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Alzheimer‐like pathology in trisomy 21 cerebral organoids amenable to pharmacological inhibition reveals BACE2 as a gene‐dose‐sensitive AD‐suppressor in human brain

Alzheimer's & dementia, 2020-12, Vol.16, p.n/a

2020

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Alzheimer‐like pathology in trisomy 21 cerebral organoids amenable to pharmacological inhibition reveals BACE2 as a gene‐dose‐sensitive AD‐suppressor in human brain: Development of new models and analysis methods: Multisystem platform models of ADRD

Alzheimer's & dementia, 2020-12, Vol.16 (S2)

2020

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Correction: Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

Molecular psychiatry, 2021-10, Vol.26 (10), p.5789-5789

2021

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Modeling Down syndrome in cells: From stem cells to organoids

Progress in brain research, 2020, Vol.251, p.55-90

2020

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Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels

EBioMedicine, 2023-08, Vol.94, p.104692-104692, Article 104692

2023

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Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levelsResearch in context

EBioMedicine, 2023-08, Vol.94, p.104692

2023

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Reasons for Slimming and Weight Loss

Facet Theory, p.245-259

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Attitudes towards feminism predict susceptibility to feminism‐related fake news

Applied cognitive psychology, 2021-09, Vol.35 (5), p.1182-1192

2021

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Seven newly identified loci for autoimmune thyroid disease

Human molecular genetics, 2012-12, Vol.21 (23), p.5202-5208

2012

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How has COVID-19 lockdown impacted smoking? A thematic analysis of written accounts from UK smokers

Psychology & health, 2022, Vol.37 (1), p.17-33

2022

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Haplotype tagging for the identification of common disease genes

Nature genetics, 2001-10, Vol.29 (2), p.233-237

2001

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CD226 Gly307Ser association with multiple autoimmune diseases

Genes and immunity, 2009-01, Vol.10 (1), p.5-10

2009

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Duplex ultrasonography, magnetic resonance angiography, and computed tomography angiography for diagnosis and assessment of symptomatic, lower limb peripheral arterial disease: systematic review

BMJ (British Medical Journal), 2007-06, Vol.334 (7606), p.1257-1261

International edition, 2007

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Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2‑((4-(Benzo[d]thiazol-5-ylamino)-6‑(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases

Journal of medicinal chemistry, 2019-07, Vol.62 (14), p.6482-6494

2019

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Tumor Necrosis Factor-α-converting Enzyme (ADAM17) Mediates the Cleavage and Shedding of Fractalkine (CX3CL1)

The Journal of biological chemistry, 2001-10, Vol.276 (41), p.37993-38001

2001

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Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS)

Arthritis research & therapy, 2018-07, Vol.20 (1), p.147-11, Article 147

2018

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The predictors of and reasons for non-adherence in an observational cohort of patients with rheumatoid arthritis commencing methotrexate

Rheumatology (Oxford, England), 2020-01, Vol.59 (1), p.213-223

2020

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Rates and predictors of methotrexate-related adverse events in patients with early rheumatoid arthritis: results from a nationwide UK study

Rheumatology (Oxford, England), 2022-10, Vol.61 (10), p.3930-3938

2022

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Is the relationship between deprivation and outcomes in rheumatoid arthritis mediated by body mass index? A longitudinal cohort study

Rheumatology (Oxford, England), 2023-07, Vol.62 (7), p.2394-2401

2023

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Nurse-led group consultation intervention reduces depressive symptoms in men with localised prostate cancer: a cluster randomised controlled trial

BMC cancer, 2016-08, Vol.16 (1), p.637-637, Article 637

2016

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Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor

European journal of human genetics : EJHG, 2009-10, Vol.17 (10), p.1309-1313

2009

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Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

Nature genetics, 2012-01, Vol.44 (1), p.3-5

2012

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The potential yield of active play in the prevention of cancer

International journal of play, 2017-01, Vol.6 (1), p.78-84

2017

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Sepsis in Wales on the general wards: results of a feasibility pilot

British journal of anaesthesia : BJA, 2015-06, Vol.114 (6), p.1000-1001

2015

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Alzheimer‐like pathology in trisomy 21 cerebral organoids amenable to pharmacological inhibition reveals BACE2 as a gene‐dose‐sensitive AD‐suppressor in human brain

Alzheimer‐like pathology in trisomy 21 cerebral organoids amenable to pharmacological inhibition reveals BACE2 as a gene‐dose‐sensitive AD‐suppressor in human brain: Development of new models and analysis methods: Multisystem platform models of ADRD

Correction: Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

Modeling Down syndrome in cells: From stem cells to organoids

Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels

Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levelsResearch in context

Reasons for Slimming and Weight Loss

Attitudes towards feminism predict susceptibility to feminism‐related fake news

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

Seven newly identified loci for autoimmune thyroid disease

How has COVID-19 lockdown impacted smoking? A thematic analysis of written accounts from UK smokers

Haplotype tagging for the identification of common disease genes

CD226 Gly307Ser association with multiple autoimmune diseases

Duplex ultrasonography, magnetic resonance angiography, and computed tomography angiography for diagnosis and assessment of symptomatic, lower limb peripheral arterial disease: systematic review

Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2‑((4-(Benzo[d]thiazol-5-ylamino)-6‑(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases

Tumor Necrosis Factor-α-converting Enzyme (ADAM17) Mediates the Cleavage and Shedding of Fractalkine (CX3CL1)

Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS)

The predictors of and reasons for non-adherence in an observational cohort of patients with rheumatoid arthritis commencing methotrexate

Rates and predictors of methotrexate-related adverse events in patients with early rheumatoid arthritis: results from a nationwide UK study

Is the relationship between deprivation and outcomes in rheumatoid arthritis mediated by body mass index? A longitudinal cohort study

Nurse-led group consultation intervention reduces depressive symptoms in men with localised prostate cancer: a cluster randomised controlled trial

Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

The potential yield of active play in the prevention of cancer

Sepsis in Wales on the general wards: results of a feasibility pilot

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