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From Cancer Biology to New Pulmonary Arterial Hypertension Therapeutics: Targeting Cell Growth and Proliferation Signaling Hubs

American journal of respiratory and critical care medicine, 2017-02, Vol.195 (4), p.425

2017

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mTOR Signaling Network in Cell Biology and Human Disease

International journal of molecular sciences, 2022-12, Vol.23 (24), p.16142

2022

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mTOR and vascular remodeling in lung diseases: current challenges and therapeutic prospects

The FASEB journal, 2013-05, Vol.27 (5), p.1796-1807

Goncharova, Elena A.

2013

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Stem Cell-derived Nanovesicles for the Treatment of Pulmonary Hypertension: Are We There Yet?

American journal of respiratory cell and molecular biology, 2022-07, Vol.67 (1), p.3-5

2022

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What Is All of the Hype About? Hypusine Signaling as a Driver of Pulmonary Hypertension

American journal of respiratory and critical care medicine, 2024-06, Vol.209 (11), p.1298

2024

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New Kid on the Block: GLI1+ Cells and Pulmonary Arterioles Neomuscularization

Circulation research, 2024-05, Vol.134 (11), p.1402

2024

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MonOrail to Cure? Targeting Orai1 to Reverse Pulmonary Arterial Hypertension

Circulation research, 2022-10, Vol.131 (9), p.728-730

2022

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Mammalian Target of Rapamycin Complex 2 (mTORC2) Coordinates Pulmonary Artery Smooth Muscle Cell Metabolism, Proliferation, and Survival in Pulmonary Arterial Hypertension

Circulation (New York, N.Y.), 2014-02, Vol.129 (8), p.864-874

2014

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Circling In on Pulmonary Arterial Hypertension: Is It Time to Consider Circular RNA circ_0016070 as a Biomarker and Target for Therapy?

Journal of the American Heart Association, 2022-07, Vol.11 (14), p.e026798-e026798

2022

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mTORC1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in IPF fibroblasts

Aging cell, 2016-12, Vol.15 (6), p.1103-1112

2016

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Too hot? Too cold? Wnt signalling in pulmonary arterial hypertension: can we treat it "just right"?

The European respiratory journal, 2023-06, Vol.61 (6), p.2300504

2023

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SIRT3-AMP-Activated Protein Kinase Activation by Nitrite and Metformin Improves Hyperglycemia and Normalizes Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction

Circulation (New York, N.Y.), 2016-02, Vol.133 (8), p.717-731

2016

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HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension

Scientific reports, 2017-07, Vol.7 (1), p.4546-14, Article 4546

2017

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Restoration of Lactobacillus johnsonii and Enterococcus faecalis Caused the Elimination of Tritrichomonas sp. in a Model of Antibiotic-Induced Dysbiosis

International journal of molecular sciences, 2024-05, Vol.25 (10), p.5090

2024

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Folliculin Controls Lung Alveolar Enlargement and Epithelial Cell Survival through E-Cadherin, LKB1, and AMPK

Cell reports (Cambridge), 2014-04, Vol.7 (2), p.412-423

2014

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Pharmacological Inhibition of mTOR Kinase Reverses Right Ventricle Remodeling and Improves Right Ventricle Structure and Function in Rats

American journal of respiratory cell and molecular biology, 2017-11, Vol.57 (5), p.615-625

2017

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Matrix Metalloproteinase-8 in Pulmonary Hypertension: The Sheep in the Wolf's Skin?

American journal of respiratory and critical care medicine, 2021-12, Vol.204 (12), p.1361-1363

2021

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Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation

Clinical science (1979), 2017-08, Vol.131 (15), p.2019

2017

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Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion

PloS one, 2012-11, Vol.7 (11), p.e47842-e47842

2012

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mTORC1 in Pulmonary Arterial Hypertension. At the Crossroads between Vasoconstriction and Vascular Remodeling?

American journal of respiratory and critical care medicine, 2020-05, Vol.201 (10), p.1177-1179

2020

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A Knockout of the IFITM3 Gene Increases the Sensitivity of WI-38 VA13 Cells to the Influenza A Virus

International journal of molecular sciences, 2024-01, Vol.25 (1), p.625

2024

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Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension

American journal of respiratory and critical care medicine, 2019-01, Vol.199 (2), p.199-210

2019

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Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension

Proceedings of the National Academy of Sciences - PNAS, 2021-04, Vol.118 (17), p.1

2021

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From Cancer Biology to New Pulmonary Arterial Hypertension Therapeutics: Targeting Cell Growth and Proliferation Signaling Hubs

mTOR Signaling Network in Cell Biology and Human Disease

mTOR and vascular remodeling in lung diseases: current challenges and therapeutic prospects

Stem Cell-derived Nanovesicles for the Treatment of Pulmonary Hypertension: Are We There Yet?

What Is All of the Hype About? Hypusine Signaling as a Driver of Pulmonary Hypertension

New Kid on the Block: GLI1+ Cells and Pulmonary Arterioles Neomuscularization

MonOrail to Cure? Targeting Orai1 to Reverse Pulmonary Arterial Hypertension

Mammalian Target of Rapamycin Complex 2 (mTORC2) Coordinates Pulmonary Artery Smooth Muscle Cell Metabolism, Proliferation, and Survival in Pulmonary Arterial Hypertension

Circling In on Pulmonary Arterial Hypertension: Is It Time to Consider Circular RNA circ_0016070 as a Biomarker and Target for Therapy?

mTORC1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in IPF fibroblasts

Too hot? Too cold? Wnt signalling in pulmonary arterial hypertension: can we treat it "just right"?

SIRT3-AMP-Activated Protein Kinase Activation by Nitrite and Metformin Improves Hyperglycemia and Normalizes Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction

HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension

Restoration of Lactobacillus johnsonii and Enterococcus faecalis Caused the Elimination of Tritrichomonas sp. in a Model of Antibiotic-Induced Dysbiosis

Folliculin Controls Lung Alveolar Enlargement and Epithelial Cell Survival through E-Cadherin, LKB1, and AMPK

Pharmacological Inhibition of mTOR Kinase Reverses Right Ventricle Remodeling and Improves Right Ventricle Structure and Function in Rats

Matrix Metalloproteinase-8 in Pulmonary Hypertension: The Sheep in the Wolf's Skin?

Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction

Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation

Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion

mTORC1 in Pulmonary Arterial Hypertension. At the Crossroads between Vasoconstriction and Vascular Remodeling?

A Knockout of the IFITM3 Gene Increases the Sensitivity of WI-38 VA13 Cells to the Influenza A Virus

Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension

Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival

Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension

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