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Synthesis and Biophysical and Biological Studies of N‑Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites

Journal of medicinal chemistry, 2023-10, Vol.66 (19), p.13452-13480

2023

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Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.781-791

2022

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Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease

International journal of pharmaceutics, 2014-09, Vol.472 (1-2), p.110-117

2014

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Antibacterial, Trichomonacidal, and Cytotoxic Activities of Pleopeltis crassinervata Extracts

Pharmaceutics, 2024-05, Vol.16 (5), p.624

2024

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In vitro phenotypic screening of 7-chloro-4-amino(oxy)quinoline derivatives as putative anti-Trypanosoma cruzi agents

Bioorganic & medicinal chemistry letters, 2014-02, Vol.24 (4), p.1209-1213

2014

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Synthesis and antimalarial activity of new heterocyclic hybrids based on chloroquine and thiazolidinone scaffolds

Bioorganic & medicinal chemistry, 2011-08, Vol.19 (15), p.4562-4573

2011

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New Imidazole-Based Compounds Active Against Trypanosoma cruzi

Combinatorial chemistry & high throughput screening, 2017-01, Vol.20 (1), p.20-24

2017

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Development of resazurin microtiter assay for drug sensibility testing of Trypanosoma cruzi epimastigotes

Parasitology research (1987), 2006-07, Vol.99 (2), p.103-107

2006

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Sequestration of host-CD59 as potential immune evasion strategy of Trichomonas vaginalis

Acta tropica, 2015-09, Vol.149, p.1-7

2015

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Trypanocidal Activity of Long Chain Diamines and Aminoalcohols

Molecules (Basel, Switzerland), 2015-06, Vol.20 (6), p.11554-11568

2015

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A novel non-stochastic quadratic fingerprints-based approach for the ‘in silico’ discovery of new antitrypanosomal compounds

Bioorganic & medicinal chemistry, 2005-11, Vol.13 (22), p.6264-6275

2005

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New antitrichomonal drug-like chemicals selected by bond (edge)-based TOMOCOMD-CARDD descriptors

Journal of biomolecular screening, 2008-09, Vol.13 (8), p.785-794

2008

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In vitro trichomonacidal activity and preliminary in silico chemometric studies of 5-nitroindazolin-3-one and 3-alkoxy-5-nitroindazole derivatives

Parasitology, 2016-01, Vol.143 (1), p.34-40

2016

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Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2‐Benzyl‐5‐nitroindazole‐Derived Amines

ChemMedChem, 2018-06, Vol.13 (12), p.1246-1259

2018

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Biological characterization of a beta-galactosidase expressing clone of Trypanosoma cruzi CL strain

Memórias do Instituto Oswaldo Cruz, 2002-12, Vol.97 (8), p.1101-1105

2002

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2H-Benzimidazole 1,3-Dioxide Derivatives: A New Family of Water-Soluble Anti-Trypanosomatid Agents

Journal of medicinal chemistry, 2006-06, Vol.49 (11), p.3215-3224

2006

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Recent developments in the design and synthesis of hybrid molecules based on aminoquinoline ring and their antiplasmodial evaluation

European journal of medicinal chemistry, 2009-08, Vol.44 (8), p.3091-3113

2009

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In Vitro and in Vivo Anti- Trypanosoma cruzi Activity of a Novel Nitro-derivative

Memórias do Instituto Oswaldo Cruz, 2002-06, Vol.97 (4), p.553-557

2002

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5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents

Acta tropica, 2022-10, Vol.234, p.106607-106607, Article 106607

2022

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Synthesis and Antiparasitic Properties of New 4-N-Benzylamino-4-Hetarylbut-1-enes

Archiv der Pharmazie (Weinheim), 2005-01, Vol.338 (1), p.32-37

2005

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Recent developments in the design and synthesis of hybrid molecules basedon aminoquinoline ring and their antiplasmodial evaluation

European journal of medicinal chemistry, 2009-08, Vol.44 (8), p.3091-3113

2009

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Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi

Parasitology research (1987), 2018-11, Vol.117 (11), p.3367-3380

2018

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Identification In Silico and In Vitro of Novel Trypanosomicidal Drug-Like Compounds

Chemical biology & drug design, 2012-07, Vol.80 (1), p.38-45

2012

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Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles

Bioorganic & medicinal chemistry letters, 2021-04, Vol.37, p.127843-127843, Article 127843

2021

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Determination of internal transcribed spacer regions (ITS) in Trichomonas vaginalis isolates and differentiation among Trichomonas species

Parasitology international, 2014-04, Vol.63 (2), p.427-431

2014

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Synthesis and Biophysical and Biological Studies of N‑Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites

Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis

Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease

Antibacterial, Trichomonacidal, and Cytotoxic Activities of Pleopeltis crassinervata Extracts

In vitro phenotypic screening of 7-chloro-4-amino(oxy)quinoline derivatives as putative anti-Trypanosoma cruzi agents

Synthesis and antimalarial activity of new heterocyclic hybrids based on chloroquine and thiazolidinone scaffolds

New Imidazole-Based Compounds Active Against Trypanosoma cruzi

Development of resazurin microtiter assay for drug sensibility testing of Trypanosoma cruzi epimastigotes

Sequestration of host-CD59 as potential immune evasion strategy of Trichomonas vaginalis

Trypanocidal Activity of Long Chain Diamines and Aminoalcohols

A novel non-stochastic quadratic fingerprints-based approach for the ‘in silico’ discovery of new antitrypanosomal compounds

New antitrichomonal drug-like chemicals selected by bond (edge)-based TOMOCOMD-CARDD descriptors

In vitro trichomonacidal activity and preliminary in silico chemometric studies of 5-nitroindazolin-3-one and 3-alkoxy-5-nitroindazole derivatives

Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2‐Benzyl‐5‐nitroindazole‐Derived Amines

Biological characterization of a beta-galactosidase expressing clone of Trypanosoma cruzi CL strain

2H-Benzimidazole 1,3-Dioxide Derivatives: A New Family of Water-Soluble Anti-Trypanosomatid Agents

Recent developments in the design and synthesis of hybrid molecules based on aminoquinoline ring and their antiplasmodial evaluation

In Vitro and in Vivo Anti- Trypanosoma cruzi Activity of a Novel Nitro-derivative

5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents

Synthesis and Antiparasitic Properties of New 4-N-Benzylamino-4-Hetarylbut-1-enes

Recent developments in the design and synthesis of hybrid molecules basedon aminoquinoline ring and their antiplasmodial evaluation

Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi

Identification In Silico and In Vitro of Novel Trypanosomicidal Drug-Like Compounds

Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles

Determination of internal transcribed spacer regions (ITS) in Trichomonas vaginalis isolates and differentiation among Trichomonas species

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