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Protein degradation and protection against misfolded or damaged proteins

Nature (London), 2003-12, Vol.426 (6968), p.895-899

Goldberg, Alfred L

2003

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Importance of the Different Proteolytic Sites of the Proteasome and the Efficacy of Inhibitors Varies with the Protein Substrate

The Journal of biological chemistry, 2006-03, Vol.281 (13), p.8582-8590

2006

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Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy

Cell, 2004-04, Vol.117 (3), p.399-412

2004

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Muscle Wasting in Aged, Sarcopenic Rats Is Associated with Enhanced Activity of the Ubiquitin Proteasome Pathway

The Journal of biological chemistry, 2010-12, Vol.285 (51), p.39597-39608

2010

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Cellular Defenses against Unfolded Proteins: A Cell Biologist Thinks about Neurodegenerative Diseases

Neuron, 2001, Vol.29 (1), p.15-32

2001

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IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1

American journal of physiology: endocrinology and metabolism, 2004-10, Vol.287 (4), p.E591-E601

2004

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Atrogin-1, A Muscle-Specific F-Box Protein Highly Expressed during Muscle Atrophy

Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (25), p.14440-14445

2001

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Eukaryotic Proteasomes Cannot Digest Polyglutamine Sequences and Release Them during Degradation of Polyglutamine-Containing Proteins

Molecular cell, 2004-04, Vol.14 (1), p.95-104

2004

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Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

The FASEB journal, 2004-01, Vol.18 (1), p.39-51

2004

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Trehalose Synthesis is Induced upon Exposure of Escherichia coli to Cold and is Essential for Viability at Low Temperatures

Proceedings of the National Academy of Sciences - PNAS, 2002-07, Vol.99 (15), p.9727-9732

2002

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Proteasome inhibitors: valuable new tools for cell biologists

Trends in cell biology, 1998-10, Vol.8 (10), p.397-403

1998

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Trehalose Accumulation during Cellular Stress Protects Cells and Cellular Proteins from Damage by Oxygen Radicals

The Journal of biological chemistry, 2001-06, Vol.276 (26), p.24261-24267

2001

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ATP Binding to PAN or the 26S ATPases Causes Association with the 20S Proteasome, Gate Opening, and Translocation of Unfolded Proteins

Molecular cell, 2005-12, Vol.20 (5), p.687-698

2005

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Post-proteasomal antigen processing for major histocompatibility complex class I presentation

Nature immunology, 2004-07, Vol.5 (7), p.670-677

2004

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DEGRADATION OF CELL PROTEINS AND THE GENERATION OF MHC CLASS I-PRESENTED PEPTIDES

Annual review of immunology, 1999-01, Vol.17 (1), p.739-779

1999

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Proteins Are Unfolded on the Surface of the ATPase Ring before Transport into the Proteasome

Molecular cell, 2001-12, Vol.8 (6), p.1339-1349

2001

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The FOXO3a Transcription Factor Regulates Cardiac Myocyte Size Downstream of AKT Signaling

The Journal of biological chemistry, 2005-05, Vol.280 (21), p.20814-20823

2005

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Structure and Functions of the 20S and 26S Proteasomes

Annual review of biochemistry, 1996-01, Vol.65 (1), p.801-847

1996

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Yeast Adapt to Near-Freezing Temperatures by STRE/Msn2,4-Dependent Induction of Trehalose Synthesis and Certain Molecular Chaperones

Molecular cell, 2004-03, Vol.13 (6), p.771-781

2004

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Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases

The Journal of biological chemistry, 2004-11, Vol.279 (45), p.46723-46732

2004

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Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states

The Journal of nutrition, 1999, Vol.129 (1S), p.227S-237S

1999

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The Axial Channel of the Proteasome Core Particle Is Gated by the Rpt2 ATPase and Controls Both Substrate Entry and Product Release

Molecular cell, 2001-06, Vol.7 (6), p.1143-1152

2001

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An IFN-γ-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

Nature immunology, 2002-12, Vol.3 (12), p.1169-1176

2002

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What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?

Current opinion in clinical nutrition and metabolic care, 2001-05, Vol.4 (3), p.183-190

2001

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Patterns of gene expression in atrophying skeletal muscles: response to food deprivation

The FASEB journal, 2002-11, Vol.16 (13), p.1697-1712

2002

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Protein degradation and protection against misfolded or damaged proteins

Importance of the Different Proteolytic Sites of the Proteasome and the Efficacy of Inhibitors Varies with the Protein Substrate

Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy

Muscle Wasting in Aged, Sarcopenic Rats Is Associated with Enhanced Activity of the Ubiquitin Proteasome Pathway

Cellular Defenses against Unfolded Proteins: A Cell Biologist Thinks about Neurodegenerative Diseases

IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1

Atrogin-1, A Muscle-Specific F-Box Protein Highly Expressed during Muscle Atrophy

Eukaryotic Proteasomes Cannot Digest Polyglutamine Sequences and Release Them during Degradation of Polyglutamine-Containing Proteins

Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

Trehalose Synthesis is Induced upon Exposure of Escherichia coli to Cold and is Essential for Viability at Low Temperatures

Proteasome inhibitors: valuable new tools for cell biologists

Trehalose Accumulation during Cellular Stress Protects Cells and Cellular Proteins from Damage by Oxygen Radicals

ATP Binding to PAN or the 26S ATPases Causes Association with the 20S Proteasome, Gate Opening, and Translocation of Unfolded Proteins

Post-proteasomal antigen processing for major histocompatibility complex class I presentation

DEGRADATION OF CELL PROTEINS AND THE GENERATION OF MHC CLASS I-PRESENTED PEPTIDES

Proteins Are Unfolded on the Surface of the ATPase Ring before Transport into the Proteasome

The FOXO3a Transcription Factor Regulates Cardiac Myocyte Size Downstream of AKT Signaling

Structure and Functions of the 20S and 26S Proteasomes

Yeast Adapt to Near-Freezing Temperatures by STRE/Msn2,4-Dependent Induction of Trehalose Synthesis and Certain Molecular Chaperones

Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases

Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states

The Axial Channel of the Proteasome Core Particle Is Gated by the Rpt2 ATPase and Controls Both Substrate Entry and Product Release

An IFN-γ-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?

Patterns of gene expression in atrophying skeletal muscles: response to food deprivation

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