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Multistep pathogenesis of autoimmune disease

Cell, 2007-07, Vol.130 (1), p.25-35

Goodnow, Christopher C

2007

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Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization

The Journal of experimental medicine, 2016-06, Vol.213 (7), p.1255-1265

2016

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High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

Nature communications, 2019-07, Vol.10 (1), p.3120-13, Article 3120

2019

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Multistep Pathogenesis of Autoimmune Disease

Cell, 2007-07, Vol.130 (1), p.25-35

Goodnow, Christopher C.

2007

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HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse

PLoS genetics, 2015-10, Vol.11 (10), p.e1005620-e1005620

2015

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Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity

Immunological reviews, 2019-11, Vol.292 (1), p.61-75

2019

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Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination

Science (American Association for the Advancement of Science), 2018-04, Vol.360 (6385), p.223-226

2018

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Comparison of predicted and actual consequences of missense mutations

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (37), p.E5189-E5198

2015

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Cellular and genetic mechanisms of self tolerance and autoimmunity

Nature, 2005-06, Vol.435 (7042), p.590-597

2005

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Aire regulates negative selection of organ-specific T cells

Nature immunology, 2003-04, Vol.4 (4), p.350-354

2003

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Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate

Nucleic acids research, 2021-11, Vol.49 (19), p.e109-e109

2021

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Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (25), p.E2567-E2575

2014

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Reliably Detecting Clinically Important Variants Requires Both Combined Variant Calls and Optimized Filtering Strategies

PloS one, 2015-11, Vol.10 (11), p.e0143199

2015

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Roquin-2 Shares Functions with Its Paralog Roquin-1 in the Repression of mRNAs Controlling T Follicular Helper Cells and Systemic Inflammation

Immunity (Cambridge, Mass.), 2013-04, Vol.38 (4), p.669-680

2013

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Two levels of protection for the B cell genome during somatic hypermutation

Nature, 2008-02, Vol.451 (7180), p.841-845

2008

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LRGUK-1 is required for basal body and manchette function during spermatogenesis and male fertility

PLoS genetics, 2015-03, Vol.11 (3), p.e1005090-e1005090

2015

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Balancing Immunity and Tolerance: Deleting and Tuning Lymphocyte Repertoires

Proceedings of the National Academy of Sciences - PNAS, 1996-03, Vol.93 (6), p.2264-2271

Goodnow, Christopher C.

1996

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Differential activation of transcription factors induced by Ca2+ response amplitude and duration

Nature (London), 1997-04, Vol.386 (6627), p.855-858

1997

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Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

PLoS medicine, 2008-03, Vol.5 (3), p.e54-e54

2008

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SAMD9L autoinflammatory or ataxia pancytopenia disease mutations activate cell-autonomous translational repression

Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (34), p.1-11

2021

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DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns

Cancer cell, 2019-02, Vol.35 (2), p.297-314.e8

2019

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IgD attenuates the IgM-induced anergy response in transitional and mature B cells

Nature communications, 2016-11, Vol.7 (1), p.13381-13381, Article 13381

2016

Volltextzugriff (PDF)

Loss-of-function of Fbxo10, encoding a post-translational regulator of BCL2 in lymphomas, has no discernible effect on BCL2 or B lymphocyte accumulation in mice

PloS one, 2021-04, Vol.16 (4), p.e0237830-e0237830

2021

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An essential role for katanin p80 and microtubule severing in male gamete production

PLoS genetics, 2012-05, Vol.8 (5), p.e1002698-e1002698

2012

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Multistep pathogenesis of autoimmune disease

Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization

High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

Multistep Pathogenesis of Autoimmune Disease

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse

Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity

Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination

Comparison of predicted and actual consequences of missense mutations

Cellular and genetic mechanisms of self tolerance and autoimmunity

Aire regulates negative selection of organ-specific T cells

Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate

Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity

Reliably Detecting Clinically Important Variants Requires Both Combined Variant Calls and Optimized Filtering Strategies

Roquin-2 Shares Functions with Its Paralog Roquin-1 in the Repression of mRNAs Controlling T Follicular Helper Cells and Systemic Inflammation

Two levels of protection for the B cell genome during somatic hypermutation

LRGUK-1 is required for basal body and manchette function during spermatogenesis and male fertility

Balancing Immunity and Tolerance: Deleting and Tuning Lymphocyte Repertoires

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

SAMD9L autoinflammatory or ataxia pancytopenia disease mutations activate cell-autonomous translational repression

Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes

DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns

IgD attenuates the IgM-induced anergy response in transitional and mature B cells

Loss-of-function of Fbxo10, encoding a post-translational regulator of BCL2 in lymphomas, has no discernible effect on BCL2 or B lymphocyte accumulation in mice

An essential role for katanin p80 and microtubule severing in male gamete production

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