leucine aminopeptidase—design, synthesis and stability

Leucine aminopeptidase as a target for inhibitor design

The Most Potent Organophosphorus Inhibitors of Leucine Aminopeptidase. Structure-Based Design, Chemistry, and Activity

Structure of Bacillus subtilis YXKO—A member of the UPF0031 family and a putative kinase

Ab initio study of the physical nature of interactions between enzyme active site fragments in vacuo

High resolution structure of the HDGF PWWP domain: A potential DNA binding domain

Non-empirical analysis of the nature of the inhibitor–active-site interactions in leucine aminopeptidase

Computer-aided design and activity prediction of leucine aminopeptidase inhibitors

Quantum chemical analysis of the interactions of transition state analogs with leucine aminopeptidase

Electrostatic models of inhibitory activity

α-Aminoalkylphosphonates as a tool in experimental optimisation of P1 side chain shape of potential inhibitors in S1 pocket of leucine- and neutral aminopeptidases

Hydrolysis of the Phosphonamidate Bond in Phosphono Dipeptide Analogues - the Influence of the Nature of the N-Terminal Functional Group

Origins of the Activity of PAL and LAP Enzyme Inhibitors: Toward Ab Initio Binding Affinity Prediction

Herbicidal derivatives of aminomethylenebisphosphonic acid. Part III. Structure-activity relationship

Exploring the Sn Binding Pockets in Gingipains by Newly Developed Inhibitors: Structure-Based Design, Chemistry, and Activity

A Mutation in the S-switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for CBFβ Regulation

Development of Allosteric Inhibitors of the Interaction of AML1 and CBFβ for the Treatment of Leukemia

The Computer-Aided Design, Synthesis, and Activity Prediction of New Leucine Aminopeptidase Inhibitors

Structure-Based Design and Synthesis of Dipeptide Analogues as New Inhibitors of Leucine Aminopeptidase

Structure of Bacillus subtilis YXKO - a member of UPF0031 - a putative kinase

The usage of database techniques to evaluate the structural genomics targets

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