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Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

The Journal of experimental medicine, 2017-08, Vol.214 (8), p.2243-2255

2017

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ICOS is upregulated on T cells following radiation and agonism combined with radiation results in enhanced tumor control

Scientific reports, 2022-09, Vol.12 (1), p.14954-14954, Article 14954

2022

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Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching

Nature (London), 2015-09, Vol.525 (7567), p.134-139

2015

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MDC1 Maintains Genomic Stability by Participating in the Amplification of ATM-Dependent DNA Damage Signals

Molecular cell, 2006-01, Vol.21 (2), p.187-200

2006

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ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models

PloS one, 2020-09, Vol.15 (9), p.e0239595-e0239595

2020

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Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

Genes & development, 2008-06, Vol.22 (12), p.1662-1676

2008

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Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (7), p.2473-2478

2012

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Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.10269-10274

2014

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The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

Nature (London), 2002-10, Vol.419 (6909), p.853-857

2002

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H2AX Prevents DNA Breaks from Progressing to Chromosome Breaks and Translocations

Molecular cell, 2006-01, Vol.21 (2), p.201-214

2006

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Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis

Nature cell biology, 2002-01, Vol.4 (1), p.11-19

2002

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Mechanisms promoting translocations in editing and switching peripheral B cells

Nature (London), 2009-07, Vol.460 (7252), p.231-236

2009

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Direct p53 Transcriptional Repression: In Vivo Analysis of CCAAT-Containing G2/M Promoters

Molecular and Cellular Biology, 2005-05, Vol.25 (9), p.3737-3751

2005

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The Role of Mechanistic Factors in Promoting Chromosomal Translocations Found in Lymphoid and Other Cancers

Advances in Immunology, 2010-01, Vol.106, p.93-133

2010

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IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.2644-2649

2014

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Pin1 Links the Activities of c-Abl and p300 in Regulating p73 Function

Molecular cell, 2004-06, Vol.14 (5), p.625-636

2004

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Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1

The EMBO journal, 1999-11, Vol.18 (22), p.6462-6471

1999

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Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (8), p.2934-2939

2013

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Transcriptional Activation of the Cyclin A Gene by the Architectural Transcription Factor HMGA2

Molecular and Cellular Biology, 2003-12, Vol.23 (24), p.9104-9116

2003

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Chromosomal location targets different MYC family gene members for oncogenic translocations

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (7), p.2265-2270

2009

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217 Evaluating biomarkers of JTX-8064 (anti-LILRB2/ILT4 monoclonal antibody) in an ex vivo human tumor histoculture system to inform clinical development

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A129-A130

2020

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The Transcriptional Repressor hDaxx Potentiates p53-dependent Apoptosis

The Journal of biological chemistry, 2004-11, Vol.279 (46), p.48013-48023

2004

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Modification of the Erythroid Transcription Factor GATA-1 by SUMO-1

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (24), p.8870-8875

2004

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Mechanisms that promote and suppress chromosomal translocations in lymphocytes

Annual review of immunology, 2011-04, Vol.29 (1), p.319-350

2011

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Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

ICOS is upregulated on T cells following radiation and agonism combined with radiation results in enhanced tumor control

Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching

MDC1 Maintains Genomic Stability by Participating in the Amplification of ATM-Dependent DNA Damage Signals

ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)

Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes

Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

H2AX Prevents DNA Breaks from Progressing to Chromosome Breaks and Translocations

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis

Mechanisms promoting translocations in editing and switching peripheral B cells

Direct p53 Transcriptional Repression: In Vivo Analysis of CCAAT-Containing G2/M Promoters

The Role of Mechanistic Factors in Promoting Chromosomal Translocations Found in Lymphoid and Other Cancers

IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances

Pin1 Links the Activities of c-Abl and p300 in Regulating p73 Function

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1

Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas

Transcriptional Activation of the Cyclin A Gene by the Architectural Transcription Factor HMGA2

Chromosomal location targets different MYC family gene members for oncogenic translocations

217 Evaluating biomarkers of JTX-8064 (anti-LILRB2/ILT4 monoclonal antibody) in an ex vivo human tumor histoculture system to inform clinical development

The Transcriptional Repressor hDaxx Potentiates p53-dependent Apoptosis

Modification of the Erythroid Transcription Factor GATA-1 by SUMO-1

Mechanisms that promote and suppress chromosomal translocations in lymphocytes

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