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Allosteric modulation of nicotinic acetylcholine receptors

Biochemical pharmacology, 2007-10, Vol.74 (8), p.1155-1163

2007

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Distinct Profiles of α7 nAChR Positive Allosteric Modulation Revealed by Structurally Diverse Chemotypes

Molecular pharmacology, 2007-09, Vol.72 (3), p.715-724

2007

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Short-term oral gavage administration of adenine induces a model of fibrotic kidney disease in rats

Journal of pharmacological and toxicological methods, 2018-11, Vol.94 (Pt 1), p.34-43

2018

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Potassium channels: molecular defects, diseases, and therapeutic opportunities

Pharmacological reviews, 2000-12, Vol.52 (4), p.557

2000

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α7 nAChR-mediated activation of MAP kinase pathways in PC12 cells

Brain research, 2010-04, Vol.1328, p.1-11

2010

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Securitization of refugees in South Asia: Through the prism of Kautilya’s Arthashastra

Asian journal of comparative politics, 2020-12, Vol.5 (4), p.400-415

Gopalakrishnan, Murali

2020

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Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor

Journal of medicinal chemistry, 2009-05, Vol.52 (10), p.3377-3384

2009

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High content screen microscopy analysis of Aβ1–42 -induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands

Brain research, 2007-09, Vol.1151, p.227-235

2007

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Recent Developments in the Biology and Medicinal Chemistry of Potassium Channel Modulators: Update from a Decade of Progress

Journal of medicinal chemistry, 2001-05, Vol.44 (11), p.1627-1653

2001

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SAR of α7 nicotinic receptor agonists derived from tilorone: Exploration of a novel nicotinic pharmacophore

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (4), p.1633-1638

2012

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On Becoming a Pharmacologist: Channeling David Triggle

Biochemical pharmacology, 2015-11, Vol.98 (2), p.292-298

2015

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Voltage-Gated Ion Channels as Drug Targets

1. Aufl., 2006

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Antisense knockdown of the rat α7 nicotinic acetylcholine receptor produces spatial memory impairment

Neuroscience letters, 2006-12, Vol.410 (1), p.15-19

2006

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Spontaneous phasic activity of the pig urinary bladder smooth muscle: characteristics and sensitivity to potassium channel modulators

British journal of pharmacology, 2002-02, Vol.135 (3), p.639-648

2002

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Human α4β2 Neuronal Nicotinic Acetylcholine Receptor in HEK 293 Cells: A Patch-Clamp Study

The Journal of neuroscience, 1996-12, Vol.16 (24), p.7880-7891

1996

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Characterization of human ASIC2a homomeric channels stably expressed in murine Ltk − cells

Life sciences (1973), 2008-01, Vol.82 (1), p.30-40

2008

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Differential action potentials and firing patterns in injured and uninjured small dorsal root ganglion neurons after nerve injury

Brain research, 2004-05, Vol.1009 (1), p.147-158

2004

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A Festschrift in honor of David J. Triggle

Biochemical pharmacology, 2015-11, Vol.98 (2), p.267-268

2015

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Utility of large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonists

Journal of biomolecular screening, 2007-02, Vol.12 (1), p.61-69

2007

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Effects of Substitution on 9-(3-Bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4- azacyclopenta[b]naphthalene-1,8-dione, a Dihydropyridine ATP-Sensitive Potassium Channel Opener

Journal of medicinal chemistry, 2006-11, Vol.49 (23), p.6869-6887

2006

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Functional characterization of large conductance calcium-activated K+ channel openers in bladder and vascular smooth muscle

Naunyn-Schmiedeberg's archives of pharmacology, 2004-05, Vol.369 (5), p.481-489

2004

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Annular swirling jet reactor for converting hydrocarbons to olefins and aromatics

Chemical engineering journal (Lausanne, Switzerland : 1996), 2024-01, Vol.479, p.147827, Article 147827

2024

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Distinct Profiles of alpha 7 nAChR Positive Allosteric Modulation Revealed by Structurally Diverse Chemotypes

Molecular pharmacology, 2007-09, Vol.72 (3), p.715-724

2007

Volltextzugriff (PDF)

Positive allosteric modulation of α7 neuronal nicotinic acetylcholine receptors: lack of cytotoxicity in PC12 cells and rat primary cortical neurons

British journal of pharmacology, 2009-12, Vol.158 (8), p.1857-1864

2009

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Association of Catsper1 or -2 with Cav3.3 Leads to Suppression of T-type Calcium Channel Activity

The Journal of biological chemistry, 2006-08, Vol.281 (31), p.22332-22341

2006

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Allosteric modulation of nicotinic acetylcholine receptors

Distinct Profiles of α7 nAChR Positive Allosteric Modulation Revealed by Structurally Diverse Chemotypes

Short-term oral gavage administration of adenine induces a model of fibrotic kidney disease in rats

Potassium channels: molecular defects, diseases, and therapeutic opportunities

α7 nAChR-mediated activation of MAP kinase pathways in PC12 cells

Securitization of refugees in South Asia: Through the prism of Kautilya’s Arthashastra

Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor

High content screen microscopy analysis of Aβ1–42 -induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands

Recent Developments in the Biology and Medicinal Chemistry of Potassium Channel Modulators: Update from a Decade of Progress

SAR of α7 nicotinic receptor agonists derived from tilorone: Exploration of a novel nicotinic pharmacophore

On Becoming a Pharmacologist: Channeling David Triggle

Voltage-Gated Ion Channels as Drug Targets

Antisense knockdown of the rat α7 nicotinic acetylcholine receptor produces spatial memory impairment

Spontaneous phasic activity of the pig urinary bladder smooth muscle: characteristics and sensitivity to potassium channel modulators

Human α4β2 Neuronal Nicotinic Acetylcholine Receptor in HEK 293 Cells: A Patch-Clamp Study

Characterization of human ASIC2a homomeric channels stably expressed in murine Ltk − cells

Differential action potentials and firing patterns in injured and uninjured small dorsal root ganglion neurons after nerve injury

A Festschrift in honor of David J. Triggle

Utility of large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonists

Effects of Substitution on 9-(3-Bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4- azacyclopenta[b]naphthalene-1,8-dione, a Dihydropyridine ATP-Sensitive Potassium Channel Opener

Functional characterization of large conductance calcium-activated K+ channel openers in bladder and vascular smooth muscle

Annular swirling jet reactor for converting hydrocarbons to olefins and aromatics

Distinct Profiles of alpha 7 nAChR Positive Allosteric Modulation Revealed by Structurally Diverse Chemotypes

Positive allosteric modulation of α7 neuronal nicotinic acetylcholine receptors: lack of cytotoxicity in PC12 cells and rat primary cortical neurons

Association of Catsper1 or -2 with Cav3.3 Leads to Suppression of T-type Calcium Channel Activity

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