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An Alternative Focus for Route Design for the Synthesis of Antibody–Drug Conjugate Payloads

Journal of organic chemistry, 2019-04, Vol.84 (8), p.4830-4836

2019

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CC/B–N substitution in five membered heterocycles. A computational analysis

New journal of chemistry, 2017-05, Vol.41 (9), p.3619-3633

2017

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C&z.dbd;C/B-N substitution in five membered heterocycles. A computational analysisElectronic supplementary information (ESI) available: Table S1 containing HOMA parameters for model systems, Fig. S1 showing dipole moments of azaboroles, a short section and Table S2 for effect of solvent on the relative stability of azaboroles, Table S3 containing correlation matrix for NICS values, Fig. S2 showing variation of NICS values with distance from the ring centre, Table S4 containing atomic charges and

2017-05

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ChemInform Abstract: Palladium-Catalyzed Hydroacyloxylation of Ynamides

ChemInform, 2012-06, Vol.43 (26), p.no-no

2012

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ChemInform Abstract: Rhodium-Catalyzed [2 + 2] Cycloaddition of Ynamides with Nitroalkenes

ChemInform, 2013-01, Vol.44 (5), p.no-no

2013

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ChemInform Abstract: Total Synthesis of Cytotoxic Sponge Alkaloids Hachijodines F and G

ChemInform, 2002-07, Vol.33 (30), p.no-no

2002

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Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers

International journal of pharmaceutics, 2022-11, Vol.628, p.122238-122238, Article 122238

2022

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Development and Scale-up of a Biocatalytic Process To Form a Chiral Sulfoxide

Organic process research & development, 2017-01, Vol.21 (1), p.107-113

2017

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Development and Scale-up of a Route to ATR Inhibitor AZD6738

Organic process research & development, 2019-07, Vol.23 (7), p.1333-1342

2019

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Development of a Continuous Flow Sulfoxide Imidation Protocol Using Azide Sources under Superacidic Conditions

Organic process research & development, 2015-08, Vol.19 (8), p.1062-1067

2015

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The Development of a Dimroth Rearrangement Route to AZD8931

Organic process research & development, 2017-03, Vol.21 (3), p.336-345

2017

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Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Angewandte Chemie, 2022-01, Vol.134 (2), p.n/a

2022

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Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Angewandte Chemie International Edition, 2022-01, Vol.61 (2), p.e202111291-n/a

2022

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Electrophilic Activation of 1.1.1Propellane for the Synthesis of Nitrogen-Substituted Bicyclo1.1.1pentanes

Angewandte Chemie International Edition, 2022-01, Vol.61 (2), p.e202111291

2022

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Electrophilic Activation of Propellane for the Synthesis of Nitrogen‐Substituted Bicyclopentanes

Angewandte Chemie International Edition, 2022-01, Vol.61 (2)

International ed. in English, 2022

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Electrophilic Activation of Propellane for the Synthesis of Nitrogen‐Substituted Bicyclopentanes

Angewandte Chemie, 2022-01, Vol.134 (2)

2022

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An Enantiocontrolled Approach for the Synthesis of Chiral 3,5-Disubstituted 2(1H)-pyridinones

Heterocycles, 2006-02, Vol.67 (2), p.555

2006

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An Enantiocontrolled Approach for the Synthesis of Chiral 3,5-Disubstituted 2(1H)-Pyridinones

ChemInform, 2006-07, Vol.37 (29), p.no-no

2006

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Extension of hydrogen borrowing alkylation reactions for the total synthesis of (−)-γ-lycorane

Chemical communications (Cambridge, England), 2022-04, Vol.58 (32), p.4966-4968

2022

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Galactose Oxidase Enables Modular Assembly of Conjugates from Native Antibodies with High Drug‐to‐Antibody Ratios

ChemSusChem, 2022-05, Vol.15 (9), p.e202102592-n/a

2022

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Horner–Wadsworth–Emmons olefination of proteins and glycoproteins

Nature Synthesis, 2024-08, Vol.3 (8), p.976-985

2024

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Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Angewandte Chemie, 2021-03, Vol.133 (13), p.7057-7061

2021

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Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Angewandte Chemie International Edition, 2021-03, Vol.60 (13), p.6981-6985

International ed. in English, 2021

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Organic Solvent Nanofiltration in Pharmaceutical Applications

Organic process research & development, 2024-04, Vol.28 (4), p.891-923

2024

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Palladium-catalyzed hydroacyloxylation of ynamides

Chemical communications (Cambridge, England), 2012-02, Vol.48 (10), p.1505-1507

2012

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An Alternative Focus for Route Design for the Synthesis of Antibody–Drug Conjugate Payloads

CC/B–N substitution in five membered heterocycles. A computational analysis

ChemInform Abstract: Palladium-Catalyzed Hydroacyloxylation of Ynamides

ChemInform Abstract: Rhodium-Catalyzed [2 + 2] Cycloaddition of Ynamides with Nitroalkenes

ChemInform Abstract: Total Synthesis of Cytotoxic Sponge Alkaloids Hachijodines F and G

Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers

Development and Scale-up of a Biocatalytic Process To Form a Chiral Sulfoxide

Development and Scale-up of a Route to ATR Inhibitor AZD6738

Development of a Continuous Flow Sulfoxide Imidation Protocol Using Azide Sources under Superacidic Conditions

The Development of a Dimroth Rearrangement Route to AZD8931

Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Electrophilic Activation of 1.1.1Propellane for the Synthesis of Nitrogen-Substituted Bicyclo1.1.1pentanes

Electrophilic Activation of Propellane for the Synthesis of Nitrogen‐Substituted Bicyclopentanes

Electrophilic Activation of Propellane for the Synthesis of Nitrogen‐Substituted Bicyclopentanes

An Enantiocontrolled Approach for the Synthesis of Chiral 3,5-Disubstituted 2(1H)-pyridinones

An Enantiocontrolled Approach for the Synthesis of Chiral 3,5-Disubstituted 2(1H)-Pyridinones

Extension of hydrogen borrowing alkylation reactions for the total synthesis of (−)-γ-lycorane

Galactose Oxidase Enables Modular Assembly of Conjugates from Native Antibodies with High Drug‐to‐Antibody Ratios

Horner–Wadsworth–Emmons olefination of proteins and glycoproteins

Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Organic Solvent Nanofiltration in Pharmaceutical Applications

Palladium-catalyzed hydroacyloxylation of ynamides

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