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Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents

Clinical cancer research, 2013-02, Vol.19 (3), p.657-667

2013

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Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications

Pigment cell and melanoma research, 2018-01, Vol.31 (1), p.11-30

2018

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Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in Braf-Mutant Human Cutaneous Melanoma Cells

Cancer research (Chicago, Ill.), 2010-11, Vol.70 (21), p.8736-8747

2010

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Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target

Clinical cancer research, 2014-11, Vol.20 (21), p.5537-5546

2014

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A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma

Clinical cancer research, 2019-11, Vol.25 (21), p.6429-6442

2019

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Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [ 18 F]FAZA PET In Vivo

Cells (Basel, Switzerland), 2019-11, Vol.8 (12), p.1487

2019

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Tumour-intrinsic endomembrane trafficking by ARF6 shapes an immunosuppressive microenvironment that drives melanomagenesis and response to checkpoint blockade therapy

Nature communications, 2024-08, Vol.15 (1), p.6613-18, Article 6613

2024

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ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma

Cancer research (Chicago, Ill.), 2017-11, Vol.77 (21), p.5873-5885

2017

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Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition

Pigment cell and melanoma research, 2012-03, Vol.25 (2), p.248-258

2012

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Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas

Cancer & metabolism, 2022-02, Vol.10 (1), p.6-18, Article 6

2022

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Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

Cancer cell, 2017-02, Vol.31 (2), p.225-239

2017

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The Glutaminase Inhibitor CB-839 (Telaglenastat) Enhances the Antimelanoma Activity of T-Cell-Mediated Immunotherapies

Molecular cancer therapeutics, 2021-03, Vol.20 (3), p.500-511

2021

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Clinical, molecular, metabolic, and immune features associated with oxidative phosphorylation in melanoma brain metastases

Neuro-oncology advances, 2021-01, Vol.3 (1), p.vdaa177-vdaa177

2021

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Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma

Cancer research (Chicago, Ill.), 2014-12, Vol.74 (23), p.7037-7047

2014

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Consequences of early postnatal lipopolysaccharide exposure on developing lungs in mice

American journal of physiology. Lung cellular and molecular physiology, 2019-01, Vol.316 (1), p.L229-L244

2019

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Lung omics signatures in a bronchopulmonary dysplasia and pulmonary hypertension-like murine model

American journal of physiology. Lung cellular and molecular physiology, 2018-11, Vol.315 (5), p.L734-L741

2018

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Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates

Molecular cancer therapeutics, 2009-08, Vol.8 (8), p.2079-2085

2009

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Combinatorial Determination of Sequence Specificity for Nanomolar DNA-Binding Hairpin Polyamides

Biochemistry (Easton), 2003-06, Vol.42 (22), p.6891-6903

2003

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Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions

Molecular cancer therapeutics, 2009-03, Vol.8 (3), p.552-562

2009

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Depletion of histone deacetylase protein: a common consequence of inflammatory cytokine signaling?

Cell cycle (Georgetown, Tex.), 2006-12, Vol.5 (23), p.2738-2743

2006

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Tumour necrosis factor-α depletes histone deacetylase 1 protein through IKK2

EMBO reports, 2006-03, Vol.7 (3), p.291-296

2006

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Constitutive and inducible nuclear factor-κB in immortalized normal human bronchial epithelial and non-small cell lung cancer cell lines

Cancer letters, 2007-09, Vol.255 (1), p.85-94

2007

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Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma

Clinical cancer research, 2023-01, Vol.29 (1), p.154-164

2023

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Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications

Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in Braf-Mutant Human Cutaneous Melanoma Cells

Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target

A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma

Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [ 18 F]FAZA PET In Vivo

Tumour-intrinsic endomembrane trafficking by ARF6 shapes an immunosuppressive microenvironment that drives melanomagenesis and response to checkpoint blockade therapy

ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma

Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition

Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas

Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

The Glutaminase Inhibitor CB-839 (Telaglenastat) Enhances the Antimelanoma Activity of T-Cell-Mediated Immunotherapies

Clinical, molecular, metabolic, and immune features associated with oxidative phosphorylation in melanoma brain metastases

Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma

Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

Consequences of early postnatal lipopolysaccharide exposure on developing lungs in mice

Lung omics signatures in a bronchopulmonary dysplasia and pulmonary hypertension-like murine model

Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates

Combinatorial Determination of Sequence Specificity for Nanomolar DNA-Binding Hairpin Polyamides

Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions

Depletion of histone deacetylase protein: a common consequence of inflammatory cytokine signaling?

Tumour necrosis factor-α depletes histone deacetylase 1 protein through IKK2

Constitutive and inducible nuclear factor-κB in immortalized normal human bronchial epithelial and non-small cell lung cancer cell lines

Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma

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