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Pathological Axonal Death through a MAPK Cascade that Triggers a Local Energy Deficit

Cell, 2015-01, Vol.160 (1-2), p.161-176

2015

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Neuropilin-1 Knockout and Rescue Confirms Its Role to Promote Metastasis in MDA-MB-231 Breast Cancer Cells

International journal of molecular sciences, 2023-04, Vol.24 (9), p.7792

2023

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Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy

Diabetes (New York, N.Y.), 2016-01, Vol.65 (1), p.255-268

2016

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Myeloid cell-specific deletion of Capns1 prevents macrophage polarization toward the M1 phenotype and reduces interstitial lung disease in the bleomycin model of systemic sclerosis

Arthritis research & therapy, 2022-06, Vol.24 (1), p.1-148, Article 148

2022

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A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (49), p.17355-17355

2014

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HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer

Genes & development, 2016-07, Vol.30 (13), p.1542-1557

2016

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Ezrin regulates focal adhesion and invadopodia dynamics by altering calpain activity to promote breast cancer cell invasion

Molecular biology of the cell, 2015-10, Vol.26 (19), p.3464-3479

2015

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Intravital imaging reveals systemic ezrin inhibition impedes cancer cell migration and lymph node metastasis in breast cancer

Breast cancer research : BCR, 2019-01, Vol.21 (1), p.12-12, Article 12

2019

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IL-27 Improves Prophylactic Protection Provided by a Dead Tumor Cell Vaccine in a Mouse Melanoma Model

Frontiers in immunology, 2022-04, Vol.13, p.884827-884827

2022

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Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis

Molecular and cellular biology, 2016-08, Vol.36 (15), p.2078-2088

2016

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Sequential Activation of Poly(ADP-Ribose) Polymerase 1, Calpains, and Bax Is Essential in Apoptosis-Inducing Factor-Mediated Programmed Necrosis

Molecular and Cellular Biology, 2007-07, Vol.27 (13), p.4844-4862

2007

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Targeted inhibition of calpain reduces myocardial hypertrophy and fibrosis in mouse models of type 1 diabetes

Diabetes (New York, N.Y.), 2011-11, Vol.60 (11), p.2985-2994

2011

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Citrullination Licenses Calpain to Decondense Nuclei in Neutrophil Extracellular Trap Formation

Frontiers in immunology, 2019-10, Vol.10, p.2481-2481

2019

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Ubiquitous Calpains Promote Caspase-12 and JNK Activation during Endoplasmic Reticulum Stress-induced Apoptosis

The Journal of biological chemistry, 2006-06, Vol.281 (23), p.16016-16024

2006

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Promotion of a synthetic degradation of activated STAT6 by PARP-1 inhibition: roles of poly(ADP-ribosyl)ation, calpains and autophagy

Journal of translational medicine, 2022-11, Vol.20 (1), p.521-521, Article 521

2022

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Recurrent copy number alterations in prostate cancer: an in silico meta-analysis of publicly available genomic data

Cancer genetics, 2014-10, Vol.207 (10), p.474-488

2014

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Establishing the role of the FES tyrosine kinase in the pathogenesis, pathophysiology, and severity of sepsis and its outcomes

Frontiers in immunology, 2023-04, Vol.14, p.1145826-1145826

2023

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Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury

The Journal of neuroscience, 2013-03, Vol.33 (13), p.5773-5784

2013

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Crosstalk between calpain activation and TGF-β1 augments collagen-I synthesis in pulmonary fibrosis

Biochimica et biophysica acta. Molecular basis of disease, 2015-09, Vol.1852 (9), p.1796-1804

2015

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Ubiquitous Calpains Promote Both Apoptosis and Survival Signals in Response to Different Cell Death Stimuli

The Journal of biological chemistry, 2006-06, Vol.281 (26), p.17689-17698

2006

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An easy-to-use FRET protein substrate to detect calpain cleavage in vitro and in vivo

Biochimica et biophysica acta. Molecular cell research, 2018-02, Vol.1865 (2), p.221-230

2018

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Calpain 2 Activation of P-TEFb Drives Megakaryocyte Morphogenesis and Is Disrupted by Leukemogenic GATA1 Mutation

Developmental cell, 2013-12, Vol.27 (6), p.607-620

2013

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Calpain as a therapeutic target in cancer

Expert opinion on therapeutic targets, 2022-03, Vol.26 (3), p.217-231

2022

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Calpains promote neutrophil recruitment and bacterial clearance in an acute bacterial peritonitis model

European journal of immunology, 2014-03, Vol.44 (3), p.831-841

2014

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Fer-Mediated Cortactin Phosphorylation Is Associated with Efficient Fibroblast Migration and Is Dependent on Reactive Oxygen Species Generation during Integrin-Mediated Cell Adhesion

Molecular and Cellular Biology, 2007-09, Vol.27 (17), p.6140-6152

2007

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Pathological Axonal Death through a MAPK Cascade that Triggers a Local Energy Deficit

Neuropilin-1 Knockout and Rescue Confirms Its Role to Promote Metastasis in MDA-MB-231 Breast Cancer Cells

Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy

Myeloid cell-specific deletion of Capns1 prevents macrophage polarization toward the M1 phenotype and reduces interstitial lung disease in the bleomycin model of systemic sclerosis

A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome

HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer

Ezrin regulates focal adhesion and invadopodia dynamics by altering calpain activity to promote breast cancer cell invasion

Intravital imaging reveals systemic ezrin inhibition impedes cancer cell migration and lymph node metastasis in breast cancer

IL-27 Improves Prophylactic Protection Provided by a Dead Tumor Cell Vaccine in a Mouse Melanoma Model

Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis

Sequential Activation of Poly(ADP-Ribose) Polymerase 1, Calpains, and Bax Is Essential in Apoptosis-Inducing Factor-Mediated Programmed Necrosis

Targeted inhibition of calpain reduces myocardial hypertrophy and fibrosis in mouse models of type 1 diabetes

Citrullination Licenses Calpain to Decondense Nuclei in Neutrophil Extracellular Trap Formation

Ubiquitous Calpains Promote Caspase-12 and JNK Activation during Endoplasmic Reticulum Stress-induced Apoptosis

Promotion of a synthetic degradation of activated STAT6 by PARP-1 inhibition: roles of poly(ADP-ribosyl)ation, calpains and autophagy

Recurrent copy number alterations in prostate cancer: an in silico meta-analysis of publicly available genomic data

Establishing the role of the FES tyrosine kinase in the pathogenesis, pathophysiology, and severity of sepsis and its outcomes

Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury

Crosstalk between calpain activation and TGF-β1 augments collagen-I synthesis in pulmonary fibrosis

Ubiquitous Calpains Promote Both Apoptosis and Survival Signals in Response to Different Cell Death Stimuli

An easy-to-use FRET protein substrate to detect calpain cleavage in vitro and in vivo

Calpain 2 Activation of P-TEFb Drives Megakaryocyte Morphogenesis and Is Disrupted by Leukemogenic GATA1 Mutation

Calpain as a therapeutic target in cancer

Calpains promote neutrophil recruitment and bacterial clearance in an acute bacterial peritonitis model

Fer-Mediated Cortactin Phosphorylation Is Associated with Efficient Fibroblast Migration and Is Dependent on Reactive Oxygen Species Generation during Integrin-Mediated Cell Adhesion

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