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Ulipristal acetate - safety and pharmacokinetics following multiple doses of 10-50 mg per day

Journal of clinical pharmacy and therapeutics, 2013-08, Vol.38 (4), p.314-320

2013

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Inhibition of steroid sulfatase decreases endometriosis in an in vivo murine model

Human reproduction (Oxford), 2011-06, Vol.26 (6), p.1362-1370

2011

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Effects of erythromycin at steady-state concentrations on the pharmacokinetics of ulipristal acetate

Journal of clinical pharmacy and therapeutics, 2013-12, Vol.38 (6), p.512-517

2013

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AS601245, a c‐Jun NH2‐terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils

British journal of pharmacology, 2008-01, Vol.153 (1), p.157-163

2008

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AS601245, a c‐Jun NH 2 ‐terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils

British journal of pharmacology, 2009-01, Vol.153 (1), p.157-163

2009

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Design, Synthesis, and Biological Activity of Novel, Potent, and Selective (Benzoylaminomethyl)thiophene Sulfonamide Inhibitors of c-Jun-N-Terminal Kinase

Journal of medicinal chemistry, 2004-12, Vol.47 (27), p.6921-6934

2004

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O-135 Long term secondary efficacy of linzagolix for heavy menstrual bleeding (HMB) due to uterine fibroids (UF): 52-week results from two placebo-controlled, randomized, phase 3 trials

Human reproduction (Oxford), 2021-08, Vol.36 (Supplement_1)

2021

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Inhibition of Steroid Sulfatase Decreases Endometriosis in an In Vivo Murine Model

Obstetrical & gynecological survey, 2011-10, Vol.66 (10), p.620-622

2011

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Design and synthesis of new potential photoaffinity labels for mammalian squalene epoxidase

Bioorganic & medicinal chemistry letters, 1997-05, Vol.7 (9), p.1153-1156

1997

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Sulfonamide derivatives of benzylamine block cholesterol biosynthesis in HepG2 cells : A new type of potent squalene epoxidase inhibitors

Bioorganic & medicinal chemistry letters, 1998-06, Vol.8 (11), p.1337-1342

1998

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(Aryloxy)methylsilane Derivatives as New Cholesterol Biosynthesis Inhibitors: Synthesis and Hypocholesterolemic Activity of a New Class of Squalene Epoxidase Inhibitors

Journal of medicinal chemistry, 1995-08, Vol.38 (17), p.3207-3216

1995

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Design and synthesis of new hypocholesterolemic organosilanes with antioxidant properties

Bioorganic & medicinal chemistry letters, 1996-03, Vol.6 (5), p.533-538

1996

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Inhibition of c‐Jun N‐terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats

British journal of pharmacology, 2004-07, Vol.142 (6), p.953-960

2004

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Design and Synthesis of the First Generation of Novel Potent, Selective, and in Vivo Active (Benzothiazol-2-yl)acetonitrile Inhibitors of the c-Jun N-Terminal Kinase

Journal of medicinal chemistry, 2005-07, Vol.48 (14), p.4596-4607

2005

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AS601245 (1,3-benzothiazol-2-yl (2-[[2-(3-pyridinyl) ethyl] amino]-4 pyrimidinyl) acetonitrile): a c-Jun NH2-terminal protein kinase inhibitor with neuroprotective properties

The Journal of pharmacology and experimental therapeutics, 2004-07, Vol.310 (1), p.25

2004

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Control of death receptor and mitochondrial‐dependent apoptosis by c‐Jun N‐terminal kinase in hippocampal CA1 neurones following global transient ischaemia

Journal of neurochemistry, 2005-03, Vol.92 (5), p.1054-1060

2005

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Structure of dimethyl (±)-1,2,3,4,4aα,4b,9,10-octahydro-6,7-bis(trimethylsilyl)-2β,10aβ-ethanophenanthrene-12,12-dicarboxylate

Acta crystallographica. Section C, Crystal structure communications, 1990-07, Vol.46 (7), p.1271-1273

1990

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LINZAGOLIX FOR ENDOMETRIOSIS-ASSOCIATED PAIN: SAFETY RESULTS FROM EDELWEISS 3, A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

HUMAN REPRODUCTION, 2022, Vol.37, p.I111

2022

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Long term secondary efficacy of linzagolix for heavy menstrual bleeding (HMB) due to uterine fibroids (UF): 52-week results from two placebo-controlled, randomized, phase 3 trials

HUMAN REPRODUCTION, 2021, Vol.36, p.59

2021

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AS601245, a c-Jun NH sub(2)-terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils

British journal of pharmacology, 2008-01, Vol.153 (1), p.157-163

2008

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TRANSLATIONAL RESEARCH

Human reproduction (Oxford), 2012-07, Vol.27 (suppl_2), p.ii344-ii348

2012

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Stereoselective access to the basic skeleton of tetracyclic diterpenes via a sequence of consecutive [3 + 2], [2 + 2 + 2], and [4 + 2] cycloaddition reactions

Journal of organic chemistry, 1993-07, Vol.58 (16), p.4298-4305

1993

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Synthetic approach to aphidicolan and stemodan basic skeletons using a “Tandem Principle” [2+2+2] and [4+2] cycloaddition reactions

Tetrahedron letters, 1994-01, Vol.35 (3), p.417-420

1994

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A cellular assay for measuring the inhibition of glycogen synthase kinase-3 via the accumulation of beta-catenin in Chinese hamster ovary clone K1 cells

Assay and drug development technologies, 2006-08, Vol.4 (4), p.451-460

2006

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ChemInform Abstract: Design and Synthesis of New Potential Photoaffinity Labels for Mammalian Squalene Epoxidase

ChemInform, 1997-09, Vol.28 (40), p.no-no

1997

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Ulipristal acetate - safety and pharmacokinetics following multiple doses of 10-50 mg per day

Inhibition of steroid sulfatase decreases endometriosis in an in vivo murine model

Effects of erythromycin at steady-state concentrations on the pharmacokinetics of ulipristal acetate

AS601245, a c‐Jun NH2‐terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils

AS601245, a c‐Jun NH 2 ‐terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils

Design, Synthesis, and Biological Activity of Novel, Potent, and Selective (Benzoylaminomethyl)thiophene Sulfonamide Inhibitors of c-Jun-N-Terminal Kinase

O-135 Long term secondary efficacy of linzagolix for heavy menstrual bleeding (HMB) due to uterine fibroids (UF): 52-week results from two placebo-controlled, randomized, phase 3 trials

Inhibition of Steroid Sulfatase Decreases Endometriosis in an In Vivo Murine Model

Design and synthesis of new potential photoaffinity labels for mammalian squalene epoxidase

Sulfonamide derivatives of benzylamine block cholesterol biosynthesis in HepG2 cells : A new type of potent squalene epoxidase inhibitors

(Aryloxy)methylsilane Derivatives as New Cholesterol Biosynthesis Inhibitors: Synthesis and Hypocholesterolemic Activity of a New Class of Squalene Epoxidase Inhibitors

Design and synthesis of new hypocholesterolemic organosilanes with antioxidant properties

Inhibition of c‐Jun N‐terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats

Design and Synthesis of the First Generation of Novel Potent, Selective, and in Vivo Active (Benzothiazol-2-yl)acetonitrile Inhibitors of the c-Jun N-Terminal Kinase

AS601245 (1,3-benzothiazol-2-yl (2-[[2-(3-pyridinyl) ethyl] amino]-4 pyrimidinyl) acetonitrile): a c-Jun NH2-terminal protein kinase inhibitor with neuroprotective properties

Control of death receptor and mitochondrial‐dependent apoptosis by c‐Jun N‐terminal kinase in hippocampal CA1 neurones following global transient ischaemia

Structure of dimethyl (±)-1,2,3,4,4aα,4b,9,10-octahydro-6,7-bis(trimethylsilyl)-2β,10aβ-ethanophenanthrene-12,12-dicarboxylate

LINZAGOLIX FOR ENDOMETRIOSIS-ASSOCIATED PAIN: SAFETY RESULTS FROM EDELWEISS 3, A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

Long term secondary efficacy of linzagolix for heavy menstrual bleeding (HMB) due to uterine fibroids (UF): 52-week results from two placebo-controlled, randomized, phase 3 trials

AS601245, a c-Jun NH sub(2)-terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils

TRANSLATIONAL RESEARCH

Stereoselective access to the basic skeleton of tetracyclic diterpenes via a sequence of consecutive [3 + 2], [2 + 2 + 2], and [4 + 2] cycloaddition reactions

Synthetic approach to aphidicolan and stemodan basic skeletons using a “Tandem Principle” [2+2+2] and [4+2] cycloaddition reactions

A cellular assay for measuring the inhibition of glycogen synthase kinase-3 via the accumulation of beta-catenin in Chinese hamster ovary clone K1 cells

ChemInform Abstract: Design and Synthesis of New Potential Photoaffinity Labels for Mammalian Squalene Epoxidase

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