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Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Angewandte Chemie (International ed.), 2022-01, Vol.61 (2), p.e202111291-n/a

2022

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Organic Solvent Nanofiltration in Pharmaceutical Applications

Organic process research & development, 2024-04, Vol.28 (4), p.891-923

2024

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Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Angewandte Chemie (International ed.), 2021-03, Vol.60 (13), p.6981-6985

International ed. in English, 2021

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Extension of hydrogen borrowing alkylation reactions for the total synthesis of (−)-γ-lycorane

Chemical communications (Cambridge, England), 2022-04, Vol.58 (32), p.4966-4968

2022

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Synthesis of Sulfur-Substituted Bicyclo[1.1.1]pentanes by Iodo-Sulfenylation of [1.1.1]Propellane

Organic letters, 2022-09, Vol.24 (38), p.7015-7020

2022

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An Alternative Focus for Route Design for the Synthesis of Antibody–Drug Conjugate Payloads

Journal of organic chemistry, 2019-04, Vol.84 (8), p.4830-4836

2019

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Palladium-catalyzed hydroacyloxylation of ynamides

Chemical communications (Cambridge, England), 2012-02, Vol.48 (10), p.1505-1507

2012

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Development and Scale-up of a Route to ATR Inhibitor AZD6738

Organic process research & development, 2019-07, Vol.23 (7), p.1333-1342

2019

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Development and Scale-up of a Biocatalytic Process To Form a Chiral Sulfoxide

Organic process research & development, 2017-01, Vol.21 (1), p.107-113

2017

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Palladium-catalyzed hydroacyloxylation of ynamides

Chemical communications (Cambridge, England), 2012, Vol.48 (10), p.1505-1507

2012

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The Development of a Dimroth Rearrangement Route to AZD8931

Organic process research & development, 2017-03, Vol.21 (3), p.336-345

2017

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Rhodium-Catalyzed [2 + 2] Cycloaddition of Ynamides with Nitroalkenes

Organic letters, 2012-09, Vol.14 (18), p.4934-4937

2012

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Total Synthesis of (+)-Apiosporamide: Assignment of Relative and Absolute Configuration

Angewandte Chemie (International ed.), 2005-10, Vol.44 (41), p.6715-6718

2005

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Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Angewandte Chemie, 2021-03, Vol.133 (13), p.7057-7061

2021

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Payloads for Antibody–Drug Conjugates

Organic process research & development, 2022-08, Vol.26 (8), p.2121-2123

2022

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Synthesis of Excitatory Amino Acid Analogues

Synlett, 2006-09, Vol.2006 (15), p.2407-2410

2006

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Total synthesis of cytotoxic sponge alkaloids hachijodines F and G

Tetrahedron, 2003-03, Vol.59 (10), p.1719-1729

2003

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Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Angewandte Chemie, 2022-01, Vol.134 (2), p.n/a

2022

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Electrophilic Activation of Propellane for the Synthesis of Nitrogen‐Substituted Bicyclopentanes

Angewandte Chemie International Edition, 2022-01, Vol.61 (2)

International ed. in English, 2022

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CC/B–N substitution in five membered heterocycles. A computational analysis

New journal of chemistry, 2017-05, Vol.41 (9), p.3619-3633

2017

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Route Design and Scale-Up of a Topoisomerase I Inhibitor Antibody–Drug Conjugate Payload

Organic process research & development, 2024-06, Vol.28 (6), p.2355-2366

2024

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Trimethylsilyl Trifluoromethanesulfonate (TMSOTf)

Synlett, 2003-09, Vol.2003 (12), p.1940-1941

Goundry, William R.

2003

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Galactose Oxidase Enables Modular Assembly of Conjugates from Native Antibodies with High Drug‐to‐Antibody Ratios

ChemSusChem, 2022-05, Vol.15 (9), p.e202102592-n/a

2022

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C&z.dbd;C/B-N substitution in five membered heterocycles. A computational analysisElectronic supplementary information (ESI) available: Table S1 containing HOMA parameters for model systems, Fig. S1 showing dipole moments of azaboroles, a short section and Table S2 for effect of solvent on the relative stability of azaboroles, Table S3 containing correlation matrix for NICS values, Fig. S2 showing variation of NICS values with distance from the ring centre, Table S4 containing atomic charges and

2017-05

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Development of a Continuous Flow Sulfoxide Imidation Protocol Using Azide Sources under Superacidic Conditions

Organic process research & development, 2015-08, Vol.19 (8), p.1062-1067

2015

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Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Organic Solvent Nanofiltration in Pharmaceutical Applications

Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Extension of hydrogen borrowing alkylation reactions for the total synthesis of (−)-γ-lycorane

Synthesis of Sulfur-Substituted Bicyclo[1.1.1]pentanes by Iodo-Sulfenylation of [1.1.1]Propellane

An Alternative Focus for Route Design for the Synthesis of Antibody–Drug Conjugate Payloads

Palladium-catalyzed hydroacyloxylation of ynamides

Development and Scale-up of a Route to ATR Inhibitor AZD6738

Development and Scale-up of a Biocatalytic Process To Form a Chiral Sulfoxide

Palladium-catalyzed hydroacyloxylation of ynamides

The Development of a Dimroth Rearrangement Route to AZD8931

Rhodium-Catalyzed [2 + 2] Cycloaddition of Ynamides with Nitroalkenes

Total Synthesis of (+)-Apiosporamide: Assignment of Relative and Absolute Configuration

Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Payloads for Antibody–Drug Conjugates

Synthesis of Excitatory Amino Acid Analogues

Total synthesis of cytotoxic sponge alkaloids hachijodines F and G

Electrophilic Activation of [1.1.1]Propellane for the Synthesis of Nitrogen‐Substituted Bicyclo[1.1.1]pentanes

Electrophilic Activation of Propellane for the Synthesis of Nitrogen‐Substituted Bicyclopentanes

CC/B–N substitution in five membered heterocycles. A computational analysis

Route Design and Scale-Up of a Topoisomerase I Inhibitor Antibody–Drug Conjugate Payload

Trimethylsilyl Trifluoromethanesulfonate (TMSOTf)

Galactose Oxidase Enables Modular Assembly of Conjugates from Native Antibodies with High Drug‐to‐Antibody Ratios

Development of a Continuous Flow Sulfoxide Imidation Protocol Using Azide Sources under Superacidic Conditions

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