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The primary cilium: Its role as a tumor suppressor organelle

Biochemical pharmacology, 2020-05, Vol.175, p.113906-113906, Article 113906

2020

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The cholangiocyte primary cilium in health and disease

Biochimica et biophysica acta. Molecular basis of disease, 2018-04, Vol.1864 (4), p.1245-1253

2018

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HDAC6 Inhibition Restores Ciliary Expression and Decreases Tumor Growth

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (7), p.2259-2270

2013

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Hepatobiliary Cancers: Progress in Diagnosis, Pathogenesis, and Treatment

Technology in cancer research & treatment, 2022-01, Vol.21, p.15330338221097203-15330338221097203

2022

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The Chemosensory Function of Primary Cilia Regulates Cholangiocyte Migration, Invasion, and Tumor Growth

Hepatology (Baltimore, Md.), 2019-04, Vol.69 (4), p.1582-1598

2019

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Role of Histone Deacetylases in Carcinogenesis: Potential Role in Cholangiocarcinoma

Cells (Basel, Switzerland), 2020-03, Vol.9 (3), p.780

2020

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Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling

American journal of physiology: Gastrointestinal and liver physiology, 2013-06, Vol.304 (11), p.G1013-G1024

2013

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Primary Cilia in Tumor Biology: The Primary Cilium as a Therapeutic Target in Cholangiocarcinoma

Current drug targets, 2017-01, Vol.18 (8), p.958-963

2017

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Short-Chain Fatty Acid Butyrate Induces Cilia Formation and Potentiates the Effects of HDAC6 Inhibitors in Cholangiocarcinoma Cells

Frontiers in cell and developmental biology, 2022-01, Vol.9, p.809382

2022

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Combination of a Histone Deacetylase 6 Inhibitor and a Somatostatin Receptor Agonist Synergistically Reduces Hepatorenal Cystogenesis in an Animal Model of Polycystic Liver Disease

The American journal of pathology, 2018-04, Vol.188 (4), p.981-994

2018

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Tiny sentinels: how cilia guard the kidneys in ischaemia–reperfusion injury

The Journal of physiology, 2024-10, Vol.602 (19), p.4703-4704

2024

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NAMPT Overexpression Drives Cell Growth in Polycystic Liver Disease through Mitochondrial Metabolism Regulation

The American journal of pathology, 2024-08, Vol.194 (8), p.1528-1537

2024

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Role of Glucose Metabolism Reprogramming in the Pathogenesis of Cholangiocarcinoma

Frontiers in medicine, 2020-04, Vol.7, p.113-113

2020

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Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion

Proceedings of the National Academy of Sciences - PNAS, 2007-11, Vol.104 (48), p.19138-19143

2007

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Targeting IRES-Mediated p53 Synthesis for Cancer Diagnosis and Therapeutics

International journal of molecular sciences, 2017-01, Vol.18 (1), p.93-93

2017

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HDAC6 Is Overexpressed in Cystic Cholangiocytes and Its Inhibition Reduces Cystogenesis

The American journal of pathology, 2014-03, Vol.184 (3), p.600-608

2014

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Prognostic value of circulating tumor cells in nonmuscle invasive bladder cancer: a CellSearch analysis

Annals of oncology, 2012-09, Vol.23 (9), p.2352-2356

2012

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Circulating tumor cells (CTCs) in metastatic breast cancer (MBC): prognosis, drug resistance and phenotypic characterization

Annals of oncology, 2011-01, Vol.22 (1), p.86-92

2011

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The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD)

Hepatology (Baltimore, Md.), 2009-01, Vol.49 (1), p.160-174

2009

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Detecting the disappearance of RAS-mutant clones in the plasma of patients with RAS-mutant mCRC to select patient candidates for anti-EGFR treatment and to monitor resistance to treatment

Annals of oncology, 2019-07, Vol.30, p.iv38-iv38

2019

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The NAMPT Inhibitor FK866 in Combination with Cisplatin Reduces Cholangiocarcinoma Cells Growth

Cells (Basel, Switzerland), 2023-02, Vol.12 (5), p.775

2023

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Activation of Trpv4 Reduces the Hyperproliferative Phenotype of Cystic Cholangiocytes From an Animal Model of ARPKD

Gastroenterology (New York, N.Y. 1943), 2010-07, Vol.139 (1), p.304-314.e2

2010

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Extracellular vesicles as therapeutic carriers of microRNAs for cholangiocarcinoma

Hepatology (Baltimore, Md.), 2017-02, Vol.65 (2), p.404-406

Gradilone, Sergio A.

2017

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2194 Isolation of circulating tumor cells with stem-like features in metastatic colorectal cancer

European journal of cancer (1990), 2015-09, Vol.51, p.S398-S398

2015

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Cilia and Cancer: From Molecular Genetics to Therapeutic Strategies

Genes, 2023-07, Vol.14 (7), p.1428

2023

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The primary cilium: Its role as a tumor suppressor organelle

The cholangiocyte primary cilium in health and disease

HDAC6 Inhibition Restores Ciliary Expression and Decreases Tumor Growth

Hepatobiliary Cancers: Progress in Diagnosis, Pathogenesis, and Treatment

The Chemosensory Function of Primary Cilia Regulates Cholangiocyte Migration, Invasion, and Tumor Growth

Role of Histone Deacetylases in Carcinogenesis: Potential Role in Cholangiocarcinoma

Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling

Primary Cilia in Tumor Biology: The Primary Cilium as a Therapeutic Target in Cholangiocarcinoma

Short-Chain Fatty Acid Butyrate Induces Cilia Formation and Potentiates the Effects of HDAC6 Inhibitors in Cholangiocarcinoma Cells

Combination of a Histone Deacetylase 6 Inhibitor and a Somatostatin Receptor Agonist Synergistically Reduces Hepatorenal Cystogenesis in an Animal Model of Polycystic Liver Disease

Tiny sentinels: how cilia guard the kidneys in ischaemia–reperfusion injury

NAMPT Overexpression Drives Cell Growth in Polycystic Liver Disease through Mitochondrial Metabolism Regulation

Role of Glucose Metabolism Reprogramming in the Pathogenesis of Cholangiocarcinoma

Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion

Targeting IRES-Mediated p53 Synthesis for Cancer Diagnosis and Therapeutics

HDAC6 Is Overexpressed in Cystic Cholangiocytes and Its Inhibition Reduces Cystogenesis

Prognostic value of circulating tumor cells in nonmuscle invasive bladder cancer: a CellSearch analysis

Circulating tumor cells (CTCs) in metastatic breast cancer (MBC): prognosis, drug resistance and phenotypic characterization

The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD)

Detecting the disappearance of RAS-mutant clones in the plasma of patients with RAS-mutant mCRC to select patient candidates for anti-EGFR treatment and to monitor resistance to treatment

The NAMPT Inhibitor FK866 in Combination with Cisplatin Reduces Cholangiocarcinoma Cells Growth

Activation of Trpv4 Reduces the Hyperproliferative Phenotype of Cystic Cholangiocytes From an Animal Model of ARPKD

Extracellular vesicles as therapeutic carriers of microRNAs for cholangiocarcinoma

2194 Isolation of circulating tumor cells with stem-like features in metastatic colorectal cancer

Cilia and Cancer: From Molecular Genetics to Therapeutic Strategies

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