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Fine-Tuning Limited Proteolysis: A Major Role for Regulated Site-Specific O-Glycosylation

Trends in biochemical sciences (Amsterdam. Regular ed.), 2018-04, Vol.43 (4), p.269-284

2018

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A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation

Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (47), p.14623-14628

2015

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An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles

Nature communications, 2020-08, Vol.11 (1), p.4033-4033, Article 4033

2020

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“Glyco-sulfo barcodes” regulate chemokine receptor function

Cellular and molecular life sciences : CMLS, 2023-02, Vol.80 (2), p.55-55, Article 55

2023

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Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

The Journal of biological chemistry, 2018-05, Vol.293 (19), p.7408-7422

2018

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TAILS N-terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation

The Journal of biological chemistry, 2018-05, Vol.293 (20), p.7629-7644

2018

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Site-specific O-Glycosylation by Polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-transferase T2) Co-regulates β1-Adrenergic Receptor N-terminal Cleavage

The Journal of biological chemistry, 2017-03, Vol.292 (11), p.4714-4726

2017

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A Systematic Study of Site-specific GalNAc-type O-Glycosylation Modulating Proprotein Convertase Processing

The Journal of biological chemistry, 2011-11, Vol.286 (46), p.40122-40132

2011

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A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation

Glycobiology (Oxford), 2019-08, Vol.29 (9), p.645-656

2019

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Development of smart anti-glycan reagents using immunized lampreys

Communications biology, 2020-02, Vol.3 (1), p.91-91, Article 91

2020

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Novel lamprey antibody recognizes terminal sulfated galactose epitopes on mammalian glycoproteins

Communications biology, 2021-06, Vol.4 (1), p.674-674, Article 674

2021

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Emerging patterns of tyrosine sulfation and O-glycosylation cross-talk and co-localization

Current opinion in structural biology, 2020-06, Vol.62, p.102-111

2020

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Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor

The Journal of biological chemistry, 2019-08, Vol.294 (34), p.12567-12578

2019

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Deconstruction of O-glycosylation-GalNAc-T isoforms direct distinct subsets of the O-glycoproteome

EMBO reports, 2015-12, Vol.16 (12), p.1713-1722

2015

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Altered O-glycosylation of β1-adrenergic receptor N-terminal single-nucleotide variants modulates receptor processing and functional activity

The FEBS journal, 2024-08

2024

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Altered O-glycosylation of β 1 -adrenergic receptor N-terminal single-nucleotide variants modulates receptor processing and functional activity

The FEBS journal, 2024-08

2024

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Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines

The Journal of biological chemistry, 2018-12, Vol.293 (49), p.19064-19077

2018

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G Protein-Coupled Receptors in the Sweet Spot: Glycosylation and other Post-translational Modifications

ACS pharmacology & translational science, 2020-04, Vol.3 (2), p.237-245

2020

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Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation

Cell chemical biology, 2023-08, Vol.30 (8), p.893-905.e7

2023

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Site-specific O-glycosylation of N-terminal serine residues by polypeptide GalNAc-transferase 2 modulates human δ-opioid receptor turnover at the plasma membrane

Cellular signalling, 2018-01, Vol.42, p.184-193

2018

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Glycocalyx shedding patterns identifies antipsychotic-naïve patients with first-episode psychosis

Psychiatry research, 2024-09, Vol.339, p.116037, Article 116037

2024

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Parallel Glyco-SPOT Synthesis of Glycopeptide Libraries

Cell chemical biology, 2020-09, Vol.27 (9), p.1207-1219.e9

2020

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Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

The Journal of biological chemistry, 2019-05, Vol.294 (21), p.8349-8349

2019

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Correction: Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor

The Journal of biological chemistry, 2019-11, Vol.294 (48), p.18516-18516

2019

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Abstract 14933: Beta1-Adrenergic Receptor Polymorphisms Modulate Receptor Processing and Function

Circulation (New York, N.Y.), 2022-11, Vol.146 (Suppl_1)

2022

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Fine-Tuning Limited Proteolysis: A Major Role for Regulated Site-Specific O-Glycosylation

A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation

An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles

“Glyco-sulfo barcodes” regulate chemokine receptor function

Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

TAILS N-terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation

Site-specific O-Glycosylation by Polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-transferase T2) Co-regulates β1-Adrenergic Receptor N-terminal Cleavage

A Systematic Study of Site-specific GalNAc-type O-Glycosylation Modulating Proprotein Convertase Processing

A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation

Development of smart anti-glycan reagents using immunized lampreys

Novel lamprey antibody recognizes terminal sulfated galactose epitopes on mammalian glycoproteins

Emerging patterns of tyrosine sulfation and O-glycosylation cross-talk and co-localization

Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor

Deconstruction of O-glycosylation-GalNAc-T isoforms direct distinct subsets of the O-glycoproteome

Altered O-glycosylation of β1-adrenergic receptor N-terminal single-nucleotide variants modulates receptor processing and functional activity

Altered O-glycosylation of β 1 -adrenergic receptor N-terminal single-nucleotide variants modulates receptor processing and functional activity

Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines

G Protein-Coupled Receptors in the Sweet Spot: Glycosylation and other Post-translational Modifications

Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation

Site-specific O-glycosylation of N-terminal serine residues by polypeptide GalNAc-transferase 2 modulates human δ-opioid receptor turnover at the plasma membrane

Glycocalyx shedding patterns identifies antipsychotic-naïve patients with first-episode psychosis

Parallel Glyco-SPOT Synthesis of Glycopeptide Libraries

Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

Correction: Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor

Abstract 14933: Beta1-Adrenergic Receptor Polymorphisms Modulate Receptor Processing and Function

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