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On the Mechanisms of Biliary Flux

Hepatology (Baltimore, Md.), 2021-12, Vol.74 (6), p.3497-3512

2021

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Familial cholestasis: Progressive familial intrahepatic cholestasis, benign recurrent intrahepatic cholestasis and intrahepatic cholestasis of pregnancy

Baillière's best practice & research. Clinical gastroenterology, 2010-10, Vol.24 (5), p.541-553

2010

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Heteromeric Interactions Required for Abundance and Subcellular Localization of Human CDC50 Proteins and Class 1 P4-ATPases

The Journal of biological chemistry, 2010-12, Vol.285 (51), p.40088-40096

2010

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Targeting the Four Pillars of Enterohepatic Bile Salt Cycling; Lessons From Genetics and Pharmacology

Hepatology (Baltimore, Md.), 2021-06, Vol.73 (6), p.2577-2585

2021

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Rescue of defective ATP8B1 trafficking by CFTR correctors as a therapeutic strategy for familial intrahepatic cholestasis

Journal of hepatology, 2016-06, Vol.64 (6), p.1339-1347

2016

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Monitoring bile acid transport in single living cells using a genetically encoded Förster resonance energy transfer sensor

Hepatology (Baltimore, Md.), 2013-02, Vol.57 (2), p.740-752

2013

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Natural killer T cells in adipose tissue prevent insulin resistance

The Journal of clinical investigation, 2012-09, Vol.122 (9), p.3343-3354

2012

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Bile salt signaling and bile salt-based therapies in cardiometabolic disease

Clinical science (1979), 2024-01, Vol.138 (1), p.1-21

2024

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Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β

Cellular and molecular gastroenterology and hepatology, 2018-01, Vol.5 (3), p.223-237

2018

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Preclinical targeting of liver fibrosis with a 89Zr-labeled Fibrobody® directed against platelet derived growth factor receptor-β

European journal of nuclear medicine and molecular imaging, 2024-10, Vol.51 (12), p.3545-3558

2024

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Blocking Sodium‐Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice

Hepatology (Baltimore, Md.), 2020-01, Vol.71 (1), p.247-258

2020

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Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na+‐Taurocholate Cotransporting Polypeptide

Hepatology communications, 2018-12, Vol.2 (12), p.1550-1566

2018

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On the role of IgG4 in inflammatory conditions: lessons for IgG4-related disease

Biochimica et biophysica acta. Molecular basis of disease, 2018-04, Vol.1864 (4), p.1401-1409

2018

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Bioengineered bile ducts recapitulate key cholangiocyte functions

Biofabrication, 2018-06, Vol.10 (3), p.034103-034103

2018

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The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction

Journal of human genetics, 2018-05, Vol.63 (5), p.683-686

2018

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Molecular regulation of the hepatic bile acid uptake transporter and HBV entry receptor NTCP

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2021-08, Vol.1866 (8), p.158960, Article 158960

2021

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Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice

Hepatology (Baltimore, Md.), 2017-11, Vol.66 (5), p.1631-1643

2017

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Bile Acid Uptake Transporters as Targets for Therapy

Digestive diseases (Basel), 2017-01, Vol.35 (3), p.251-258

2017

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Impaired uptake of conjugated bile acids and hepatitis b virus pres1‐binding in na+‐taurocholate cotransporting polypeptide knockout mice

Hepatology (Baltimore, Md.), 2015-07, Vol.62 (1), p.207-219

2015

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Inhibition of hepatic bile salt uptake by Bulevirtide reduces atherosclerosis in Oatp1a1−/−Ldlr−/− mice

Journal of lipid research, 2024-08, Vol.65 (8), p.100594, Article 100594

2024

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Knockout of the primary sclerosing cholangitis‐risk gene Fut2 causes liver disease in mice

Hepatology (Baltimore, Md.), 2017-08, Vol.66 (2), p.542-554

2017

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Inhibition of autotaxin by bile salts and bile salt-like molecules increases its expression by feedback regulation

Biochimica et biophysica acta. Molecular basis of disease, 2021-11, Vol.1867 (11), p.166239-166239, Article 166239

2021

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Mechanistic insights into the inhibition of NTCP by myrcludex B

JHEP reports, 2019-10, Vol.1 (4), p.278-285

2019

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Analysis of aberrant pre‐messenger RNA splicing resulting from mutations in ATP8B1 and efficient in vitro rescue by adapted U1 small nuclear RNA

Hepatology (Baltimore, Md.), 2015-04, Vol.61 (4), p.1382-1391

2015

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Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice

JHEP reports, 2022-11, Vol.4 (11), p.100573-100573, Article 100573

2022

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On the Mechanisms of Biliary Flux

Familial cholestasis: Progressive familial intrahepatic cholestasis, benign recurrent intrahepatic cholestasis and intrahepatic cholestasis of pregnancy

Heteromeric Interactions Required for Abundance and Subcellular Localization of Human CDC50 Proteins and Class 1 P4-ATPases

Targeting the Four Pillars of Enterohepatic Bile Salt Cycling; Lessons From Genetics and Pharmacology

Rescue of defective ATP8B1 trafficking by CFTR correctors as a therapeutic strategy for familial intrahepatic cholestasis

Monitoring bile acid transport in single living cells using a genetically encoded Förster resonance energy transfer sensor

Natural killer T cells in adipose tissue prevent insulin resistance

Bile salt signaling and bile salt-based therapies in cardiometabolic disease

Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β

Preclinical targeting of liver fibrosis with a 89Zr-labeled Fibrobody® directed against platelet derived growth factor receptor-β

Blocking Sodium‐Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice

Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na+‐Taurocholate Cotransporting Polypeptide

On the role of IgG4 in inflammatory conditions: lessons for IgG4-related disease

Bioengineered bile ducts recapitulate key cholangiocyte functions

The somatic FAH C.1061C>A change counteracts the frequent FAH c.1062+5G>A mutation and permits U1snRNA-based splicing correction

Molecular regulation of the hepatic bile acid uptake transporter and HBV entry receptor NTCP

Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice

Bile Acid Uptake Transporters as Targets for Therapy

Impaired uptake of conjugated bile acids and hepatitis b virus pres1‐binding in na+‐taurocholate cotransporting polypeptide knockout mice

Inhibition of hepatic bile salt uptake by Bulevirtide reduces atherosclerosis in Oatp1a1−/−Ldlr−/− mice

Knockout of the primary sclerosing cholangitis‐risk gene Fut2 causes liver disease in mice

Inhibition of autotaxin by bile salts and bile salt-like molecules increases its expression by feedback regulation

Mechanistic insights into the inhibition of NTCP by myrcludex B

Analysis of aberrant pre‐messenger RNA splicing resulting from mutations in ATP8B1 and efficient in vitro rescue by adapted U1 small nuclear RNA

Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice

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