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Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

Journal of medicinal chemistry, 2009-01, Vol.52 (2), p.514-523

2009

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Design and synthesis of pyridine–pyrazolopyridine-based inhibitors of protein kinase B/Akt

Bioorganic & medicinal chemistry, 2007-03, Vol.15 (6), p.2441-2452

2007

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Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancer

Bioorganic & medicinal chemistry, 2012-08, Vol.20 (15), p.4635-4645

2012

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Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension

Journal of medicinal chemistry, 2007-06, Vol.50 (13), p.2990-3003

2007

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Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituent

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.3955-3958

2008

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Discovery and SAR of oxindole–pyridine-based protein kinase B/Akt inhibitors for treating cancers

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (13), p.3424-3429

2006

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Design of Infrared Imaging System in Front of Vehicle

Journal of physics. Conference series, 2020-10, Vol.1624 (5), p.52006

2020

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Isoquinoline–pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (12), p.3150-3155

2006

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Infrared Imaging Principle of the Front of the Vehicle

Journal of physics. Conference series, 2020-10, Vol.1624 (5), p.52007

2020

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Synthesis and structure–activity relationship of 3,4′-bispyridinylethylenes: Discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (7), p.2000-2007

2006

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Discovery of trans-3,4′-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (6), p.1679-1685

2006

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Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer

Bioorganic & medicinal chemistry, 2008-07, Vol.16 (14), p.6965-6975

2008

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A Stochastic Resonance Phenomenon in Linear Models

Applied Mechanics and Materials, 2013-09, Vol.401-403, p.1301-1304

2013

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Stochastic Resonance in FitzHugh-Nagumo Neural Model

Applied Mechanics and Materials, 2013-09, Vol.415 (Automatic Control and Mechatronic Engineering II), p.298-302

2013

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A Method on Realizing Signal Generator for Arbitrary Waveform

Applied Mechanics and Materials, 2013-07, Vol.333-335, p.661-665

2013

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Signal Generator Design Based on the FPGA

Applied Mechanics and Materials, 2013-07, Vol.333-335, p.2407-2411

2013

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Based on the FTA of Electronic-Control Engine Start Fault Diagnosis Analysis

Applied Mechanics and Materials, 2013-02, Vol.303-306, p.871-875

2013

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Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[( R )-2-methylpyrrolidin-2-yl]-1 H -benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

Journal of medicinal chemistry, 2009-01, Vol.52 (2), p.514-523

2009

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Alkynylatlon of aldehydic CH bonds via reaction with acetylenic triflones

Tetrahedron letters, 1997-02, Vol.38 (5), p.787-790

1997

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Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1 H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer

Bioorganic & medicinal chemistry, 2008, Vol.16 (14), p.6965-6975

2008

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Discovery and SAR of 2-(l-propylpiperidin-4-yl)-lH-benzimidazole-4-carboxamide : A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer

Bioorganic & medicinal chemistry, 2008, Vol.16 (14), p.6965-6975

2008

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Alkynylation of C−H Bonds via Reaction with Acetylenic Triflones 1

Journal of the American Chemical Society, 1996-01, Vol.118 (18), p.4486-4487

1996

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Stereospecific Alkenylation of C−H Bonds via Reaction with β-Heteroatom-Functionalized Trisubstituted Vinyl Triflones 1

Journal of the American Chemical Society, 1997-05, Vol.119 (18), p.4123-4129

1997

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Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

Design and synthesis of pyridine–pyrazolopyridine-based inhibitors of protein kinase B/Akt

Discovery and SAR of orally efficacious tetrahydropyridopyridazinone PARP inhibitors for the treatment of cancer

Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension

Synthesis and SAR of novel, potent and orally bioavailable benzimidazole inhibitors of poly(ADP-ribose) polymerase (PARP) with a quaternary methylene-amino substituent

Discovery and SAR of oxindole–pyridine-based protein kinase B/Akt inhibitors for treating cancers

Design of Infrared Imaging System in Front of Vehicle

Isoquinoline–pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity

Infrared Imaging Principle of the Front of the Vehicle

Synthesis and structure–activity relationship of 3,4′-bispyridinylethylenes: Discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer

Discovery of trans-3,4′-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation

Optimization of Phenyl-Substituted Benzimidazole Carboxamide Poly(ADP-Ribose) Polymerase Inhibitors: Identification of ( S )-2-(2-Fluoro-4-(pyrrolidin-2-yl)phenyl)-1 H -benzimidazole-4-carboxamide (A-966492), a Highly Potent and Efficacious Inhibitor

Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer

A Stochastic Resonance Phenomenon in Linear Models

Stochastic Resonance in FitzHugh-Nagumo Neural Model

A Method on Realizing Signal Generator for Arbitrary Waveform

Signal Generator Design Based on the FPGA

Based on the FTA of Electronic-Control Engine Start Fault Diagnosis Analysis

Optimization of Phenyl-Substituted Benzimidazole Carboxamide Poly(ADP-Ribose) Polymerase Inhibitors: Identification of (S)-2-(2-Fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a Highly Potent and Efficacious Inhibitor

Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[( R )-2-methylpyrrolidin-2-yl]-1 H -benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

Alkynylatlon of aldehydic CH bonds via reaction with acetylenic triflones

Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1 H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer

Discovery and SAR of 2-(l-propylpiperidin-4-yl)-lH-benzimidazole-4-carboxamide : A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer

Alkynylation of C−H Bonds via Reaction with Acetylenic Triflones 1

Stereospecific Alkenylation of C−H Bonds via Reaction with β-Heteroatom-Functionalized Trisubstituted Vinyl Triflones 1

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