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Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana

Marine drugs, 2021-06, Vol.19 (7), p.361

2021

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Identification of natural product modulators of Merkel cell carcinoma cell growth and survival

Scientific reports, 2021-06, Vol.11 (1), p.13597-10, Article 13597

2021

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A Molecular Networking Strategy: High-Throughput Screening and Chemical Analysis of Brazilian Cerrado Plant Extracts against Cancer Cells

Cells (Basel, Switzerland), 2021-03, Vol.10 (3), p.691

2021

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A high-throughput cell-based assay for inhibitors of ABCG2 activity

Journal of biomolecular screening, 2006-03, Vol.11 (2), p.176-183

2006

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cell-based high-throughput screen to identify synergistic TRAIL sensitizers

Cancer Immunology, Immunotherapy, 2009-08, Vol.58 (8), p.1229-1244

2009

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Photochemical Dimerization of Plakinidine B Leads to Potent Inhibition of the E3 Ubiquitin-Protein Ligase CBL‑B

Organic letters, 2022-12, Vol.24 (51), p.9468-9472

2022

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Development of a High-throughput NanoBRET Screening Platform to Identify Modulators of the RAS/RAF Interaction

Molecular cancer therapeutics, 2021-09, Vol.20 (9), p.1743-1754

2021

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The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation

Cell chemical biology, 2019-08, Vol.26 (8), p.1133-1142.e4

2019

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Chemoreactive 2,5-Diketopiperazines from a Penicillium sp., Structure Revision of Reported Analogues and Proposed Facile Transformation Pathways

Journal of natural products (Washington, D.C.), 2024-07, Vol.87 (7), p.1826-1837

2024

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Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases

Journal of natural products (Washington, D.C.), 2023-10, Vol.86 (10), p.2283-2293

2023

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Identification of potential modulators of osteosarcoma metastasis by high‐throughput cellular screening of natural products

Chemical biology & drug design, 2021-01, Vol.97 (1), p.77-86

2021

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Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3′,5′-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors

ACS pharmacology & translational science, 2023-04, Vol.6 (4), p.633-650

2023

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In Vitro Ubiquitination Platform Identifies Methyl Ellipticiniums as Ubiquitin Ligase Inhibitors

SLAS discovery, 2021-08, Vol.26 (7), p.870-884

2021

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Natural Products Active in Aberrant c-Kit Signaling

Chemical biology & drug design, 2007-05, Vol.69 (5), p.321-330

2007

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Discovery and Characterization of a Biologically Active Non-ATP-Competitive p38 MAP Kinase Inhibitor

Journal of biomolecular screening, 2016-03, Vol.21 (3), p.277-289

2016

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Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1)

SLAS discovery, 2017-10, Vol.22 (9), p.1093-1105

2017

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High-throughput Screening for Identification of Inhibitors of EpCAM-Dependent Growth of Hepatocellular Carcinoma Cells

Chemical biology & drug design, 2013-08, Vol.82 (2), p.131-139

2013

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Identification of compounds by high-content screening that induce cytoplasmic to nuclear localization of a fluorescent estrogen receptor α chimera and exhibit agonist or antagonist activity in vitro

Journal of biomolecular screening, 2014-02, Vol.19 (2), p.242-252

2014

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Development of a High-Throughput Cell-Based Reporter Assay to Identify Stabilizers of Tumor Suppressor Pdcd4

Journal of biomolecular screening, 2010-01, Vol.15 (1), p.21-29

2010

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A high-throughput cell-based assay to identify specific inhibitors of transcription factor AP-1

Journal of biomolecular screening, 2007-02, Vol.12 (1), p.133-139

2007

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A role for metallothionein and zinc in spontaneous mutagenesis

Cancer research (Chicago, Ill.), 1994-10, Vol.54 (20), p.5318-5323

1994

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Human cells lack the inducible tolerance to arsenite seen in hamster cells

Mutation Research-Reviews in Mutation Research, 1997-06, Vol.386 (3), p.307-314

1997

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Serum deprivation, but not inhibition of growth per se, induces a hypermutable state in Chinese hamster G12 cells

Cancer research (Chicago, Ill.), 1996-02, Vol.56 (4), p.752-756

1996

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High‐throughput Screening for Identification of Inhibitors of Ep CAM ‐Dependent Growth of Hepatocellular Carcinoma Cells

Chemical biology & drug design, 2013-08, Vol.82 (2), p.131-139

2013

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Mutations and infinity: Improved statistical methods for estimating spontaneous rates

Environmental and molecular mutagenesis, 1996, Vol.28 (2), p.90-99

1996

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Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana

Identification of natural product modulators of Merkel cell carcinoma cell growth and survival

A Molecular Networking Strategy: High-Throughput Screening and Chemical Analysis of Brazilian Cerrado Plant Extracts against Cancer Cells

A high-throughput cell-based assay for inhibitors of ABCG2 activity

cell-based high-throughput screen to identify synergistic TRAIL sensitizers

Photochemical Dimerization of Plakinidine B Leads to Potent Inhibition of the E3 Ubiquitin-Protein Ligase CBL‑B

Development of a High-throughput NanoBRET Screening Platform to Identify Modulators of the RAS/RAF Interaction

The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation

Chemoreactive 2,5-Diketopiperazines from a Penicillium sp., Structure Revision of Reported Analogues and Proposed Facile Transformation Pathways

Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases

Identification of potential modulators of osteosarcoma metastasis by high‐throughput cellular screening of natural products

Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3′,5′-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors

In Vitro Ubiquitination Platform Identifies Methyl Ellipticiniums as Ubiquitin Ligase Inhibitors

Natural Products Active in Aberrant c-Kit Signaling

Discovery and Characterization of a Biologically Active Non-ATP-Competitive p38 MAP Kinase Inhibitor

Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1)

High-throughput Screening for Identification of Inhibitors of EpCAM-Dependent Growth of Hepatocellular Carcinoma Cells

Identification of compounds by high-content screening that induce cytoplasmic to nuclear localization of a fluorescent estrogen receptor α chimera and exhibit agonist or antagonist activity in vitro

Development of a High-Throughput Cell-Based Reporter Assay to Identify Stabilizers of Tumor Suppressor Pdcd4

A high-throughput cell-based assay to identify specific inhibitors of transcription factor AP-1

A role for metallothionein and zinc in spontaneous mutagenesis

Human cells lack the inducible tolerance to arsenite seen in hamster cells

Serum deprivation, but not inhibition of growth per se, induces a hypermutable state in Chinese hamster G12 cells

High‐throughput Screening for Identification of Inhibitors of Ep CAM ‐Dependent Growth of Hepatocellular Carcinoma Cells

Mutations and infinity: Improved statistical methods for estimating spontaneous rates

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