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Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma

Cell, 2019-10, Vol.179 (4), p.829-845.e20

2019

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Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with combined SOS1 and MEK Inhibition for Improved Immunotherapy Response

Cancer research communications, 2024-06, Vol.4 (6), p.1548-1560

2024

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Discovery and Characterization of a Substrate Selective p38α Inhibitor

Biochemistry (Easton), 2004-09, Vol.43 (37), p.11658-11671

2004

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The discovery of carboline analogs as potent MAPKAP-K2 inhibitors

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (16), p.4664-4669

2007

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Inhibition of pro-inflammatory cytokine production by the dual p38/JNK2 inhibitor BIRB796 correlates with the inhibition of p38 signaling

Biochemical pharmacology, 2009-02, Vol.77 (3), p.422-432

2009

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The discovery of thienopyridine analogues as potent IκB kinase β inhibitors. Part II

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (19), p.5547-5551

2009

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The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function

American journal of clinical and experimental immunology, 2013-01, Vol.2 (2), p.172-185

2013

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Catalysis and Function of the p38α·MK2a Signaling Complex

Biochemistry (Easton), 2004-08, Vol.43 (31), p.9950-9960

2004

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Thermal Denaturation: A Method to Rank Slow Binding, High-Affinity P38α MAP Kinase Inhibitors

Journal of medicinal chemistry, 2003-10, Vol.46 (22), p.4669-4675

2003

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Discovery of 2-Phenylamino-imidazo[4,5-h]isoquinolin-9-ones: A New Class of Inhibitors of Lck Kinase

Journal of medicinal chemistry, 2002-08, Vol.45 (16), p.3394-3405

2002

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Bioluminescent method for assaying multiple semicarbazide-sensitive amine oxidase (SSAO) family members in both 96- and 384-well formats

Journal of biomolecular screening, 2011-10, Vol.16 (9), p.1106-1111

2011

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Optimization of 2-Phenylaminoimidazo[4,5-h]isoquinolin-9-ones: Orally Active Inhibitors of lck Kinase

Journal of medicinal chemistry, 2003-04, Vol.46 (8), p.1337-1349

2003

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IKKα, IKKβ, and NEMO/IKKγ Are Each Required for the NF-κB-mediated Inflammatory Response Program

The Journal of biological chemistry, 2002-11, Vol.277 (47), p.45129-45140

2002

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The kinetics of binding to p38MAP kinase by analogues of BIRB 796

Bioorganic & medicinal chemistry letters, 2003-09, Vol.13 (18), p.3101-3104

2003

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Novel NEMO/IκB Kinase and NF-κB Target Genes at the Pre-B to Immature B Cell Transition

The Journal of biological chemistry, 2001-05, Vol.276 (21), p.18579-18590

2001

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IκB Kinases α and β Show a Random Sequential Kinetic Mechanism and Are Inhibited by Staurosporine and Quercetin

The Journal of biological chemistry, 1999-11, Vol.274 (46), p.32655-32661

1999

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The kinetics of binding to p38 MAP kinase by analogues of BIRB 796

Bioorganic & medicinal chemistry letters, 2003, Vol.13 (18), p.3101-3104

2003

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Non-Sialate Inhibitor of Influenza A/WSN/33 Neuraminidase

Biochemistry (Easton), 1995-05, Vol.34 (21), p.7154-7160

1995

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Recombinant IκB Kinases α and β Are Direct Kinases of IκBα

The Journal of biological chemistry, 1998-11, Vol.273 (46), p.30736-30741

1998

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The discovery of thienopyridine analogues as potent I[kappa]B kinase beta inhibitors. Part II

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (19), p.5547-5551

2009

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IÎºB Kinases Î± and Î² Show a Random Sequential Kinetic Mechanism and Are Inhibited by Staurosporine and Quercetin

The Journal of biological chemistry, 1999-11, Vol.274 (46), p.32655

1999

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Catalysis and function of the p38 alpha.MK2a signaling complex

Biochemistry (Easton), 2004-08, Vol.43 (31), p.9950-9960

2004

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Thermal denaturation: a method to rank slow binding, high-affinity P38alpha MAP kinase inhibitors

Journal of medicinal chemistry, 2003-10, Vol.46 (22), p.4669-4675

2003

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Discovery and characterization of a substrate selective p38alpha inhibitor

Biochemistry (Easton), 2004-09, Vol.43 (37), p.11658-11671

2004

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IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program

The Journal of biological chemistry, 2002-11, Vol.277 (47), p.45129-45140

2002

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Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma

Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with combined SOS1 and MEK Inhibition for Improved Immunotherapy Response

Discovery and Characterization of a Substrate Selective p38α Inhibitor

The discovery of carboline analogs as potent MAPKAP-K2 inhibitors

Inhibition of pro-inflammatory cytokine production by the dual p38/JNK2 inhibitor BIRB796 correlates with the inhibition of p38 signaling

The discovery of thienopyridine analogues as potent IκB kinase β inhibitors. Part II

The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function

Catalysis and Function of the p38α·MK2a Signaling Complex

Thermal Denaturation: A Method to Rank Slow Binding, High-Affinity P38α MAP Kinase Inhibitors

Discovery of 2-Phenylamino-imidazo[4,5-h]isoquinolin-9-ones: A New Class of Inhibitors of Lck Kinase

Bioluminescent method for assaying multiple semicarbazide-sensitive amine oxidase (SSAO) family members in both 96- and 384-well formats

Optimization of 2-Phenylaminoimidazo[4,5-h]isoquinolin-9-ones: Orally Active Inhibitors of lck Kinase

IKKα, IKKβ, and NEMO/IKKγ Are Each Required for the NF-κB-mediated Inflammatory Response Program

The kinetics of binding to p38MAP kinase by analogues of BIRB 796

Novel NEMO/IκB Kinase and NF-κB Target Genes at the Pre-B to Immature B Cell Transition

IκB Kinases α and β Show a Random Sequential Kinetic Mechanism and Are Inhibited by Staurosporine and Quercetin

The kinetics of binding to p38 MAP kinase by analogues of BIRB 796

Non-Sialate Inhibitor of Influenza A/WSN/33 Neuraminidase

Recombinant IκB Kinases α and β Are Direct Kinases of IκBα

The discovery of thienopyridine analogues as potent I[kappa]B kinase beta inhibitors. Part II

IÎºB Kinases Î± and Î² Show a Random Sequential Kinetic Mechanism and Are Inhibited by Staurosporine and Quercetin

Catalysis and function of the p38 alpha.MK2a signaling complex

Thermal denaturation: a method to rank slow binding, high-affinity P38alpha MAP kinase inhibitors

Discovery and characterization of a substrate selective p38alpha inhibitor

IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program

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