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Amifostine reduces lung vascular permeability via suppression of inflammatory signalling

The European respiratory journal, 2009-03, Vol.33 (3), p.612-624

2009

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CyclinB1/Cdk1 phosphorylates mitochondrial antioxidant MnSOD in cell adaptive response to radiation stress

Journal of molecular cell biology, 2013-06, Vol.5 (3), p.166-175

2013

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SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine

Free radical biology & medicine, 2011-11, Vol.51 (10), p.1918-1925

2011

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Oxymetry Deep in Tissues With Low-Frequency Electron Paramagnetic Resonance

Proceedings of the National Academy of Sciences - PNAS, 1994-12, Vol.91 (26), p.13047-13051

1994

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Diminished aqueous microviscosity of tumors in murine models measured with in vivo radiofrequency electron paramagnetic resonance

Cancer research (Chicago, Ill.), 1999-11, Vol.59 (22), p.5836-5841

1999

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Method of RNA Purification from Endothelial Cells for DNA Array Experiments

BioTechniques, 2002-02, Vol.32 (2), p.316-320

2002

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Further evidence that the radioprotective aminothiol, WR-1065, catalytically inactivates mammalian topoisomerase II

Cancer research (Chicago, Ill.), 2000-03, Vol.60 (5), p.1186-1188

2000

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Cytoprotection by WR-1065, the active form of amifostine, is independent of p53 status in human malignant glioma cell lines

International journal of radiation biology, 2000, Vol.76 (5), p.633-639

Kataoka, J. S. Murley, R. Patel, D. J. Grdina, Y.

2000

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Antimutagenic effects of amifostine : Clinical implications

Seminars in oncology, 1996-08, Vol.23 (4), p.53-57

1996

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Activation of NFκB and MnSOD gene expression by free radical scavengers in human microvascular endothelial cells

Free radical biology & medicine, 2001-06, Vol.30 (12), p.1426-1439

2001

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Radiosensitivity of Mammalian Cell Lines Engineered to Overexpress Cytosolic Glutathione Peroxidase

Radiation research, 2001-04, Vol.155 (4), p.536-542

2001

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Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine

Carcinogenesis (New York), 1997-12, Vol.18 (12), p.2457-2459

1997

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Protection against radiation-induced mutagenesis at the hprt locus by spermine and N, N″-(dithiodi-2, 1-ethanediyl)bis-1,3-propanediamine (WR-33278)

Mutagenesis, 1994-07, Vol.9 (4), p.355-360

1994

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Inhibition of topoisomerase II alpha activity in CHO K1 cells by 2-[(aminopropyl)amino]ethanethiol (WR-1065)

Radiation research, 1994-04, Vol.138 (1), p.44

1994

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The radioprotector WR-2721 reduces neutron-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in mouse splenocytes when administered prior to or following irradiation

Carcinogenesis (New York), 1992-05, Vol.13 (5), p.811-814

1992

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Chemopreventive doses of amifostine confer no cytoprotection to tumor nodules growing in the lungs of mice treated with cyclophosphamide

Seminars in oncology, 1999-04, Vol.26 (2 Suppl 7), p.22

1999

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Expression of thymidine kinase messenger RNA and a related transcript is modulated by radioprotector WR1065

Cancer research (Chicago, Ill.), 1995-11, Vol.55 (21), p.4788-4792

1995

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Protection against AZT-induced mutagenesis at the HGPRT locus in a human cell line by WR-151326

International Journal of Radiation Oncology, Biology, & Physics. 1992, 1992, Vol.22 (4), p.813-815

1992

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WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase IIα leading to changes in enzyme activity and cell cycle progression in CHO AA8 cells

Cell proliferation, 1997-06, Vol.30 (6-7), p.283-294

1997

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Radioprotectors: current status and new directions

Radiation research, 2005-06, Vol.163 (6), p.704

2005

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The effects of cycloheximide and WR-1065 on radiation-induced repair processes: a mechanism for chemoprevention

Carcinogenesis (New York), 1995-11, Vol.16 (11), p.2699-2705

1995

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The effect of 2-[(aminopropyl)amino] ethanethiol (WR1065) on radiation-induced DNA damage and repair and cell progression in V79 cells

British journal of cancer, 1986-12, Vol.54 (6), p.933-941

1986

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Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anti-cytotoxic and anti-mutagenic mechanisms of action

Carcinogenesis (New York), 1995-04, Vol.16 (4), p.767-774

1995

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Effects of thiols on topoisomerase-IIα activity and cell cycle progression

Cell proliferation, 1998-10, Vol.31 (5-6), p.217-229

1998

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Radiation-induced DNA Double-strand Break Frequencies in Human Squamous Cell Carcinoma Cell Lines of Different Radiation Sensitivities

International journal of radiation biology, 1991, Vol.59 (6), p.1341-1352

1991

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Amifostine reduces lung vascular permeability via suppression of inflammatory signalling

CyclinB1/Cdk1 phosphorylates mitochondrial antioxidant MnSOD in cell adaptive response to radiation stress

SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine

Oxymetry Deep in Tissues With Low-Frequency Electron Paramagnetic Resonance

Diminished aqueous microviscosity of tumors in murine models measured with in vivo radiofrequency electron paramagnetic resonance

Method of RNA Purification from Endothelial Cells for DNA Array Experiments

Further evidence that the radioprotective aminothiol, WR-1065, catalytically inactivates mammalian topoisomerase II

Cytoprotection by WR-1065, the active form of amifostine, is independent of p53 status in human malignant glioma cell lines

Antimutagenic effects of amifostine : Clinical implications

Activation of NFκB and MnSOD gene expression by free radical scavengers in human microvascular endothelial cells

Radiosensitivity of Mammalian Cell Lines Engineered to Overexpress Cytosolic Glutathione Peroxidase

Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine

Protection against radiation-induced mutagenesis at the hprt locus by spermine and N, N″-(dithiodi-2, 1-ethanediyl)bis-1,3-propanediamine (WR-33278)

Inhibition of topoisomerase II alpha activity in CHO K1 cells by 2-[(aminopropyl)amino]ethanethiol (WR-1065)

The radioprotector WR-2721 reduces neutron-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in mouse splenocytes when administered prior to or following irradiation

Chemopreventive doses of amifostine confer no cytoprotection to tumor nodules growing in the lungs of mice treated with cyclophosphamide

Expression of thymidine kinase messenger RNA and a related transcript is modulated by radioprotector WR1065

Protection against AZT-induced mutagenesis at the HGPRT locus in a human cell line by WR-151326

WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase IIα leading to changes in enzyme activity and cell cycle progression in CHO AA8 cells

Radioprotectors: current status and new directions

The effects of cycloheximide and WR-1065 on radiation-induced repair processes: a mechanism for chemoprevention

The effect of 2-[(aminopropyl)amino] ethanethiol (WR1065) on radiation-induced DNA damage and repair and cell progression in V79 cells

Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anti-cytotoxic and anti-mutagenic mechanisms of action

Effects of thiols on topoisomerase-IIα activity and cell cycle progression

Radiation-induced DNA Double-strand Break Frequencies in Human Squamous Cell Carcinoma Cell Lines of Different Radiation Sensitivities

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