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Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells

Cell, 2016-08, Vol.166 (4), p.894-906

2016

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Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators

Cell stem cell, 2016-10, Vol.19 (4), p.530-543

2016

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Plexin-B2 Mediates Physiologic and Pathologic Functions of Angiogenin

Cell, 2017-11, Vol.171 (4), p.849-864.e25

2017

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Angiogenin and plexin-B2 axis promotes glioblastoma progression by enhancing invasion, vascular association, proliferation and survival

British journal of cancer, 2022-08, Vol.127 (3), p.422-435

2022

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Quantifiable and reproducible phenotypic assessment of a constitutive knockout mouse model for congenital nephrotic syndrome of the Finnish type

Scientific reports, 2024-07, Vol.14 (1), p.15916-9, Article 15916

2024

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Quantitative phenotyping of Nphs1 knockout mice as a prerequisite for gene replacement studies

American journal of physiology. Renal physiology, 2024-05, Vol.326 (5), p.F780

2024

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Phenotypic quantification of Nphs1-deficient mice

Journal of nephrology, 2024-07

2024

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Chemosensitization of prostate cancer stem cells in mice by angiogenin and plexin-B2 inhibitors

Communications biology, 2020-01, Vol.3 (1), p.26-26, Article 26

2020

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Correction to: Phenotypic quantification of Nphs1‑deficient mice

Journal of nephrology, 2024-08

2024

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Single-dose MGTA-145/plerixafor leads to efficient mobilization and in vivo transduction of HSCs with thalassemia correction in mice

Blood advances, 2021-03, Vol.5 (5), p.1239-1249

2021

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Mgta-145 / Plerixafor-Mediated HSC Mobilization and Intravenous HDAd5/35++ Vector Injection into Mice Allows for Efficient In Vivo HSC Transduction and Stable Gene Marking in Peripheral Blood Cells of CD46-Transgenic and Thalassemia Mice

Blood, 2020-11, Vol.136 (Supplement 1), p.4-5

2020

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Mgta-456 Contains Large Numbers of Expanded Cord Blood (CB) CD34+CD90+ Hematopoietic Stem Cells (HSC) Which Confer All Engraftment Activity and Correlate with Accelerated Neutrophil Recovery after Myeloablative Conditioning in Patients with Hematologic Malignancy

Blood, 2018-11, Vol.132 (Supplement 1), p.2083-2083

2018

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Ex Vivo Expansion with E478 Increases the Rate of CRISPR-Mediated Homology Directed Repair of the Beta-Globin Gene in Human Hematopoietic Stem Cells By >10-Fold and Improves In Vivo Engraftment By >120-Fold

Blood, 2019-11, Vol.134 (Supplement_1), p.4634-4634

2019

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High Dose Hematopoietic Stem Cell Transplantation Leads to Rapid Hematopoietic and Microglia Recovery and Disease Correction in a Mouse Model of Hurler Syndrome

Blood, 2019-11, Vol.134 (Supplement_1), p.4424-4424

2019

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TIP: A phase I/II study of MGTA-117, an anti-CD117 antibody-drug conjugate, in patients with adult acute myeloid leukemia (AML) and myelodysplasia with excess blasts (MDS-EB)

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.TPS3156-TPS3156

2022

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MGTA-145 in Combination with Plerixafor Rapidly Mobilizes High Numbers of Hematopoietic Stem Cells and Graft-Versus-Host Disease Inhibiting Myeloid-Derived Suppressor Cells in Non-Human Primates

Blood, 2018-11, Vol.132 (Supplement 1), p.116-116

2018

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MGTA-456, a First-in-Class Cell Therapy Produced from a Single Cord Blood Unit, Enables a Reduced Intensity Conditioning Regimen and Enhances Speed and Level of Human Microglia Engraftment in the Brains of NSG Mice

Blood, 2018-11, Vol.132 (Supplement 1), p.115-115

2018

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Mgta-145, in Combination with Plerixafor in a Phase 1 Clinical Trial, Mobilizes Large Numbers of Human Hematopoietic Stem Cells and a Graft with Immunosuppressive Effects for Allogeneic Transplant

Blood, 2020-11, Vol.136 (Supplement 1), p.31-32

2020

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The Combination of GROβ and AMD3100 Leads to Rapid and Robust Mobilization of Hematopoietic Stem Cells in Nonhuman Primates

Blood, 2017-12, Vol.130, p.1920-1920

2017

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Mgta-145 + Plerixafor Provides GCSF-Free Rapid and Reliable Hematopoietic Stem Cell Mobilization for Autologous Stem Cell Transplant in Patients with Multiple Myeloma: A Phase 2 Study

Blood, 2021-11, Vol.138 (Supplement 1), p.3885-3885

2021

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MGTA-456, a first-in-class cell therapy that enables a reduced intensity conditioning regimen and enhances speed and level of human microglia engraftment in the brains of NSG mice

Molecular genetics and metabolism, 2019-02, Vol.126 (2), p.S62-S62

2019

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Phase 2 study of MGTA-145 + plerixafor for rapid and reliable hematopoietic stem cell (HSC) mobilization for autologous transplant in multiple myeloma

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.8023-8023

2021

Volltextzugriff (PDF)

High dose hematopoietic stem cell transplantation leads to rapid hematopoietic and microglial recovery and disease correction in a mouse model of Hurler syndrome

Molecular genetics and metabolism, 2020-02, Vol.129 (2), p.S123-S123

2020

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Rapid and Robust Mobilization of CD34+ HSCs without G-CSF Following Administration of Mgta-145 Alone or in Combination with Plerixafor

Blood, 2019-11, Vol.134 (Supplement_1), p.1961-1961

2019

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Aryl Hydrocarbon Receptor Antagonists Expand Adult Hematopoietic Stem Cells from Mobilized Peripheral Blood and Bone Marrow and Increase the Dose of CRISPR/Cas9 Gene-Edited NSG-Repopulating Cells

Blood, 2017-12, Vol.130, p.3341-3341

2017

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Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells

Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators

Plexin-B2 Mediates Physiologic and Pathologic Functions of Angiogenin

Angiogenin and plexin-B2 axis promotes glioblastoma progression by enhancing invasion, vascular association, proliferation and survival

Quantifiable and reproducible phenotypic assessment of a constitutive knockout mouse model for congenital nephrotic syndrome of the Finnish type

Quantitative phenotyping of Nphs1 knockout mice as a prerequisite for gene replacement studies

Phenotypic quantification of Nphs1-deficient mice

Chemosensitization of prostate cancer stem cells in mice by angiogenin and plexin-B2 inhibitors

Correction to: Phenotypic quantification of Nphs1‑deficient mice

Single-dose MGTA-145/plerixafor leads to efficient mobilization and in vivo transduction of HSCs with thalassemia correction in mice

Mgta-145 / Plerixafor-Mediated HSC Mobilization and Intravenous HDAd5/35++ Vector Injection into Mice Allows for Efficient In Vivo HSC Transduction and Stable Gene Marking in Peripheral Blood Cells of CD46-Transgenic and Thalassemia Mice

Mgta-456 Contains Large Numbers of Expanded Cord Blood (CB) CD34+CD90+ Hematopoietic Stem Cells (HSC) Which Confer All Engraftment Activity and Correlate with Accelerated Neutrophil Recovery after Myeloablative Conditioning in Patients with Hematologic Malignancy

Ex Vivo Expansion with E478 Increases the Rate of CRISPR-Mediated Homology Directed Repair of the Beta-Globin Gene in Human Hematopoietic Stem Cells By >10-Fold and Improves In Vivo Engraftment By >120-Fold

High Dose Hematopoietic Stem Cell Transplantation Leads to Rapid Hematopoietic and Microglia Recovery and Disease Correction in a Mouse Model of Hurler Syndrome

TIP: A phase I/II study of MGTA-117, an anti-CD117 antibody-drug conjugate, in patients with adult acute myeloid leukemia (AML) and myelodysplasia with excess blasts (MDS-EB)

MGTA-145 in Combination with Plerixafor Rapidly Mobilizes High Numbers of Hematopoietic Stem Cells and Graft-Versus-Host Disease Inhibiting Myeloid-Derived Suppressor Cells in Non-Human Primates

MGTA-456, a First-in-Class Cell Therapy Produced from a Single Cord Blood Unit, Enables a Reduced Intensity Conditioning Regimen and Enhances Speed and Level of Human Microglia Engraftment in the Brains of NSG Mice

Mgta-145, in Combination with Plerixafor in a Phase 1 Clinical Trial, Mobilizes Large Numbers of Human Hematopoietic Stem Cells and a Graft with Immunosuppressive Effects for Allogeneic Transplant

The Combination of GROβ and AMD3100 Leads to Rapid and Robust Mobilization of Hematopoietic Stem Cells in Nonhuman Primates

Mgta-145 + Plerixafor Provides GCSF-Free Rapid and Reliable Hematopoietic Stem Cell Mobilization for Autologous Stem Cell Transplant in Patients with Multiple Myeloma: A Phase 2 Study

MGTA-456, a first-in-class cell therapy that enables a reduced intensity conditioning regimen and enhances speed and level of human microglia engraftment in the brains of NSG mice

Phase 2 study of MGTA-145 + plerixafor for rapid and reliable hematopoietic stem cell (HSC) mobilization for autologous transplant in multiple myeloma

High dose hematopoietic stem cell transplantation leads to rapid hematopoietic and microglial recovery and disease correction in a mouse model of Hurler syndrome

Rapid and Robust Mobilization of CD34+ HSCs without G-CSF Following Administration of Mgta-145 Alone or in Combination with Plerixafor

Aryl Hydrocarbon Receptor Antagonists Expand Adult Hematopoietic Stem Cells from Mobilized Peripheral Blood and Bone Marrow and Increase the Dose of CRISPR/Cas9 Gene-Edited NSG-Repopulating Cells

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