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Urokinase receptor primes cells to proliferate in response to epidermal growth factor

Oncogene, 2007-04, Vol.26 (18), p.2585-2594

2007

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Endogenously produced urokinase-type plasminogen activator is a major determinant of the basal level of activated ERK/MAP kinase and prevents apoptosis in MDA-MB-231 breast cancer cells

Journal of cell science, 2001-09, Vol.114 (Pt 18), p.3387-3396

2001

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Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling

Oncogene, 2015-07, Vol.34 (31), p.4078-4088

2015

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Platelet activation during coronary angioplasty in humans

Circulation (New York, N.Y.), 1993-12, Vol.88 (6), p.2728-2734

1993

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Myosin Light Chain Kinase Functions Downstream of Ras/ERK to Promote Migration of Urokinase-Type Plasminogen Activator-Stimulated Cells in an Integrin-Selective Manner

The Journal of cell biology, 1999-07, Vol.146 (1), p.149-164

1999

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Plasmin cleaves betaglycan and releases a 60 kDa transforming growth factor-β complex from the cell surface

Biochemical journal, 1994-08, Vol.302 (1), p.199-205

1994

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Characterization and immunohistochemical localization of alpha 2- macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain

The American journal of pathology, 1992-07, Vol.141 (1), p.37-42

1992

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Inhibition of cell surface receptor-bound plasmin by alpha 2-antiplasmin and alpha 2-macroglobulin

The Journal of biological chemistry, 1991-07, Vol.266 (19), p.12329-12336

1991

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Binding of Urokinase-type Plasminogen Activator to Its Receptor in MCF-7 Cells Activates Extracellular Signal-regulated Kinase 1 and 2 Which Is Required for Increased Cellular Motility

The Journal of biological chemistry, 1998-04, Vol.273 (14), p.8502-8507

1998

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Proteolytic activation of single-chain precursor macrophage-stimulating protein by nerve growth factor-gamma and epidermal growth factor-binding protein, members of the kallikrein family

The Journal of biological chemistry, 1994-05, Vol.269 (19), p.13806-13810

1994

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Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion

Journal of cell science, 2000-01, Vol.113 ( Pt 1) (1), p.123-134

2000

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Plasminogen Activator Inhibitor 1 Functions as a Urokinase Response Modifier at the Level of Cell Signaling and Thereby Promotes MCF-7 Cell Growth

The Journal of cell biology, 2001-02, Vol.152 (4), p.741-751

2001

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Nerve growth factor-gamma activates soluble and receptor-bound single chain urokinase-type plasminogen activator

The Journal of biological chemistry, 1993-08, Vol.268 (22), p.16327-16331

1993

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Urokinase-type Plasminogen Activator Stimulates the Ras/Extracellular Signal-regulated Kinase (ERK) Signaling Pathway and MCF-7 Cell Migration by a Mechanism That Requires Focal Adhesion Kinase, Src, and Shc. Rapid dissociation of GRB2/SOS-SHC complex is associated with the transient phosphorylation of ERK in urokinase-treated cells

The Journal of biological chemistry, 2000-06, Vol.275 (25), p.19382-19388

2000

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Effects of bacterial lipopolysaccharide on the hydrolysis of phosphatidylinositol-4,5-bisphosphate in murine peritoneal macrophages

The Journal of immunology (1950), 1987-07, Vol.139 (2), p.526-533

1987

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LDL receptor family-dependent and -independent pathways for the internalization and digestion of lipoprotein lipase-associated beta-VLDL by rat vascular smooth muscle cells

Journal of lipid research, 1997-09, Vol.38 (9), p.1841-1850

1997

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Epidermal growth factor differentially regulates low density lipoprotein receptor-related protein gene expression in neoplastic and fetal human astrocytes

Glia, 1999-01, Vol.25 (1), p.71-84

1999

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The Very Low Density Lipoprotein Receptor Regulates Urokinase Receptor Catabolism and Breast Cancer Cell Motility in Vitro

The Journal of biological chemistry, 1999-03, Vol.274 (11), p.7412-7420

1999

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Plasminogen activator inhibitor-1 in the cerebrospinal fluid as an index of neurological disease

Blood coagulation & fibrinolysis, 1994-04, Vol.5 (2), p.167-172

1994

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Activated alpha 2-macroglobulin and transforming growth factor-beta 1 induce a synergistic smooth muscle cell proliferative response

The Journal of biological chemistry, 1993-08, Vol.268 (24), p.18340-18344

1993

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Proteolytically active streptococcal pyrogenic exotoxin B cleaves monocytic cell urokinase receptor and releases an active fragment of the receptor from the cell surface

The Journal of biological chemistry, 1994-12, Vol.269 (48), p.30682-30687

1994

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Model of alpha 2-macroglobulin structure and function

Proceedings of the National Academy of Sciences - PNAS, 1985-09, Vol.82 (17), p.5700-5704

1985

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Soluble fibrin preparations inhibit the reaction of plasmin with α2-macroglobulin : comparison with α2-antiplasmin and leupeptin

Biochemical journal, 1991-04, Vol.275 (1), p.53-59

1991

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Plasmin modulates the thrombin-evoked calcium response in C6 glioma cells

Biochemical journal, 1994, Vol.297 (1), p.175-179

1994

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alpha.-Macroglobulin from Limulus polyphemus exhibits proteinase inhibitory activity and participates in a hemolytic system

Biochemistry (Easton), 1990-10, Vol.29 (43), p.10070-10080

1990

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Urokinase receptor primes cells to proliferate in response to epidermal growth factor

Endogenously produced urokinase-type plasminogen activator is a major determinant of the basal level of activated ERK/MAP kinase and prevents apoptosis in MDA-MB-231 breast cancer cells

Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling

Platelet activation during coronary angioplasty in humans

Myosin Light Chain Kinase Functions Downstream of Ras/ERK to Promote Migration of Urokinase-Type Plasminogen Activator-Stimulated Cells in an Integrin-Selective Manner

Plasmin cleaves betaglycan and releases a 60 kDa transforming growth factor-β complex from the cell surface

Characterization and immunohistochemical localization of alpha 2- macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain

Inhibition of cell surface receptor-bound plasmin by alpha 2-antiplasmin and alpha 2-macroglobulin

Binding of Urokinase-type Plasminogen Activator to Its Receptor in MCF-7 Cells Activates Extracellular Signal-regulated Kinase 1 and 2 Which Is Required for Increased Cellular Motility

Proteolytic activation of single-chain precursor macrophage-stimulating protein by nerve growth factor-gamma and epidermal growth factor-binding protein, members of the kallikrein family

Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion

Plasminogen Activator Inhibitor 1 Functions as a Urokinase Response Modifier at the Level of Cell Signaling and Thereby Promotes MCF-7 Cell Growth

Nerve growth factor-gamma activates soluble and receptor-bound single chain urokinase-type plasminogen activator

Effects of bacterial lipopolysaccharide on the hydrolysis of phosphatidylinositol-4,5-bisphosphate in murine peritoneal macrophages

LDL receptor family-dependent and -independent pathways for the internalization and digestion of lipoprotein lipase-associated beta-VLDL by rat vascular smooth muscle cells

Epidermal growth factor differentially regulates low density lipoprotein receptor-related protein gene expression in neoplastic and fetal human astrocytes

The Very Low Density Lipoprotein Receptor Regulates Urokinase Receptor Catabolism and Breast Cancer Cell Motility in Vitro

Plasminogen activator inhibitor-1 in the cerebrospinal fluid as an index of neurological disease

Activated alpha 2-macroglobulin and transforming growth factor-beta 1 induce a synergistic smooth muscle cell proliferative response

Proteolytically active streptococcal pyrogenic exotoxin B cleaves monocytic cell urokinase receptor and releases an active fragment of the receptor from the cell surface

Model of alpha 2-macroglobulin structure and function

Soluble fibrin preparations inhibit the reaction of plasmin with α2-macroglobulin : comparison with α2-antiplasmin and leupeptin

Plasmin modulates the thrombin-evoked calcium response in C6 glioma cells

alpha.-Macroglobulin from Limulus polyphemus exhibits proteinase inhibitory activity and participates in a hemolytic system

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