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Regulatory T Cells: Regulation of Identity and Function

Frontiers in immunology, 2021-10, Vol.12, p.750542-750542

2021

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Foxp3 Post-translational Modifications and Treg Suppressive Activity

Frontiers in immunology, 2019-10, Vol.10, p.2486-2486

2019

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The Ubiquitin Ligase Stub1 Negatively Modulates Regulatory T Cell Suppressive Activity by Promoting Degradation of the Transcription Factor Foxp3

Immunity (Cambridge, Mass.), 2013-08, Vol.39 (2), p.272-285

2013

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Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

Nature immunology, 2008-02, Vol.9 (2), p.194-202

2008

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Survivin as a Therapeutic Target for the Treatment of Human Cancer

Cancers, 2024-05, Vol.16 (9), p.1705

2024

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PRMT5 Is Required for T Cell Survival and Proliferation by Maintaining Cytokine Signaling

Frontiers in immunology, 2020-04, Vol.11, p.621-621

2020

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Atomic description of the immune complex involved in heparin-induced thrombocytopenia

Nature communications, 2015-09, Vol.6 (1), p.8277-8277, Article 8277

2015

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ErbB receptors: from oncogenes to targeted cancer therapies

The Journal of clinical investigation, 2007-08, Vol.117 (8), p.2051-2058

2007

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Dynamic Interactions between TIP60 and p300 Regulate FOXP3 Function through a Structural Switch Defined by a Single Lysine on TIP60

Cell reports (Cambridge), 2014-06, Vol.7 (5), p.1471-1480

2014

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FOXP3 Interactions with Histone Acetyltransferase and Class II Histone Deacetylases Are Required for Repression

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (11), p.4571-4576

2007

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HED, a Human-Engineered Domain, Confers a Unique Fc-Binding Activity to Produce a New Class of Humanized Antibody-like Molecules

International journal of molecular sciences, 2023-03, Vol.24 (7), p.6477

2023

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Sequential Anti-PD1 Therapy Following Dendritic Cell Vaccination Improves Survival in a HER2 Mammary Carcinoma Model and Identifies a Critical Role for CD4 T Cells in Mediating the Response

Frontiers in immunology, 2019-08, Vol.10, p.1939-1939

2019

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Structural insights into SUN-KASH complexes across the nuclear envelope

Cell research, 2012-10, Vol.22 (10), p.1440-1452

2012

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Expression and function of ErbB receptors and ligands in the pituitary

Endocrine-related cancer, 2011-12, Vol.18 (6), p.R197-R211

2011

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Structural Features and PF4 Functions that Occur in Heparin-Induced Thrombocytopenia (HIT) Complicated by COVID-19

Antibodies (Basel), 2020-10, Vol.9 (4), p.52

2020

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Structure of Sad1-UNC84 Homology (SUN) Domain Defines Features of Molecular Bridge in Nuclear Envelope

The Journal of biological chemistry, 2012-02, Vol.287 (8), p.5317-5326

2012

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Novel TNF receptor-1 inhibitors identified as potential therapeutic candidates for traumatic brain injury

Journal of neuroinflammation, 2018-05, Vol.15 (1), p.154-154, Article 154

2018

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TGF-β and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (37), p.14023-14027

2008

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Carbohydrate Sequence of the Prostate Cancer-associated Antigen F77 Assigned by a Mucin O-Glycome Designer Array

The Journal of biological chemistry, 2014-06, Vol.289 (23), p.16462-16477

2014

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Determination of Carbohydrate Structure Recognized by Prostate-specific F77 Monoclonal Antibody through Expression Analysis of Glycosyltransferase Genes

The Journal of biological chemistry, 2014-06, Vol.289 (23), p.16478-16486

2014

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Disabling of the erbB Pathway Followed by IFN-γ Modifies Phenotype and Enhances Genotoxic Eradication of Breast Tumors

Cell reports (Cambridge), 2015-09, Vol.12 (12), p.2049-2059

2015

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Immune regulation by histone deacetylases: a focus on the alteration of FOXP3 activity

Immunology and cell biology, 2012-01, Vol.90 (1), p.95-100

2012

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Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function

Cell reports (Cambridge), 2012-06, Vol.1 (6), p.665-675

2012

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The role of HER2 in early breast cancer metastasis and the origins of resistance to HER2-targeted therapies

Experimental and molecular pathology, 2009-08, Vol.87 (1), p.1-11

2009

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A targeted immunotherapy approach for HER2/neu transformed tumors by coupling an engineered effector domain with interferon-γ

Oncoimmunology, 2018-04, Vol.7 (4), p.e1300739-e1300739

2018

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Regulatory T Cells: Regulation of Identity and Function

Foxp3 Post-translational Modifications and Treg Suppressive Activity

The Ubiquitin Ligase Stub1 Negatively Modulates Regulatory T Cell Suppressive Activity by Promoting Degradation of the Transcription Factor Foxp3

Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

Survivin as a Therapeutic Target for the Treatment of Human Cancer

PRMT5 Is Required for T Cell Survival and Proliferation by Maintaining Cytokine Signaling

Atomic description of the immune complex involved in heparin-induced thrombocytopenia

ErbB receptors: from oncogenes to targeted cancer therapies

Dynamic Interactions between TIP60 and p300 Regulate FOXP3 Function through a Structural Switch Defined by a Single Lysine on TIP60

FOXP3 Interactions with Histone Acetyltransferase and Class II Histone Deacetylases Are Required for Repression

HED, a Human-Engineered Domain, Confers a Unique Fc-Binding Activity to Produce a New Class of Humanized Antibody-like Molecules

Sequential Anti-PD1 Therapy Following Dendritic Cell Vaccination Improves Survival in a HER2 Mammary Carcinoma Model and Identifies a Critical Role for CD4 T Cells in Mediating the Response

Structural insights into SUN-KASH complexes across the nuclear envelope

Expression and function of ErbB receptors and ligands in the pituitary

Structural Features and PF4 Functions that Occur in Heparin-Induced Thrombocytopenia (HIT) Complicated by COVID-19

Structure of Sad1-UNC84 Homology (SUN) Domain Defines Features of Molecular Bridge in Nuclear Envelope

Novel TNF receptor-1 inhibitors identified as potential therapeutic candidates for traumatic brain injury

TGF-β and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3

Carbohydrate Sequence of the Prostate Cancer-associated Antigen F77 Assigned by a Mucin O-Glycome Designer Array

Determination of Carbohydrate Structure Recognized by Prostate-specific F77 Monoclonal Antibody through Expression Analysis of Glycosyltransferase Genes

Disabling of the erbB Pathway Followed by IFN-γ Modifies Phenotype and Enhances Genotoxic Eradication of Breast Tumors

Immune regulation by histone deacetylases: a focus on the alteration of FOXP3 activity

Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function

The role of HER2 in early breast cancer metastasis and the origins of resistance to HER2-targeted therapies

A targeted immunotherapy approach for HER2/neu transformed tumors by coupling an engineered effector domain with interferon-γ

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