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Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding

Cell, 2020-09, Vol.182 (5), p.1295-1310.e20

2020

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Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016

Cell reports. Medicine, 2021-04, Vol.2 (4), p.100255-100255, Article 100255

2021

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Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection

Science translational medicine, 2021-06, Vol.13 (600)

2021

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Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

PLoS pathogens, 2022-11, Vol.18 (11), p.e1010951-e1010951

2022

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Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies

Cell host & microbe, 2021-03, Vol.29 (3), p.463-476.e6

2021

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Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies

Nature communications, 2021-07, Vol.12 (1), p.4196-4196, Article 4196

2021

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Prospective mapping of viral mutations that escape antibodies used to treat COVID-19

Science (American Association for the Advancement of Science), 2021-02, Vol.371 (6531), p.850-854

2021

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ACE2 binding is an ancestral and evolvable trait of sarbecoviruses

Nature (London), 2022-03, Vol.603 (7903), p.913-918

2022

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Molecular fate-mapping of serum antibody responses to repeat immunization

Nature (London), 2023-03, Vol.615 (7952), p.482-489

2023

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Sulforaphane inhibits multiple inflammasomes through an Nrf2‐independent mechanism

Journal of leukocyte biology, 2016-01, Vol.99 (1), p.189-199

2016

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Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1

Nature communications, 2022-11, Vol.13 (1), p.7011-11, Article 7011

2022

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Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition

Cell host & microbe, 2021-01, Vol.29 (1), p.44-57.e9

2021

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The History of Engineered Tracheal Replacements: Interpreting the Past and Guiding the Future

Tissue engineering. Part B, Reviews, 2021-08, Vol.27 (4), p.341-352

2021

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Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution

Science (American Association for the Advancement of Science), 2022-07, Vol.377 (6604), p.420-424

2022

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Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids

Nature communications, 2022-01, Vol.13 (1), p.430-15, Article 430

2022

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The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes

PLoS pathogens, 2022-06, Vol.18 (6), p.e1010592-e1010592

2022

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Bacterial Exotoxins and the Inflammasome

Frontiers in immunology, 2015-11, Vol.6, p.570-570

2015

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Attenuated Influenza Virions Expressing the SARS-CoV-2 Receptor-Binding Domain Induce Neutralizing Antibodies in Mice

Viruses, 2020-09, Vol.12 (9), p.987

2020

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An antibody-escape estimator for mutations to the SARS-CoV-2 receptor-binding domain

Virus evolution, 2022, Vol.8 (1), p.veac021-veac021

2022

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Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models

Science (American Association for the Advancement of Science), 2022-08, Vol.377 (6606), p.eabq0839

2022

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Computation and visualization of cell-cell signaling topologies in single-cell systems data using Connectome

Scientific reports, 2022-03, Vol.12 (1), p.4187-4187, Article 4187

2022

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Geochemistry of molybdenum in the continental crust

Geochimica et cosmochimica acta, 2018-10, Vol.238, p.36-54

2018

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The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution

eLife, 2023-02, Vol.12

2023

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The Rosetteless gene controls development in the choanoflagellate S. rosetta

eLife, 2014-10, Vol.3

2014

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Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding

Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016

Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection

Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies

Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies

Prospective mapping of viral mutations that escape antibodies used to treat COVID-19

ACE2 binding is an ancestral and evolvable trait of sarbecoviruses

Molecular fate-mapping of serum antibody responses to repeat immunization

Sulforaphane inhibits multiple inflammasomes through an Nrf2‐independent mechanism

Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1

Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition

The History of Engineered Tracheal Replacements: Interpreting the Past and Guiding the Future

Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution

Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids

Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes

The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes

Bacterial Exotoxins and the Inflammasome

Attenuated Influenza Virions Expressing the SARS-CoV-2 Receptor-Binding Domain Induce Neutralizing Antibodies in Mice

An antibody-escape estimator for mutations to the SARS-CoV-2 receptor-binding domain

Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models

Computation and visualization of cell-cell signaling topologies in single-cell systems data using Connectome

Geochemistry of molybdenum in the continental crust

The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution

The Rosetteless gene controls development in the choanoflagellate S. rosetta

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