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Platelets Are Critical Key Players in Sepsis

International journal of molecular sciences, 2019-07, Vol.20 (14), p.3494

2019

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PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity

EMBO reports, 2021-06, Vol.22 (6), p.e51299-n/a

2021

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The lipid products of phosphoinositide 3-kinase isoforms in cancer and thrombosis

Cancer and metastasis reviews, 2018-09, Vol.37 (2-3), p.477-489

2018

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Role of oculocerebrorenal syndrome of Lowe (OCRL) protein in megakaryocyte maturation, platelet production and functions: a study in patients with Lowe syndrome

British journal of haematology, 2021-03, Vol.192 (5), p.909-921

2021

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Platelet activation and prothrombotic properties in a mouse model of peritoneal sepsis

Scientific reports, 2018-09, Vol.8 (1), p.13536-12, Article 13536

2018

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SHIP1 Controls Internal Platelet Contraction and αIIbβ3 Integrin Dynamics in Early Platelet Activation

International journal of molecular sciences, 2023-01, Vol.24 (2), p.958

2023

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Kinetics of mean platelet volume predicts mortality in patients with septic shock

PloS one, 2019-10, Vol.14 (10), p.e0223553-e0223553

2019

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Phosphoinositides take a central stage in regulating blood platelet production and function

Advances in biological regulation, 2024-01, Vol.91, p.100992, Article 100992

2024

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Platelet P2Y1 receptor exhibits constitutive G protein signaling and β-arrestin 2 recruitment

BMC biology, 2023-02, Vol.21 (1), p.1-14, Article 14

2023

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Targeting Kinases in Cancer Therapies: Adverse Effects on Blood Platelets

Current pharmaceutical design, 2016-01, Vol.22 (16), p.2315-2322

2016

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Evolution of platelet activation parameters during septic shock in intensive care unit

Platelets (Edinburgh), 2022-08, Vol.33 (6), p.918-925

2022

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The new tyrosine-kinase inhibitor and anticancer drug dasatinib reversibly affects platelet activation in vitro and in vivo

Blood, 2009-08, Vol.114 (9), p.1884-1892

2009

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Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion

Blood, 2007-11, Vol.110 (9), p.3183-3191

2007

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Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolism

JHEP reports, 2024-01, Vol.6 (1), p.100930-100930, Article 100930

2024

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Exploring the Role of PI3P in Platelets: Insights from a Novel External PI3P Pool

Biomolecules (Basel, Switzerland), 2023-03, Vol.13 (4), p.583

2023

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Platelet Versus Megakaryocyte: Who Is the Real Bandleader of Thromboinflammation in Sepsis?

Cells (Basel, Switzerland), 2022-04, Vol.11 (9), p.1507

2022

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G13 is an essential mediator of platelet activation in hemostasis and thrombosis

Nature medicine, 2003-11, Vol.9 (11), p.1418-1422

2003

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A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples

Biochemical journal, 2012-10, Vol.447 (1), p.17-23

2012

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Platelet PI3Kβ and GSK3 regulate thrombus stability at a high shear rate

Blood, 2015-01, Vol.125 (5), p.881-888

2015

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Organismal roles for the PI3Kα and β isoforms: their specificity, redundancy or cooperation is context-dependent

Biochemical journal, 2021-03, Vol.478 (6), p.1199-1225

2021

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Class I PI 3-kinases signaling in platelet activation and thrombosis: PDK1/Akt/GSK3 axis and impact of PTEN and SHIP1

Advances in biological regulation, 2014-01, Vol.54, p.162-174

2014

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Phosphoinositide 3-kinases in platelets, thrombosis and therapeutics

Biochemical journal, 2020-11, Vol.477 (22), p.4327-4342

2020

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A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth

Blood, 2017-11, Vol.130 (18), p.2032-2042

2017

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Deficiency of Src homology 2 domain-containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth

The Journal of clinical investigation, 2007-04, Vol.117 (4), p.944-952

2007

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Deletion of the p110β isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo

Blood, 2010-03, Vol.115 (10), p.2008-2013

2010

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Platelets Are Critical Key Players in Sepsis

PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity

The lipid products of phosphoinositide 3-kinase isoforms in cancer and thrombosis

Role of oculocerebrorenal syndrome of Lowe (OCRL) protein in megakaryocyte maturation, platelet production and functions: a study in patients with Lowe syndrome

Platelet activation and prothrombotic properties in a mouse model of peritoneal sepsis

SHIP1 Controls Internal Platelet Contraction and αIIbβ3 Integrin Dynamics in Early Platelet Activation

Kinetics of mean platelet volume predicts mortality in patients with septic shock

Phosphoinositides take a central stage in regulating blood platelet production and function

Platelet P2Y1 receptor exhibits constitutive G protein signaling and β-arrestin 2 recruitment

Targeting Kinases in Cancer Therapies: Adverse Effects on Blood Platelets

Evolution of platelet activation parameters during septic shock in intensive care unit

The new tyrosine-kinase inhibitor and anticancer drug dasatinib reversibly affects platelet activation in vitro and in vivo

Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion

Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolism

Exploring the Role of PI3P in Platelets: Insights from a Novel External PI3P Pool

Platelet Versus Megakaryocyte: Who Is the Real Bandleader of Thromboinflammation in Sepsis?

G13 is an essential mediator of platelet activation in hemostasis and thrombosis

A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples

Platelet PI3Kβ and GSK3 regulate thrombus stability at a high shear rate

Organismal roles for the PI3Kα and β isoforms: their specificity, redundancy or cooperation is context-dependent

Class I PI 3-kinases signaling in platelet activation and thrombosis: PDK1/Akt/GSK3 axis and impact of PTEN and SHIP1

Phosphoinositide 3-kinases in platelets, thrombosis and therapeutics

A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth

Deficiency of Src homology 2 domain-containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth

Deletion of the p110β isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo

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