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Hypoxia-Inducible Factor-1 Mediates Activation of Cultured Vascular Endothelial Cells by Inducing Multiple Angiogenic Factors

Circulation research, 2003-10, Vol.93 (7), p.664-673

2003

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Stabilization of Vascular Endothelial Growth Factor mRNA by Hypoxia-Inducible Factor 1

Biochemical and biophysical research communications, 2002-03, Vol.291 (4), p.908-914

2002

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Preclinical Evaluation of IMGC936, a Next Generation Maytansinoid-based Antibody-drug Conjugate Targeting ADAM9-expressing Tumors

Molecular cancer therapeutics, 2022-07, Vol.21 (7), p.1047-1059

2022

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Systemic Administration of AAV8-α-galactosidase A Induces Humoral Tolerance in Nonhuman Primates Despite Low Hepatic Expression

Molecular therapy, 2011-11, Vol.19 (11), p.1999-2011

2011

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Generation of cAMP-Activated Chloride Currents by Expression of CFTR

Science (American Association for the Advancement of Science), 1991-02, Vol.251 (4994), p.679-682

1991

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Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

Nature (London), 1990-09, Vol.347 (6291), p.358-363

1990

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Hypoxia-inducible factor 1 mediates hypoxia-induced cardiomyocyte lipid accumulation by reducing the DNA binding activity of peroxisome proliferator-activated receptor α/retinoid X receptor

Biochemical and biophysical research communications, 2007-12, Vol.364 (3), p.567-572

2007

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Expression and characterization of the cystic fibrosis transmembrane conductance regulator

Nature (London), 1990-09, Vol.347 (6291), p.382-386

1990

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Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1α/VP16 hybrid transcription factor

Circulation (New York, N.Y.), 2000-10, Vol.102 (18), p.2255-2261

2000

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Expression of constitutively stable hybrid hypoxia-inducible factor-1α protects cultured rat cardiomyocytes against simulated ischemia-reperfusion injury

American Journal of Physiology: Cell Physiology, 2005-02, Vol.288 (2), p.C314-C320

2005

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AAV2 Vector Harboring a Liver-Restricted Promoter Facilitates Sustained Expression of Therapeutic Levels of α-Galactosidase A and the Induction of Immune Tolerance in Fabry Mice

Molecular therapy, 2004-02, Vol.9 (2), p.231-240

2004

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A hypoxic inducible factor-1α hybrid enhances collateral development and reduces vascular leakage in diabetic rats

The journal of gene medicine, 2009-05, Vol.11 (5), p.390-400

2009

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A Constitutively Active Hypoxia-Inducible Factor-1α/VP16 Hybrid Factor Activates Expression of the Human B-Type Natriuretic Peptide Gene

Molecular pharmacology, 2006-06, Vol.69 (6), p.1953-1962

2006

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Myocardial expression of baculoviral p35 alleviates doxorubicin-induced cardiomyopathy in rats

Human gene therapy, 2003-07, Vol.14 (10), p.947-957

2003

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Demonstration that CFTR is a Chloride Channel by Alteration of its Anion Selectivity

Science (American Association for the Advancement of Science), 1991-07, Vol.253 (5016), p.202-205

1991

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Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

Cell, 1990-11, Vol.63 (4), p.827-834

1990

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Expression of angiopoietins in renal epithelial and clear cell carcinoma cells: regulation by hypoxia and participation in angiogenesis

American journal of physiology. Renal physiology, 2004-10, Vol.287 (4), p.F649-F657

2004

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Mutations in CFTR associated with mild-disease-form CI - channels with altered pore properties

Nature (London), 1993-03, Vol.362 (6416), p.160-164

1993

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Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

Cell, 1991-09, Vol.66 (5), p.1027-1036

1991

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Adenovirus-mediated expression of β-adrenergic receptor kinase C-terminus reduces intimal hyperplasia and luminal stenosis of arteriovenous polytetrafluoroethylene grafts in pigs

Circulation (New York, N.Y.), 2005-04, Vol.111 (13), p.1679-1684

2005

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Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats

Nature genetics, 1994-01, Vol.6 (1), p.75-83

1994

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Differential effects of membrane and soluble Fas ligand on cardiomyocytes: role in ischemia/reperfusion injury

Journal of molecular and cellular cardiology, 2003-07, Vol.35 (7), p.811-821

2003

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Gene expression profiles in human cardiac cells subjected to hypoxia or expressing a hybrid form of HIF-1 alpha

Physiological genomics, 2002-02, Vol.8 (1), p.23-32

2002

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Effect of Deleting the R Domain on CFTR-Generated Chloride Channels

Science (American Association for the Advancement of Science), 1991-07, Vol.253 (5016), p.205-207

1991

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Characterization of an adenovirus gene transfer vector containing an E4 deletion

Human gene therapy, 1995-10, Vol.6 (10), p.1343-1353

1995

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Hypoxia-Inducible Factor-1 Mediates Activation of Cultured Vascular Endothelial Cells by Inducing Multiple Angiogenic Factors

Stabilization of Vascular Endothelial Growth Factor mRNA by Hypoxia-Inducible Factor 1

Preclinical Evaluation of IMGC936, a Next Generation Maytansinoid-based Antibody-drug Conjugate Targeting ADAM9-expressing Tumors

Systemic Administration of AAV8-α-galactosidase A Induces Humoral Tolerance in Nonhuman Primates Despite Low Hepatic Expression

Generation of cAMP-Activated Chloride Currents by Expression of CFTR

Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

Hypoxia-inducible factor 1 mediates hypoxia-induced cardiomyocyte lipid accumulation by reducing the DNA binding activity of peroxisome proliferator-activated receptor α/retinoid X receptor

Expression and characterization of the cystic fibrosis transmembrane conductance regulator

Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1α/VP16 hybrid transcription factor

Expression of constitutively stable hybrid hypoxia-inducible factor-1α protects cultured rat cardiomyocytes against simulated ischemia-reperfusion injury

AAV2 Vector Harboring a Liver-Restricted Promoter Facilitates Sustained Expression of Therapeutic Levels of α-Galactosidase A and the Induction of Immune Tolerance in Fabry Mice

A hypoxic inducible factor-1α hybrid enhances collateral development and reduces vascular leakage in diabetic rats

A Constitutively Active Hypoxia-Inducible Factor-1α/VP16 Hybrid Factor Activates Expression of the Human B-Type Natriuretic Peptide Gene

Myocardial expression of baculoviral p35 alleviates doxorubicin-induced cardiomyopathy in rats

Demonstration that CFTR is a Chloride Channel by Alteration of its Anion Selectivity

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

Expression of angiopoietins in renal epithelial and clear cell carcinoma cells: regulation by hypoxia and participation in angiogenesis

Mutations in CFTR associated with mild-disease-form CI - channels with altered pore properties

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

Adenovirus-mediated expression of β-adrenergic receptor kinase C-terminus reduces intimal hyperplasia and luminal stenosis of arteriovenous polytetrafluoroethylene grafts in pigs

Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats

Differential effects of membrane and soluble Fas ligand on cardiomyocytes: role in ischemia/reperfusion injury

Gene expression profiles in human cardiac cells subjected to hypoxia or expressing a hybrid form of HIF-1 alpha

Effect of Deleting the R Domain on CFTR-Generated Chloride Channels

Characterization of an adenovirus gene transfer vector containing an E4 deletion

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