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Piezo1 ion channels inherently function as independent mechanotransducers

eLife, 2021-10, Vol.10

2021

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A cellular mechanism for age-induced itch

Science (American Association for the Advancement of Science), 2018-05, Vol.360 (6388), p.492-493

2018

Volltextzugriff (PDF)

Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension

eLife, 2015-12, Vol.4

2015

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The energetics of rapid cellular mechanotransduction

Biophysical journal, 2023-02, Vol.122 (3), p.89a-90a

2023

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Single residues in the outer pore of TRPV1 and TRPV3 have temperature-dependent conformations

PloS one, 2013-03, Vol.8 (3), p.e59593-e59593

2013

Volltextzugriff (PDF)

Touch, Tension, and Transduction – The Function and Regulation of Piezo Ion Channels

Trends in biochemical sciences (Amsterdam. Regular ed.), 2017-01, Vol.42 (1), p.57-71

2017

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Localized force application reveals mechanically sensitive domains of Piezo1

Nature communications, 2016-10, Vol.7 (1), p.12939-12939, Article 12939

2016

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Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (5), p.1626-1631

2009

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Inactivation Kinetics and Mechanical Gating of Piezo1 Ion Channels Depend on Subdomains within the Cap

Cell reports (Cambridge), 2020-01, Vol.30 (3), p.870-880.e2

2020

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The pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazole

PloS one, 2014, Vol.9 (9), p.e106776-e106776

2014

Volltextzugriff (PDF)

Balboa Binds to Pickpocket In Vivo and Is Required for Mechanical Nociception in Drosophila Larvae

Current biology, 2014-12, Vol.24 (24), p.2920-2925

2014

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Subconductance states add complexity to Piezo1 gating model

Trends in biochemical sciences (Amsterdam. Regular ed.), 2024-07, Vol.49 (7), p.567-568

2024

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Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (47), p.E5114-E5122

2014

Volltextzugriff (PDF)

Piezo proteins are pore-forming subunits of mechanically activated channels

Nature (London), 2012-03, Vol.483 (7388), p.176-181

2012

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Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization

Neuron (Cambridge, Mass.), 2017-04, Vol.94 (2), p.266-270.e3

2017

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Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels

Cell reports (Cambridge), 2017-06, Vol.19 (12), p.2572-2585

2017

Volltextzugriff (PDF)

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain

Nature neuroscience, 2010-06, Vol.13 (6), p.708-714

2010

Volltextzugriff (PDF)

Inactivation of Mechanically Activated Piezo1 Ion Channels Is Determined by the C-Terminal Extracellular Domain and the Inner Pore Helix

Cell reports (Cambridge), 2017-11, Vol.21 (9), p.2357-2366

2017

Volltextzugriff (PDF)

Temperature-activated ion channels in neural crest cells confer maternal fever-associated birth defects

Science signaling, 2017-10, Vol.10 (500)

2017

Volltextzugriff (PDF)

Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes

Cell reports (Cambridge), 2019-01, Vol.26 (5), p.1174-1188.e5

2019

Volltextzugriff (PDF)

Pore region of TRPV3 ion channel is specifically required for heat activation

Nature neuroscience, 2008-09, Vol.11 (9), p.1007-1013

2008

Volltextzugriff (PDF)

Physics of mechanotransduction by Piezo ion channels

The Journal of general physiology, 2022-07, Vol.154 (7), p.1

2022

Volltextzugriff (PDF)

The Energetics of Rapid Cellular Mechanotransduction

Biophysical journal, 2021-02, Vol.120 (3), p.234a-234a

2021

Volltextzugriff (PDF)

Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six

Neuron (Cambridge, Mass.), 2014-06, Vol.82 (5), p.1017-1031

2014

Volltextzugriff (PDF)

TRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity

Scientific reports, 2017-04, Vol.7 (1), p.549-10, Article 549

2017

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Piezo1 ion channels inherently function as independent mechanotransducers

A cellular mechanism for age-induced itch

Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension

The energetics of rapid cellular mechanotransduction

Single residues in the outer pore of TRPV1 and TRPV3 have temperature-dependent conformations

Touch, Tension, and Transduction – The Function and Regulation of Piezo Ion Channels

Localized force application reveals mechanically sensitive domains of Piezo1

Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4

Inactivation Kinetics and Mechanical Gating of Piezo1 Ion Channels Depend on Subdomains within the Cap

The pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazole

Balboa Binds to Pickpocket In Vivo and Is Required for Mechanical Nociception in Drosophila Larvae

Subconductance states add complexity to Piezo1 gating model

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

Piezo proteins are pore-forming subunits of mechanically activated channels

Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization

Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain

Inactivation of Mechanically Activated Piezo1 Ion Channels Is Determined by the C-Terminal Extracellular Domain and the Inner Pore Helix

Temperature-activated ion channels in neural crest cells confer maternal fever-associated birth defects

Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes

Pore region of TRPV3 ion channel is specifically required for heat activation

Physics of mechanotransduction by Piezo ion channels

The Energetics of Rapid Cellular Mechanotransduction

Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six

TRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity

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