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Beta-Amyloid and Oxidative Stress Jointly Induce Neuronal Death, Amyloid Deposits, Gliosis, and Memory Impairment in the Rat Brain

Pharmacology, 2006-01, Vol.76 (1), p.19-33

2006

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Identification of a benzamide derivative that inhibits stress-induced adrenal corticosteroid synthesis

Molecules (Basel, Switzerland), 2009-09, Vol.14 (9), p.3392-3410

2009

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Dimethyl-carbamic acid 2,3-Bis-Dimethylcarbamoyloxy-6-(4-Ethyl-Piperazine-1-Carbonyl)-phenyl ester: a novel multi-target therapeutic approach to neuroprotection

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2010-05, Vol.6 (3), p.123-140

2010

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Inhibition of adrenal cortical steroid formation by procaine is mediated by reduction of the cAMP-induced 3-hydroxy-3-methylglutaryl-coenzyme A reductase messenger ribonucleic acid levels

The Journal of pharmacology and experimental therapeutics, 2003-12, Vol.307 (3), p.1148-1157

2003

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3D QSAR studies of AChE inhibitors based on molecular docking scores and CoMFA

Bioorganic & medicinal chemistry letters, 2006-12, Vol.16 (24), p.6277-6280

2006

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The spirostenol (22 R, 25 R)-20α-spirost-5-en-3β-yl hexanoate blocks mitochondrial uptake of Aβ in neuronal cells and prevents Aβ-induced impairment of mitochondrial function

Steroids, 2006-08, Vol.71 (8), p.725-735

2006

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Caprospinol: moving from a neuroactive steroid to a neurotropic drug

Expert opinion on investigational drugs, 2009-03, Vol.18 (3), p.265-276

2009

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Identification of naturally occurring spirostenols preventing β-amyloid-induced neurotoxicity

Steroids, 2004, Vol.69 (1), p.1-16

2004

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22R‐Hydroxycholesterol protects neuronal cells from β‐amyloid‐induced cytotoxicity by binding to β‐amyloid peptide

Journal of neurochemistry, 2002-12, Vol.83 (5), p.1110-1119

2002

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The spirostenol (22R, 25R)-20alpha-spirost-5-en-3beta-yl hexanoate blocks mitochondrial uptake of Abeta in neuronal cells and prevents Abeta-induced impairment of mitochondrial function

Steroids, 2006-08, Vol.71 (8), p.725

2006

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Methodology for Multi-Site Ligand-Protein Docking Identification Developed for the Optimization of Spirostenol Inhibition of [beta]-Amyloid-Induced Neurotoxicity

Chemistry & biodiversity, 2005-11, Vol.2 (11), p.1571-1579

2005

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Identification, design, synthesis, and pharmacological activity of (4-ethyl-piperazin-1-yl)-phenylmethanone derivatives with neuroprotective properties against β-amyloid-induced toxicity

Neuropharmacology, 2005-07, Vol.49 (1), p.86-96

2005

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Local Anesthetic Procaine Protects Rat Pheochromocytoma PC12 Cells against [beta]-Amyloid-Induced Neurotoxicity

Pharmacology, 2005-05, Vol.74 (2), p.65

2005

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Methodology for Multi-Site Ligand-Protein Docking Identification Developed for the Optimization of Spirostenol Inhibition of β-Amyloid-Induced Neurotoxicity

Chemistry & biodiversity, 2005-11, Vol.2 (11), p.1571-1579

2005

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Local Anesthetic Procaine Protects Rat Pheochromocytoma PC12 Cells against β-Amyloid-Induced Neurotoxicity

Pharmacology, 2005-05, Vol.74 (2), p.65-78

2005

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Amelioration of caspase 3,7 activity by SP01 in human primary neurons exposed to HIV

Neurobehavioral HIV medicine, 2010-07, Vol.2, p.33

Everall, Ian

2010

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22 R ‐Hydroxycholesterol protects neuronal cells from β‐amyloid‐induced cytotoxicity by binding to β‐amyloid peptide

Journal of neurochemistry, 2002-12, Vol.83 (5), p.1110-1119

2002

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The Benzamide Derivative N-[1-(7-tert-Butyl-1H-indol-3-ylmethyl)-2-(4-cyclopropanecarbonyl-3-methyl-piperazin-1-yl)-2-oxo-ethyl]-4-nitro-benzamide (SP-10) Reduces HIV-1 Infectivity in Vitro by Modifying Actin Dynamics

Antiviral chemistry & chemotherapy, 2006-12, Vol.17 (6), p.331-342

2006

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Cocaine Addiction

The Nursing clinics of North America, 1989-03, Vol.24 (1), p.33-43

1989

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Beta-Amyloid and Oxidative Stress Jointly Induce Neuronal Death, Amyloid Deposits, Gliosis, and Memory Impairment in the Rat Brain

Identification of a benzamide derivative that inhibits stress-induced adrenal corticosteroid synthesis

Dimethyl-carbamic acid 2,3-Bis-Dimethylcarbamoyloxy-6-(4-Ethyl-Piperazine-1-Carbonyl)-phenyl ester: a novel multi-target therapeutic approach to neuroprotection

Inhibition of adrenal cortical steroid formation by procaine is mediated by reduction of the cAMP-induced 3-hydroxy-3-methylglutaryl-coenzyme A reductase messenger ribonucleic acid levels

3D QSAR studies of AChE inhibitors based on molecular docking scores and CoMFA

The spirostenol (22 R, 25 R)-20α-spirost-5-en-3β-yl hexanoate blocks mitochondrial uptake of Aβ in neuronal cells and prevents Aβ-induced impairment of mitochondrial function

Caprospinol: moving from a neuroactive steroid to a neurotropic drug

Identification of naturally occurring spirostenols preventing β-amyloid-induced neurotoxicity

22R‐Hydroxycholesterol protects neuronal cells from β‐amyloid‐induced cytotoxicity by binding to β‐amyloid peptide

The spirostenol (22R, 25R)-20alpha-spirost-5-en-3beta-yl hexanoate blocks mitochondrial uptake of Abeta in neuronal cells and prevents Abeta-induced impairment of mitochondrial function

Methodology for Multi-Site Ligand-Protein Docking Identification Developed for the Optimization of Spirostenol Inhibition of [beta]-Amyloid-Induced Neurotoxicity

Identification, design, synthesis, and pharmacological activity of (4-ethyl-piperazin-1-yl)-phenylmethanone derivatives with neuroprotective properties against β-amyloid-induced toxicity

Local Anesthetic Procaine Protects Rat Pheochromocytoma PC12 Cells against [beta]-Amyloid-Induced Neurotoxicity

Methodology for Multi-Site Ligand-Protein Docking Identification Developed for the Optimization of Spirostenol Inhibition of β-Amyloid-Induced Neurotoxicity

Local Anesthetic Procaine Protects Rat Pheochromocytoma PC12 Cells against β-Amyloid-Induced Neurotoxicity

Amelioration of caspase 3,7 activity by SP01 in human primary neurons exposed to HIV

22 R ‐Hydroxycholesterol protects neuronal cells from β‐amyloid‐induced cytotoxicity by binding to β‐amyloid peptide

The Benzamide Derivative N-[1-(7-tert-Butyl-1H-indol-3-ylmethyl)-2-(4-cyclopropanecarbonyl-3-methyl-piperazin-1-yl)-2-oxo-ethyl]-4-nitro-benzamide (SP-10) Reduces HIV-1 Infectivity in Vitro by Modifying Actin Dynamics

Cocaine Addiction

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