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Enantioselective Synthesis of cis-3-Fluoropiperidin-4-ol, a Building Block for Medicinal Chemistry

Journal of organic chemistry, 2013-09, Vol.78 (17), p.8892-8897

2013

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Diverse alkaloid-like structures from a common building block

Tetrahedron, 2013-01, Vol.69 (1), p.242-256

Goff, Dane A.

2013

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Optimization of Pharmacokinetic and In Vitro Safety Profile of a Series of Pyridine Diamide Indirect AMPK Activators

Journal of medicinal chemistry, 2023-12, Vol.66 (24), p.17086-17104

2023

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Structure activity relationships leading to the identification of the indirect activator of AMPK, R419

Bioorganic & medicinal chemistry, 2022-10, Vol.71, p.116951-116951, Article 116951

2022

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Developing DYRK inhibitors derived from the meridianins as a means of increasing levels of NFAT in the nucleus

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (11), p.2617-2621

2017

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Discovery and Characterization of Substituted Diphenyl Heterocyclic Compounds as Potent and Selective Inhibitors of Hepatitis C Virus Replication

Antimicrobial Agents and Chemotherapy, 2008-04, Vol.52 (4), p.1419-1429

2008

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Global metabolite profiling of mice with high-fat diet-induced obesity chronically treated with AMPK activators R118 or metformin reveals tissue-selective alterations in metabolic pathways

BMC research notes, 2014-09, Vol.7 (1), p.674-674, Article 674

2014

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Efforts towards a Noyori reduction of a 3-fluorpiperidin-4-one with dynamic kinetic resolution

Tetrahedron letters, 2021-03, Vol.66, p.152764, Article 152764

2021

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Solid-phase synthesis of defined 1,4-benzodiazepine-2,5-dione mixtures

Journal of organic chemistry, 1995-09, Vol.60 (18), p.5744-5745

1995

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Discovery of Nanomolar Ligands for 7-Transmembrane G-Protein-Coupled Receptors from a Diverse N-(Substituted)glycine Peptoid Library

Journal of medicinal chemistry, 1994-08, Vol.37 (17), p.2678-2685

1994

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Solid-Phase Synthesis of Highly Substituted Peptoid 1(2H)-Isoquinolinones

Journal of organic chemistry, 1995-09, Vol.60 (18), p.5748-5749

1995

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The synthesis of 2-oxopiperazines by intramolecular Michael addition on solid support

Tetrahedron letters, 1996-08, Vol.37 (35), p.6247-6250

1996

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The meso substitution of chlorophyll derivatives: direct route for transformation of bacteriopheophorbides d into bacteriopheophorbides c

Journal of the American Chemical Society, 1985-08, Vol.107 (17), p.4946-4954

1985

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NMR spectra of porphyrins. 28. Detailed solution structure of a bacteriochlorophyllide d dimer

Journal of the American Chemical Society, 1986-03, Vol.108 (6), p.1111-1120

1986

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Synthesis of nickel(II) isobacteriochlorins from nickel(II) complexes of chlorophyll derivatives

Journal of the American Chemical Society, 1985-08, Vol.107 (17), p.4954-4964

1985

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Intermediates in the formation of the chlorophyll isocyclic ring

Plant physiology (Bethesda), 1985-11, Vol.79 (3), p.725-729

1985

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Isolation and characterization of two new bacteriochlorophylls d bearing neopentyl substituents

Journal of the American Chemical Society, 1983-03, Vol.105 (6), p.1674-1676

1983

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NMR structural characterization of oligo-N-substituted glycine lead compounds from a combinatorial library

Molecular diversity, 1997, Vol.3 (1), p.1-15

1997

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Bacteriochlorophylls-d from Chlorobium vibrioforme: chromatographic separations and structural assignments of the methyl bacteriopheophorbides

Journal of the Chemical Society, Perkin Transactions 1, 1985, p.1099

1985

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ChemInform Abstract: Enantioselective Synthesis of cis-3-Fluoropiperidin-4-ol, a Building Block for Medicinal Chemistry

ChemInform, 2014-02, Vol.45 (6), p.no-no

2014

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Substituted 2-iminothiolanes: reagents for the preparation of disulfide cross-linked conjugates with increased stability

Bioconjugate chemistry, 1990-11, Vol.1 (6), p.381-386

1990

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Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 2. Preparation and in vitro and in vivo evaluaton of 1-(alkoxymethyl)-2-[(hydroxyimino)methyl]-3-methylimidazolium halides for reactivation of organophosphorus-inhibited acetylcholinesterases

Journal of medicinal chemistry, 1989-02, Vol.32 (2), p.493-503

1989

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NMR spectra of porphyrins. Part 31. Ring currents in hydroporphyrins

Journal of the American Chemical Society, 1987-08, Vol.109 (16), p.4786-4791

1987

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Enantioselective Synthesis of cis-3-Fluoropiperidin-4-ol, a Building Block for Medicinal Chemistry

Diverse alkaloid-like structures from a common building block

Optimization of Pharmacokinetic and In Vitro Safety Profile of a Series of Pyridine Diamide Indirect AMPK Activators

Structure activity relationships leading to the identification of the indirect activator of AMPK, R419

Developing DYRK inhibitors derived from the meridianins as a means of increasing levels of NFAT in the nucleus

AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes

Discovery and Characterization of Substituted Diphenyl Heterocyclic Compounds as Potent and Selective Inhibitors of Hepatitis C Virus Replication

Global metabolite profiling of mice with high-fat diet-induced obesity chronically treated with AMPK activators R118 or metformin reveals tissue-selective alterations in metabolic pathways

Efforts towards a Noyori reduction of a 3-fluorpiperidin-4-one with dynamic kinetic resolution

Solid-phase synthesis of defined 1,4-benzodiazepine-2,5-dione mixtures

Discovery of Nanomolar Ligands for 7-Transmembrane G-Protein-Coupled Receptors from a Diverse N-(Substituted)glycine Peptoid Library

Solid-Phase Synthesis of Highly Substituted Peptoid 1(2H)-Isoquinolinones

The synthesis of 2-oxopiperazines by intramolecular Michael addition on solid support

The meso substitution of chlorophyll derivatives: direct route for transformation of bacteriopheophorbides d into bacteriopheophorbides c

NMR spectra of porphyrins. 28. Detailed solution structure of a bacteriochlorophyllide d dimer

Synthesis of nickel(II) isobacteriochlorins from nickel(II) complexes of chlorophyll derivatives

Intermediates in the formation of the chlorophyll isocyclic ring

Isolation and characterization of two new bacteriochlorophylls d bearing neopentyl substituents

NMR structural characterization of oligo-N-substituted glycine lead compounds from a combinatorial library

Bacteriochlorophylls-d from Chlorobium vibrioforme: chromatographic separations and structural assignments of the methyl bacteriopheophorbides

ChemInform Abstract: Enantioselective Synthesis of cis-3-Fluoropiperidin-4-ol, a Building Block for Medicinal Chemistry

Substituted 2-iminothiolanes: reagents for the preparation of disulfide cross-linked conjugates with increased stability

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 2. Preparation and in vitro and in vivo evaluaton of 1-(alkoxymethyl)-2-[(hydroxyimino)methyl]-3-methylimidazolium halides for reactivation of organophosphorus-inhibited acetylcholinesterases

AMPK activation by a novel small molecule of mitochondrial regulation enhances fatty acid oxidation, ketogenesis and branched chain amino acid catabolism in vivo

NMR spectra of porphyrins. Part 31. Ring currents in hydroporphyrins

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