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Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate

Nature communications, 2020-01, Vol.11 (1), p.500-500, Article 500

2020

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Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology

Nature chemical biology, 2012-07, Vol.8 (8), p.683-694

2012

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Glycosidase inhibition: assessing mimicry of the transition state

Organic & biomolecular chemistry, 2010-01, Vol.8 (2), p.305-320

2010

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CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23

Nucleic acids research, 2024-04, Vol.52 (6), p.2761-2775

2024

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Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

Nature chemical biology, 2011-03, Vol.7 (3), p.174-181

2011

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Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open

Nucleic acids research, 2023-10, Vol.51 (19), p.10590-10605

2023

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Advances in understanding glycosyltransferases from a structural perspective

Current opinion in structural biology, 2014-10, Vol.28, p.131-141

Gloster, Tracey M

2014

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Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

Nature communications, 2018-08, Vol.9 (1), p.3243-12, Article 3243

2018

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How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (51), p.20889-20894

2012

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Development of inhibitors as research tools for carbohydrate-processing enzymes

Biochemical Society transactions, 2012-10, Vol.40 (5), p.913-928

Gloster, Tracey M

2012

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Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage

eLife, 2020-06, Vol.9

2020

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Sialidase and Sialyltransferase Inhibitors: Targeting Pathogenicity and Disease

Frontiers in molecular biosciences, 2021-07, Vol.8, p.705133-705133

2021

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Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars

Angewandte Chemie International Edition, 2016-11, Vol.55 (48), p.14978-14982

International ed. in English, 2016

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Exploitation of carbohydrate processing enzymes in biocatalysis

Current opinion in chemical biology, 2020-04, Vol.55, p.180-188

Gloster, Tracey M.

2020

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Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m1A22-tRNA methyltransferase TrmK

The Journal of biological chemistry, 2022-06, Vol.298 (6), p.102040-102040, Article 102040

2022

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The Enzymatic Degradation of Heparan Sulfate

Protein and peptide letters, 2017-01, Vol.24 (8), p.710

2017

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Glycosidase Inhibition: An Assessment of the Binding of 18 Putative Transition-State Mimics

Journal of the American Chemical Society, 2007-02, Vol.129 (8), p.2345-2354

2007

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Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (3), p.781-786

2012

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Total Syntheses of Casuarine and Its 6‐O‐α‐Glucoside: Complementary Inhibition towards Glycoside Hydrolases of the GH31 and GH37 Families

Chemistry : a European journal, 2009-02, Vol.15 (7), p.1627-1636

2009

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The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence

Nucleic acids research, 2021-03, Vol.49 (5), p.2777-2789

2021

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Author Correction: Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

Nature communications, 2018-09, Vol.9 (1), p.3700-1, Article 3700

2018

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Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (9), p.3065-3070

2009

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An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity

Nature (London), 2020-01, Vol.577 (7791), p.572-575

2020

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Molecular Basis for Trehalase Inhibition Revealed by the Structure of Trehalase in Complex with Potent Inhibitors

Angewandte Chemie International Edition, 2007-01, Vol.46 (22), p.4115-4119

2007

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Characterization and Three-dimensional Structures of Two Distinct Bacterial Xyloglucanases from Families GH5 and GH12

The Journal of biological chemistry, 2007-06, Vol.282 (26), p.19177-19189

2007

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Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate

Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology

Glycosidase inhibition: assessing mimicry of the transition state

CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23

Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open

Advances in understanding glycosyltransferases from a structural perspective

Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity

Development of inhibitors as research tools for carbohydrate-processing enzymes

Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage

Sialidase and Sialyltransferase Inhibitors: Targeting Pathogenicity and Disease

Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars

Exploitation of carbohydrate processing enzymes in biocatalysis

Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m1A22-tRNA methyltransferase TrmK

The Enzymatic Degradation of Heparan Sulfate

Glycosidase Inhibition: An Assessment of the Binding of 18 Putative Transition-State Mimics

Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase

Total Syntheses of Casuarine and Its 6‐O‐α‐Glucoside: Complementary Inhibition towards Glycoside Hydrolases of the GH31 and GH37 Families

The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence

Author Correction: Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function

An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity

Molecular Basis for Trehalase Inhibition Revealed by the Structure of Trehalase in Complex with Potent Inhibitors

Characterization and Three-dimensional Structures of Two Distinct Bacterial Xyloglucanases from Families GH5 and GH12

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