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Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Angewandte Chemie International Edition, 2022-01, Vol.61 (2), p.e202111291-n/a

2022

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Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers

International journal of pharmaceutics, 2022-11, Vol.628, p.122238-122238, Article 122238

2022

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Extension of hydrogen borrowing alkylation reactions for the total synthesis of (−)-γ-lycorane

Chemical communications (Cambridge, England), 2022-04, Vol.58 (32), p.4966-4968

2022

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An Alternative Focus for Route Design for the Synthesis of Antibody–Drug Conjugate Payloads

Journal of organic chemistry, 2019-04, Vol.84 (8), p.4830-4836

2019

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Palladium-catalyzed hydroacyloxylation of ynamides

Chemical communications (Cambridge, England), 2012-02, Vol.48 (10), p.1505-1507

2012

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Development and Scale-up of a Biocatalytic Process To Form a Chiral Sulfoxide

Organic process research & development, 2017-01, Vol.21 (1), p.107-113

2017

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Organic Solvent Nanofiltration in Pharmaceutical Applications

Organic process research & development, 2024-04, Vol.28 (4), p.891-923

2024

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Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Angewandte Chemie International Edition, 2021-03, Vol.60 (13), p.6981-6985

International ed. in English, 2021

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Synthesis of Sulfur-Substituted Bicyclo[1.1.1]pentanes by Iodo-Sulfenylation of [1.1.1]Propellane

Organic letters, 2022-09, Vol.24 (38), p.7015-7020

2022

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Development and Scale-up of a Route to ATR Inhibitor AZD6738

Organic process research & development, 2019-07, Vol.23 (7), p.1333-1342

2019

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Total Synthesis of (+)-Apiosporamide: Assignment of Relative and Absolute Configuration

Angewandte Chemie (International ed.), 2005-10, Vol.44 (41), p.6715-6718

2005

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Palladium-catalyzed hydroacyloxylation of ynamides

Chemical communications (Cambridge, England), 2012, Vol.48 (10), p.1505-1507

2012

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The Development of a Dimroth Rearrangement Route to AZD8931

Organic process research & development, 2017-03, Vol.21 (3), p.336-345

2017

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Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Angewandte Chemie, 2021-03, Vol.133 (13), p.7057-7061

2021

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Payloads for Antibody–Drug Conjugates

Organic process research & development, 2022-08, Vol.26 (8), p.2121-2123

2022

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Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Angewandte Chemie, 2022-01, Vol.134 (2), p.n/a

2022

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Electrophilic Activation of 1.1.1Propellane for the Synthesis of Nitrogen-Substituted Bicyclo1.1.1pentanes

Angewandte Chemie International Edition, 2022-01, Vol.61 (2), p.e202111291

2022

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Electrophilic Activation of Propellane for the Synthesis of Nitrogen‐Substituted Bicyclopentanes

Angewandte Chemie International Edition, 2022-01, Vol.61 (2)

International ed. in English, 2022

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CC/B–N substitution in five membered heterocycles. A computational analysis

New journal of chemistry, 2017-05, Vol.41 (9), p.3619-3633

2017

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Route Design and Scale-Up of a Topoisomerase I Inhibitor Antibody–Drug Conjugate Payload

Organic process research & development, 2024-06, Vol.28 (6), p.2355-2366

2024

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C&z.dbd;C/B-N substitution in five membered heterocycles. A computational analysisElectronic supplementary information (ESI) available: Table S1 containing HOMA parameters for model systems, Fig. S1 showing dipole moments of azaboroles, a short section and Table S2 for effect of solvent on the relative stability of azaboroles, Table S3 containing correlation matrix for NICS values, Fig. S2 showing variation of NICS values with distance from the ring centre, Table S4 containing atomic charges and

2017-05

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Horner–Wadsworth–Emmons olefination of proteins and glycoproteins

Nature Synthesis, 2024-08, Vol.3 (8), p.976-985

2024

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An Enantiocontrolled Approach for the Synthesis of Chiral 3,5-Disubstituted 2(1H)-pyridinones

Heterocycles, 2006-02, Vol.67 (2), p.555

2006

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Electrophilic Activation of Propellane for the Synthesis of Nitrogen‐Substituted Bicyclopentanes

Angewandte Chemie, 2022-01, Vol.134 (2)

2022

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Palladium-catalyzed hydroacyloxylation of ynamidesThis article is part of the ChemComm Emerging Investigators 2012 themed issue.Electronic supplementary information (ESI) available: Experimental procedures, spectroscopic data for new compounds. CCDC 828301. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c1cc13595c

2012-01

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Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers

Extension of hydrogen borrowing alkylation reactions for the total synthesis of (−)-γ-lycorane

An Alternative Focus for Route Design for the Synthesis of Antibody–Drug Conjugate Payloads

Palladium-catalyzed hydroacyloxylation of ynamides

Development and Scale-up of a Biocatalytic Process To Form a Chiral Sulfoxide

Organic Solvent Nanofiltration in Pharmaceutical Applications

Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Synthesis of Sulfur-Substituted Bicyclo[1.1.1]pentanes by Iodo-Sulfenylation of [1.1.1]Propellane

Development and Scale-up of a Route to ATR Inhibitor AZD6738

Total Synthesis of (+)-Apiosporamide: Assignment of Relative and Absolute Configuration

Palladium-catalyzed hydroacyloxylation of ynamides

The Development of a Dimroth Rearrangement Route to AZD8931

Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Payloads for Antibody–Drug Conjugates

Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Electrophilic Activation of 1.1.1Propellane for the Synthesis of Nitrogen-Substituted Bicyclo1.1.1pentanes

Electrophilic Activation of Propellane for the Synthesis of Nitrogen‐Substituted Bicyclopentanes

CC/B–N substitution in five membered heterocycles. A computational analysis

Route Design and Scale-Up of a Topoisomerase I Inhibitor Antibody–Drug Conjugate Payload

Horner–Wadsworth–Emmons olefination of proteins and glycoproteins

An Enantiocontrolled Approach for the Synthesis of Chiral 3,5-Disubstituted 2(1H)-pyridinones

Electrophilic Activation of Propellane for the Synthesis of Nitrogen‐Substituted Bicyclopentanes

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