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A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins

Cell, 2015-03, Vol.161 (1), p.161-172

2015

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Retrospective on Cholesterol Homeostasis: The Central Role of Scap

Annual review of biochemistry, 2018-06, Vol.87 (1), p.783-807

2018

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The LDL receptor

Arteriosclerosis, thrombosis, and vascular biology, 2009-04, Vol.29 (4), p.431-438

2009

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Selective versus Total Insulin Resistance: A Pathogenic Paradox

Cell metabolism, 2008-02, Vol.7 (2), p.95-96

2008

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Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (8), p.3441-3446

2010

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Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL

Journal of lipid research, 2009-04, Vol.50 (Suppl), p.S15-S27

2009

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The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals

Cell metabolism, 2012-02, Vol.15 (2), p.240-246

2012

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What Makes a Piece of Art or Science a Masterpiece?

Cell, 2018-09, Vol.175 (1), p.1-5

Goldstein, Joseph L.

2018

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Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (31), p.18521-18529

2020

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Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis

eLife, 2014-06, Vol.3

2014

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Induced Ablation of Ghrelin Cells in Adult Mice Does Not Decrease Food Intake, Body Weight, or Response to High-Fat Diet

Cell metabolism, 2014-07, Vol.20 (1), p.54-60

2014

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Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection

eLife, 2015-12, Vol.4

2015

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Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

Cell, 2009-06, Vol.137 (7), p.1213-1224

2009

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Switch-like Control of SREBP-2 Transport Triggered by Small Changes in ER Cholesterol: A Delicate Balance

Cell metabolism, 2008-12, Vol.8 (6), p.512-521

2008

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Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (40), p.16184-16189

2012

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Unexpected role for IGF-1 in starvation: Maintenance of blood glucose

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (32), p.e2208855119-e2208855119

2022

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Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig

Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (16), p.6511-6518

2007

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Growth hormone acts on liver to stimulate autophagy, support glucose production, and preserve blood glucose in chronically starved mice

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (15), p.7449-7454

2019

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

The Journal of clinical investigation, 2002-05, Vol.109 (9), p.1125-1131

2002

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Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (16), p.7467-7472

2010

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Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol

Proceedings of the National Academy of Sciences - PNAS, 2022-01, Vol.119 (2)

2022

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NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (40), p.15287-15292

2008

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Reduced autophagy in livers of fasted, fat-depleted, ghrelin-deficient mice: Reversal by growth hormone

Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (4), p.1226-1231

2015

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Use of mutant ¹²⁵I-Perfringolysin O to probe transport and organization of cholesterol in membranes of animal cells

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (26), p.10580-10585

2013

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Identification of Surface Residues on Niemann-Pick C2 Essential for Hydrophobic Handoff of Cholesterol to NPC1 in Lysosomes

Cell metabolism, 2010-08, Vol.12 (2), p.166-173

2010

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A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins

Retrospective on Cholesterol Homeostasis: The Central Role of Scap

The LDL receptor

Selective versus Total Insulin Resistance: A Pathogenic Paradox

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL

The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals

What Makes a Piece of Art or Science a Masterpiece?

Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine

Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis

Induced Ablation of Ghrelin Cells in Adult Mice Does Not Decrease Food Intake, Body Weight, or Response to High-Fat Diet

Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection

Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

Switch-like Control of SREBP-2 Transport Triggered by Small Changes in ER Cholesterol: A Delicate Balance

Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase

Unexpected role for IGF-1 in starvation: Maintenance of blood glucose

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig

Growth hormone acts on liver to stimulate autophagy, support glucose production, and preserve blood glucose in chronically starved mice

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice

Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

Reduced autophagy in livers of fasted, fat-depleted, ghrelin-deficient mice: Reversal by growth hormone

Use of mutant ¹²⁵I-Perfringolysin O to probe transport and organization of cholesterol in membranes of animal cells

Identification of Surface Residues on Niemann-Pick C2 Essential for Hydrophobic Handoff of Cholesterol to NPC1 in Lysosomes

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