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GPR65 as a potential novel therapeutic target for the treatment of hepatic fibrosis

Military medical research, 2024-01, Vol.11 (1), p.4-4, Article 4

Gobejishvili, Leila

2024

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Role of cAMP and phosphodiesterase signaling in liver health and disease

Cellular signalling, 2018-09, Vol.49, p.105-115

2018

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Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment

PloS one, 2013-01, Vol.8 (1), p.e53028

2013

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Keratin 18 Is a Diagnostic and Prognostic Factor for Acute Alcoholic Hepatitis

Clinical gastroenterology and hepatology, 2020-08, Vol.18 (9), p.2046-2054

2020

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cAMP Signaling in Pathobiology of Alcohol Associated Liver Disease

Biomolecules (Basel, Switzerland), 2020-10, Vol.10 (10), p.1433

2020

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Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia

Neurobiology of disease, 2019-04, Vol.124, p.353-363

2019

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Palmitic acid induces production of proinflammatory cytokine interleukin‐8 from hepatocytes

Hepatology (Baltimore, Md.), 2007-09, Vol.46 (3), p.823-830

2007

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Urinary acrolein metabolite levels in severe acute alcoholic hepatitis patients

American journal of physiology: Gastrointestinal and liver physiology, 2019-01, Vol.316 (1), p.G115-G122

2019

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Decrease in acetyl-CoA pathway utilizing butyrate-producing bacteria is a key pathogenic feature of alcohol-induced functional gut microbial dysbiosis and development of liver disease in mice

Gut microbes, 2021-01, Vol.13 (1), p.1946367-1946367

2021

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Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells

BMC cancer, 2018-04, Vol.18 (1), p.421-421, Article 421

2018

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Pathophysiology of Gastroparesis Syndromes Includes Anatomic and Physiologic Abnormalities

Digestive diseases and sciences, 2021-04, Vol.66 (4), p.1127-1141

2021

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Phosphodiesterase 4b expression plays a major role in alcohol-induced neuro-inflammation

Neuropharmacology, 2017-10, Vol.125, p.376-385

2017

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Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease

The Journal of nutritional biochemistry, 2011-01, Vol.22 (1), p.38-45

2011

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Hepatocyte-specific mitogen-activated protein kinase phosphatase 1 in sexual dimorphism and susceptibility to alcohol induced liver injury

Frontiers in immunology, 2024-02, Vol.15, p.1316228-1316228

2024

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Correction to: Pathophysiology of Gastroparesis Syndromes Includes Anatomic and Physiologic Abnormalities

Digestive diseases and sciences, 2021-05, Vol.66 (5), p.1765-1765

2021

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Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease

American journal of physiology: Gastrointestinal and liver physiology, 2008-10, Vol.295 (4), p.G718-G724

2008

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Dysregulated Cyclic Nucleotide Metabolism in Alcohol-Associated Steatohepatitis: Implications for Novel Targeted Therapies

Biology (Basel, Switzerland), 2023-10, Vol.12 (10), p.1321

2023

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Association of Circulating Markers of Microbial Translocation and Hepatic Inflammation with Liver Injury in Patients with Type 2 Diabetes

Biomedicines, 2024-06, Vol.12 (6), p.1227

2024

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Histone modifications and alcohol-induced liver disease： Are altered nutrients the missing link

World journal of gastroenterology : WJG, 2011-05, Vol.17 (20), p.2465-2472

2011

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Elevated Fructose and Uric Acid Through Aldose Reductase Contribute to Experimental and Human Alcoholic Liver Disease

Hepatology (Baltimore, Md.), 2020-11, Vol.72 (5), p.1617-1637

2020

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Alcohol‐Induced ICAM‐1 And VCAM‐1 Promote Hepatic Leukocyte Infiltration And Are Biomarkers For Mortality Prediction In Alcohol‐Associated Hepatitis

The FASEB journal, 2021-05, Vol.35, p.n/a

2021

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Increased hepatic JNK activation by ethanol is mediated by transcriptional suppression of mitogen‐activated protein kinase phosphatase 1 (Mkp1): role of cAMP‐specific protein kinase A

The FASEB journal, 2021-05, Vol.35 (S1), p.n/a, Article fasebj.2021.35.S1.03948

2021

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Increased expression of phosphodiesterase 4 in activated hepatic stellate cells promotes cytoskeleton remodeling and cell migration

The Journal of pathology, 2023-11, Vol.261 (3), p.361-371

2023

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Su1692 DECREASED RHO KINASE SIGNALING AND CONTRACTILITY OF HEPATIC STELLATE CELLS BY PDE4 INHIBITOR ATTENUATES FIBROTIC PATHWAYS IN VIVO AND IN VITRO

Gastroenterology (New York, N.Y. 1943), 2020-05, Vol.158 (6), p.S-1384-S-1384

2020

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Attenuation of fibrogenesis by PDE4 inhibitor via decreased cytoskeleton remodeling, activation and contractility of hepatic stellate cells

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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GPR65 as a potential novel therapeutic target for the treatment of hepatic fibrosis

Role of cAMP and phosphodiesterase signaling in liver health and disease

Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment

Keratin 18 Is a Diagnostic and Prognostic Factor for Acute Alcoholic Hepatitis

cAMP Signaling in Pathobiology of Alcohol Associated Liver Disease

Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia

Palmitic acid induces production of proinflammatory cytokine interleukin‐8 from hepatocytes

Urinary acrolein metabolite levels in severe acute alcoholic hepatitis patients

Decrease in acetyl-CoA pathway utilizing butyrate-producing bacteria is a key pathogenic feature of alcohol-induced functional gut microbial dysbiosis and development of liver disease in mice

Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells

Pathophysiology of Gastroparesis Syndromes Includes Anatomic and Physiologic Abnormalities

Phosphodiesterase 4b expression plays a major role in alcohol-induced neuro-inflammation

Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease

Hepatocyte-specific mitogen-activated protein kinase phosphatase 1 in sexual dimorphism and susceptibility to alcohol induced liver injury

Correction to: Pathophysiology of Gastroparesis Syndromes Includes Anatomic and Physiologic Abnormalities

Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease

Dysregulated Cyclic Nucleotide Metabolism in Alcohol-Associated Steatohepatitis: Implications for Novel Targeted Therapies

Association of Circulating Markers of Microbial Translocation and Hepatic Inflammation with Liver Injury in Patients with Type 2 Diabetes

Histone modifications and alcohol-induced liver disease： Are altered nutrients the missing link

Elevated Fructose and Uric Acid Through Aldose Reductase Contribute to Experimental and Human Alcoholic Liver Disease

Alcohol‐Induced ICAM‐1 And VCAM‐1 Promote Hepatic Leukocyte Infiltration And Are Biomarkers For Mortality Prediction In Alcohol‐Associated Hepatitis

Increased hepatic JNK activation by ethanol is mediated by transcriptional suppression of mitogen‐activated protein kinase phosphatase 1 (Mkp1): role of cAMP‐specific protein kinase A

Increased expression of phosphodiesterase 4 in activated hepatic stellate cells promotes cytoskeleton remodeling and cell migration

Su1692 DECREASED RHO KINASE SIGNALING AND CONTRACTILITY OF HEPATIC STELLATE CELLS BY PDE4 INHIBITOR ATTENUATES FIBROTIC PATHWAYS IN VIVO AND IN VITRO

Attenuation of fibrogenesis by PDE4 inhibitor via decreased cytoskeleton remodeling, activation and contractility of hepatic stellate cells

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