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Chemically reactive intermediates and pulmonary xenobiotic toxicity

Pharmacological reviews, 1997-12, Vol.49 (4), p.297

Gram, T E

1997

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Metabolic activation and toxicity of some chemical agents to lung tissue and cells

Biochemical pharmacology, 1995-06, Vol.49 (12), p.1721-1727

Gram, Theodore E.

1995

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Stimulation of mouse heart and liver microsomal lipid peroxidation by anthracycline anticancer drugs: characterization and effects of reactive oxygen scavengers

The Journal of pharmacology and experimental therapeutics, 1983-09, Vol.226 (3), p.806

1983

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Enhancement of reactive oxygen-dependent mitochondrial membrane lipid peroxidation by the anticancer drug adriamycin

Biochemical pharmacology, 1985-01, Vol.34 (6), p.847-856

1985

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The metabolism of xenobiotics by certain extrahepatic organs and its relation to toxicity

Annual review of pharmacology and toxicology, 1986-01, Vol.26 (1), p.259-291

1986

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Pulmonary toxicity of 4-ipomeanol

Pharmacology & therapeutics (Oxford), 1989, Vol.43 (2), p.291-297

Gram, Theodore E.

1989

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A possible role for membrane lipid peroxidation in anthracycline nephrotoxicity

Biochemical pharmacology, 1986-12, Vol.35 (23), p.4327-4335

1986

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Distribution and disposition of platinum following intravenous administration of cis-diamminedichloroplatinum(II) (NSC 119875) to dogs

Cancer research (Chicago, Ill.), 1976-07, Vol.36 (7 PT 1), p.2340-2344

1976

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Selective induction of renal microsomal cytochrome P-450-linked monooxygenases by 1,1-dichloroethylene in mice

Biochemical pharmacology, 1984-06, Vol.33 (12), p.1951-1956

1984

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Studies on the interaction of bleomycin A2 with rat lung microsomes. I. Characterization of factors which influence bleomycin-mediated DNA chain breakage

The Journal of pharmacology and experimental therapeutics, 1982-04, Vol.221 (1), p.152

1982

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Studies on the Rate of Reduction of Hepatic Microsomal Cytochrome P-450 by Reduced Nicotinamide Adenine Dinucleotide Phosphate: Effect of Drug Substrates

Molecular pharmacology, 1969-03, Vol.5 (2), p.109-122

1969

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The distribution of the components of mixed-function oxidase between the rough and the smooth endoplasmic reticulum of liver cells

Biochemical journal, 1968-12, Vol.110 (3), p.407-412

1968

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Species and dose differences in the accumulation of imipramine by mammalian lungs

Drug metabolism and disposition, 1981-07, Vol.9 (4), p.322

1981

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The utility of changes in cardiac weight as an index of drug-induced cardiotoxicity

Journal of environmental pathology, toxicology and oncology, 1985-09, Vol.6 (1), p.57

1985

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Changes in Michaelis and Spectral Constants for Aniline in Hepatic Microsomes from Phenobarbital-Treated Rats

Molecular pharmacology, 1969-03, Vol.5 (2), p.131-136

1969

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Selective damage to nonciliated bronchiolar epithelial cells in relation to impairment of pulmonary monooxygenase activities by 1,1-dichloroethylene in mice

Toxicology and applied pharmacology, 1984-06, Vol.74 (2), p.201-213

1984

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A comparative study of the hepatic and pulmonary microsomal mixed-function oxidase systems in the rabbit

The Journal of pharmacology and experimental therapeutics, 1972-10, Vol.183 (1), p.206

1972

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A comparison of the pulmonary toxicity and chemotherapeutic activity of bleomycin-BAPP to bleomycin and pepleomycin

Cancer chemotherapy and pharmacology, 1984-01, Vol.12 (2), p.111-115

1984

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A comprehensive study of in vitro drug metabolism in several laboratory species

Drug metabolism and disposition, 1976-05, Vol.4 (3), p.203

1976

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Preparation of lung microsomes and a comparison of the distribution of enzymes between subcellular fractions of rabbit lung and liver

The Journal of pharmacology and experimental therapeutics, 1972-09, Vol.182 (3), p.474

1972

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Bleomycin-metal interaction: Ferrous iron-initiated chemiluminescence

Biochemical and biophysical research communications, 1983-04, Vol.112 (2), p.378-383

1983

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Studies on the in vitro interaction of mitomycin C, nitrofurantoin and paraquat with pulmonary microsomes : Stimulation of reactive oxygen-dependent lipid peroxidation

Biochemical pharmacology, 1982-03, Vol.31 (5), p.805-814

1982

Volltextzugriff (PDF)

Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells

Gram, T. E

1, 1993

Volltextzugriff (PDF)

Interaction of the oncolytic drug, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea with the mixed-function oxidase system in rats

Chemico-biological interactions, 1984-04, Vol.49 (1), p.105-119

1984

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Protection by Methylprednisolone against Butylated Hydroxytoluene-Induced Pulmonary Damage and Impairment of Microsomal Monooxygenase Activities in the Mouse: Lack of Effect on Fibrosis

Experimental lung research, 1986, Vol.10 (1), p.1-22

1986

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Chemically reactive intermediates and pulmonary xenobiotic toxicity

Metabolic activation and toxicity of some chemical agents to lung tissue and cells

Stimulation of mouse heart and liver microsomal lipid peroxidation by anthracycline anticancer drugs: characterization and effects of reactive oxygen scavengers

Enhancement of reactive oxygen-dependent mitochondrial membrane lipid peroxidation by the anticancer drug adriamycin

The metabolism of xenobiotics by certain extrahepatic organs and its relation to toxicity

Pulmonary toxicity of 4-ipomeanol

A possible role for membrane lipid peroxidation in anthracycline nephrotoxicity

Distribution and disposition of platinum following intravenous administration of cis-diamminedichloroplatinum(II) (NSC 119875) to dogs

Selective induction of renal microsomal cytochrome P-450-linked monooxygenases by 1,1-dichloroethylene in mice

Studies on the interaction of bleomycin A2 with rat lung microsomes. I. Characterization of factors which influence bleomycin-mediated DNA chain breakage

Studies on the Rate of Reduction of Hepatic Microsomal Cytochrome P-450 by Reduced Nicotinamide Adenine Dinucleotide Phosphate: Effect of Drug Substrates

The distribution of the components of mixed-function oxidase between the rough and the smooth endoplasmic reticulum of liver cells

Species and dose differences in the accumulation of imipramine by mammalian lungs

The utility of changes in cardiac weight as an index of drug-induced cardiotoxicity

Changes in Michaelis and Spectral Constants for Aniline in Hepatic Microsomes from Phenobarbital-Treated Rats

Selective damage to nonciliated bronchiolar epithelial cells in relation to impairment of pulmonary monooxygenase activities by 1,1-dichloroethylene in mice

A comparative study of the hepatic and pulmonary microsomal mixed-function oxidase systems in the rabbit

A comparison of the pulmonary toxicity and chemotherapeutic activity of bleomycin-BAPP to bleomycin and pepleomycin

A comprehensive study of in vitro drug metabolism in several laboratory species

Preparation of lung microsomes and a comparison of the distribution of enzymes between subcellular fractions of rabbit lung and liver

Bleomycin-metal interaction: Ferrous iron-initiated chemiluminescence

Studies on the in vitro interaction of mitomycin C, nitrofurantoin and paraquat with pulmonary microsomes : Stimulation of reactive oxygen-dependent lipid peroxidation

Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells

Interaction of the oncolytic drug, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea with the mixed-function oxidase system in rats

Protection by Methylprednisolone against Butylated Hydroxytoluene-Induced Pulmonary Damage and Impairment of Microsomal Monooxygenase Activities in the Mouse: Lack of Effect on Fibrosis

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