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Rspo2/Int7 regulates invasiveness and tumorigenic properties of mammary epithelial cells

Journal of cellular physiology, 2012-05, Vol.227 (5), p.1960-1971

2012

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ONC201: Stressing tumors to death

Science signaling, 2016-02, Vol.9 (415), p.fs1

2016

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MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer

Breast cancer research : BCR, 2019-02, Vol.21 (1), p.27-17, Article 27

2019

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Targeting Mitochondria with ClpP Agonists as a Novel Therapeutic Opportunity in Breast Cancer

Cancers, 2023-03, Vol.15 (7), p.1936

2023

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Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth

The Journal of cell biology, 2011-03, Vol.192 (6), p.993-1004

2011

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Targeting TRAIL Death Receptors in Triple-Negative Breast Cancers: Challenges and Strategies for Cancer Therapy

Cells (Basel, Switzerland), 2022-11, Vol.11 (23), p.3717

2022

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Lack of Casein Kinase 1 Delta Promotes Genomic Instability - The Accumulation of DNA Damage and Down-Regulation of Checkpoint Kinase 1

PloS one, 2017-01, Vol.12 (1), p.e0170903-e0170903

2017

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Mitochondrial Matrix Protease ClpP Agonists Inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis

Cancer research communications, 2022-10, Vol.2 (10), p.1144-1161

2022

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Characterization of TR‐107, a novel chemical activator of the human mitochondrial protease ClpP

Pharmacology research & perspectives, 2022-08, Vol.10 (4), p.e00993-n/a

2022

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The role of centrosomal casein kinase 1 delta in neurite outgrowth and beyond

Cell cycle (Georgetown, Tex.), 2011-08, Vol.10 (16), p.2605-2606

2011

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Dual-inhibition of NAMPT and PAK4 induces anti-tumor effects in 3D-spheroids model of platinum-resistant ovarian cancer

Cancer gene therapy, 2024-05, Vol.31 (5), p.721-735

2024

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TIC10/ONC201: a bend in the road to clinical development

Oncoscience, 2015, Vol.2 (2), p.75-76

2015

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ONC201 kills breast cancer cells in vitro by targeting mitochondria

Oncotarget, 2018-04, Vol.9 (26), p.18454-18479

2018

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A Single-Arm, Open-Label Phase II Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma

The oncologist (Dayton, Ohio), 2023-10, Vol.28 (10), p.919-e972

2023

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Abstract 2539: Tumor necrosis factor related apoptosis inducing ligand (TRAIL) induces cytokine release via the alternative NFKB2 pathway in triple negative breast cancer cells (TNBC) and modulates neutrophil chemotaxis

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2539-2539

2023

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Abstract 347: Tumor necrosis factor related apoptosis inducing ligand (TRAIL)-induced cytokine production in TNBC promotes neutrophil chemotaxis and immune suppression

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.347-347

2024

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Abstract 1335: Lack of casein kinase 1 delta induces DNA damage, inhibition of mTORC1 signaling and nucleophagy

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.1335-1335

2014

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Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis

Molecular biology of the cell, 2014-05, Vol.25 (10), p.1629-1640

2014

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MEDI3039, a novel highly potent tumor necrosis factor receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer

Breast cancer research : BCR, 2019-02, Vol.21 (1)

2019

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Functional Consequences of Wnt-induced Dishevelled 2 Phosphorylation in Canonical and Noncanonical Wnt Signaling

The Journal of biological chemistry, 2013-03, Vol.288 (13), p.9428-9437

2013

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Atypical Protein Kinase Cι Is Required for Wnt3a-dependent Neurite Outgrowth and Binds to Phosphorylated Dishevelled 2

The Journal of biological chemistry, 2013-03, Vol.288 (13), p.9438-9446

2013

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Abstract B023: ONC201 kills breast cancer cells by targeting mitochondria

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.B023-B023

2018

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Rspo2/Int7 regulates invasiveness and tumorigenic properties of mammary epithelial cells

ONC201: Stressing tumors to death

MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer

Targeting Mitochondria with ClpP Agonists as a Novel Therapeutic Opportunity in Breast Cancer

Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth

Targeting TRAIL Death Receptors in Triple-Negative Breast Cancers: Challenges and Strategies for Cancer Therapy

Lack of Casein Kinase 1 Delta Promotes Genomic Instability - The Accumulation of DNA Damage and Down-Regulation of Checkpoint Kinase 1

Mitochondrial Matrix Protease ClpP Agonists Inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis

Characterization of TR‐107, a novel chemical activator of the human mitochondrial protease ClpP

The role of centrosomal casein kinase 1 delta in neurite outgrowth and beyond

Dual-inhibition of NAMPT and PAK4 induces anti-tumor effects in 3D-spheroids model of platinum-resistant ovarian cancer

TIC10/ONC201: a bend in the road to clinical development

ONC201 kills breast cancer cells in vitro by targeting mitochondria

A Single-Arm, Open-Label Phase II Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma

Abstract 2539: Tumor necrosis factor related apoptosis inducing ligand (TRAIL) induces cytokine release via the alternative NFKB2 pathway in triple negative breast cancer cells (TNBC) and modulates neutrophil chemotaxis

Abstract 347: Tumor necrosis factor related apoptosis inducing ligand (TRAIL)-induced cytokine production in TNBC promotes neutrophil chemotaxis and immune suppression

Abstract 1335: Lack of casein kinase 1 delta induces DNA damage, inhibition of mTORC1 signaling and nucleophagy

Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis

MEDI3039, a novel highly potent tumor necrosis factor receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer

Functional Consequences of Wnt-induced Dishevelled 2 Phosphorylation in Canonical and Noncanonical Wnt Signaling

Atypical Protein Kinase Cι Is Required for Wnt3a-dependent Neurite Outgrowth and Binds to Phosphorylated Dishevelled 2

Abstract B023: ONC201 kills breast cancer cells by targeting mitochondria

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