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Advances in understanding glycosyltransferases from a structural perspective

Current opinion in structural biology, 2014-10, Vol.28, p.131-141

Gloster, Tracey M

2014

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Exploitation of carbohydrate processing enzymes in biocatalysis

Current opinion in chemical biology, 2020-04, Vol.55, p.180-188

Gloster, Tracey M.

2020

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Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate

Nature communications, 2020-01, Vol.11 (1), p.500-500, Article 500

2020

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Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology

Nature chemical biology, 2012-07, Vol.8 (8), p.683-694

2012

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Glycosidase inhibition: assessing mimicry of the transition state

Organic & biomolecular chemistry, 2010-01, Vol.8 (2), p.305-320

2010

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CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23

Nucleic acids research, 2024-04, Vol.52 (6), p.2761-2775

2024

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The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence

Nucleic acids research, 2021-03, Vol.49 (5), p.2777-2789

2021

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An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity

Nature (London), 2020-01, Vol.577 (7791), p.572-575

2020

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Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open

Nucleic acids research, 2023-10, Vol.51 (19), p.10590-10605

2023

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Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

Nature chemical biology, 2011-03, Vol.7 (3), p.174-181

2011

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Metabolic Inhibitors of O‐GlcNAc Transferase That Act In Vivo Implicate Decreased O‐GlcNAc Levels in Leptin‐Mediated Nutrient Sensing

Angewandte Chemie International Edition, 2018-06, Vol.57 (26), p.7644-7648

International ed. in English, 2018

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Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

Nature communications, 2018-08, Vol.9 (1), p.3243-12, Article 3243

2018

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Development of inhibitors as research tools for carbohydrate-processing enzymes

Biochemical Society transactions, 2012-10, Vol.40 (5), p.913-928

Gloster, Tracey M

2012

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How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (51), p.20889-20894

2012

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Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage

eLife, 2020-06, Vol.9

2020

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Insights into O-Linked N-Acetylglucosamine ([0-9]O-GlcNAc) Processing and Dynamics through Kinetic Analysis of O-GlcNAc Transferase and O-GlcNAcase Activity on Protein Substrates

The Journal of biological chemistry, 2012-05, Vol.287 (19), p.15395-15408

2012

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Structural snapshots of the reaction coordinate for O-GlcNAc transferase

Nature chemical biology, 2012-12, Vol.8 (12), p.966-968

2012

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Sialidase and Sialyltransferase Inhibitors: Targeting Pathogenicity and Disease

Frontiers in molecular biosciences, 2021-07, Vol.8, p.705133-705133

2021

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Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars

Angewandte Chemie International Edition, 2016-11, Vol.55 (48), p.14978-14982

International ed. in English, 2016

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Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m1A22-tRNA methyltransferase TrmK

The Journal of biological chemistry, 2022-06, Vol.298 (6), p.102040-102040, Article 102040

2022

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Recent structural insights into the expanding world of carbohydrate-active enzymes

Current opinion in structural biology, 2005-12, Vol.15 (6), p.637-645

2005

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The Enzymatic Degradation of Heparan Sulfate

Protein and peptide letters, 2017-01, Vol.24 (8), p.710

2017

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Linear Eyring Plots Conceal a Change in the Rate-Limiting Step in an Enzyme Reaction

Biochemistry (Easton), 2018-12, Vol.57 (49), p.6757-6761

2018

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cazy_webscraper: local compilation and interrogation of comprehensive CAZyme datasets

Microbial genomics, 2023-08, Vol.9 (8)

2023

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Glycosidase Inhibition: An Assessment of the Binding of 18 Putative Transition-State Mimics

Journal of the American Chemical Society, 2007-02, Vol.129 (8), p.2345-2354

2007

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Advances in understanding glycosyltransferases from a structural perspective

Exploitation of carbohydrate processing enzymes in biocatalysis

Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate

Developing inhibitors of glycan processing enzymes as tools for enabling glycobiology

Glycosidase inhibition: assessing mimicry of the transition state

CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23

The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence

An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity

Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open

Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

Metabolic Inhibitors of O‐GlcNAc Transferase That Act In Vivo Implicate Decreased O‐GlcNAc Levels in Leptin‐Mediated Nutrient Sensing

Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

Development of inhibitors as research tools for carbohydrate-processing enzymes

How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity

Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage

Insights into O-Linked N-Acetylglucosamine ([0-9]O-GlcNAc) Processing and Dynamics through Kinetic Analysis of O-GlcNAc Transferase and O-GlcNAcase Activity on Protein Substrates

Structural snapshots of the reaction coordinate for O-GlcNAc transferase

Sialidase and Sialyltransferase Inhibitors: Targeting Pathogenicity and Disease

Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars

Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m1A22-tRNA methyltransferase TrmK

Recent structural insights into the expanding world of carbohydrate-active enzymes

The Enzymatic Degradation of Heparan Sulfate

Linear Eyring Plots Conceal a Change in the Rate-Limiting Step in an Enzyme Reaction

cazy_webscraper: local compilation and interrogation of comprehensive CAZyme datasets

Glycosidase Inhibition: An Assessment of the Binding of 18 Putative Transition-State Mimics

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