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Structural essentials for β-N-acetylhexosaminidase inhibition by amides of prolines, pipecolic and azetidine carboxylic acids

Organic & biomolecular chemistry, 2016-01, Vol.14 (44), p.10371-10385

2016

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Structural essentials for β-N-acetylhexosaminidase inhibition by amides of prolines, pipecolic and azetidine carboxylic acidsElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ob01549b

2016-11

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Short and Sweet: D-Glucose to L-Glucose and L-Glucuronic Acid

Angewandte Chemie International Edition, 2014-01, Vol.53 (4), p.1160-1162

International ed. in English, 2014

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Scalable Syntheses of Both Enantiomers of DNJNAc and DGJNAc from Glucuronolactone: The Effect of N-Alkylation on Hexosaminidase Inhibition

Chemistry : a European journal, 2012-07, Vol.18 (30), p.9341-9359

2012

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Nine of 16 Stereoisomeric Polyhydroxylated Proline Amides Are Potent β‑N‑Acetylhexosaminidase Inhibitors

Journal of organic chemistry, 2014-04, Vol.79 (8), p.3398-3409

2014

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3-Hydroxyazetidine Carboxylic Acids: Non-Proteinogenic Amino Acids for Medicinal Chemists

ChemMedChem, 2013-04, Vol.8 (4), p.658-666

2013

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Synthesis from d‑Altrose of (5R,6R,7R,8S)‑5,7-Dihydroxy-8-hydroxymethylconidine and 2,4-Dideoxy-2,4-imino‑d‑glucitol, Azetidine Analogues of Swainsonine and 1,4-Dideoxy-1,4-imino‑d‑mannitol

Organic letters, 2012-08, Vol.14 (16), p.4174-4177

2012

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Synthesis of the enantiomers of XYLNAc and LYXNAc: comparison of β-N-acetylhexosaminidase inhibition by the 8 stereoisomers of 2-N-acetylamino-1,2,4-trideoxy-1,4-iminopentitols

Organic & biomolecular chemistry, 2014-06, Vol.12 (23), p.3932-3943

2014

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An approach to 8 stereoisomers of homonojirimycin from d-glucose via kinetic & thermodynamic azido-γ-lactones

Organic & biomolecular chemistry, 2013-10, Vol.11 (40), p.6886

2013

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Synthesis of 2-acetamido-1,2-dideoxy- d- galacto-nojirimycin [DGJNAc] from d-glucuronolactone: the first sub-micromolar inhibitor of α- N-acetylgalactosaminidases

Tetrahedron letters, 2010-04, Vol.51 (17), p.2222-2224

2010

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Synthesis of the enantiomers of XYLNAc and LYXNAc: comparison of β-N-acetylhexosaminidase inhibition by the 8 stereoisomers of 2-N-acetylamino-1,2,4-trideoxy-1,4-iminopentitolsElectronic supplementary information (ESI) available: NMR spectra for 20-23, 29-33, 36 and 40-46. See DOI: 10.1039/c4ob00097h

2014-05

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Short and sweet: (D)-glucose to (L)-glucose and (L)-glucuronic acid

Angewandte Chemie International Edition, 2014-01, Vol.53 (4), p.1160-1162

2014

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Kurz und knapp: L‐Glucose und L‐Glucuronsäure aus D‐Glucose

Angewandte Chemie, 2014-01, Vol.126 (4), p.1179-1182

2014

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Short and Sweet: D-Glucose to L-Glucuronic Acid and L-Glucose

Angewandte Chemie, 2014-01, Vol.126 (4), p.1179-1182

2014

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An approach to 8 stereoisomers of homonojirimycin from (D)-glucose via kinetic & thermodynamic azido-γ-lactones

Organic & biomolecular chemistry, 2013-09, Vol.11 (40), p.6886-6899

2013

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2-Acetamido- N -benzyl-1,4-imino-1,2,4-trideoxy- L -xylitol ( N -benzyl- L -XYLNAc)

Acta crystallographica. Section E, Structure reports online, 2010-05, Vol.66 (5), p.o1147-o1148

2010

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2-Acetamido-N-benzyl-1,4-imino-1,2,4-tride-oxy-l-xylitol (N-benzyl-l-XYLNAc)

Acta crystallographica. Section E, Structure reports online, 2010-04, Vol.66 (Pt 5), p.o1147-o1148

2010

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1,2:3,4-Di- O -isopropylidene-β- D -psicofuranose

Acta crystallographica. Section E, Structure reports online, 2005-09, Vol.61 (9), p.o2949-o2951

2005

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1,2:3,4-Di- O -isopropylidene-α- D -tagatofuranose

Acta crystallographica. Section E, Structure reports online, 2005-09, Vol.61 (9), p.o2891-o2893

2005

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Isopropyl 2,5-anhydro-3,4-di- O - tert -butyldiphenylsilyl- L -ribonate

Acta crystallographica. Section E, Structure reports online, 2005-08, Vol.61 (8), p.o2724-o2726

2005

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Isopropyl 2,5‐anhydro‐3,4‐di‐O‐tert‐butyldiphenylsilyl‐l‐ribonate

Acta crystallographica. Section E, Structure reports online, 2005-08, Vol.61 (8), p.o2724-o2726

2005

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1,2:3,4‐Di‐O‐isopropylidene‐α‐d‐tagatofuranose

Acta crystallographica. Section E, Structure reports online, 2005-09, Vol.61 (9), p.o2891-o2893

2005

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1,2:3,4‐Di‐O‐isopropylidene‐β‐d‐psicofuranose

Acta crystallographica. Section E, Structure reports online, 2005-09, Vol.61 (9), p.o2949-o2951

2005

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Structural essentials for β-N-acetylhexosaminidase inhibition by amides of prolines, pipecolic and azetidine carboxylic acids

Structural essentials for β-N-acetylhexosaminidase inhibition by amides of prolines, pipecolic and azetidine carboxylic acidsElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ob01549b

Short and Sweet: D-Glucose to L-Glucose and L-Glucuronic Acid

Scalable Syntheses of Both Enantiomers of DNJNAc and DGJNAc from Glucuronolactone: The Effect of N-Alkylation on Hexosaminidase Inhibition

Nine of 16 Stereoisomeric Polyhydroxylated Proline Amides Are Potent β‑N‑Acetylhexosaminidase Inhibitors

3-Hydroxyazetidine Carboxylic Acids: Non-Proteinogenic Amino Acids for Medicinal Chemists

Synthesis from d‑Altrose of (5R,6R,7R,8S)‑5,7-Dihydroxy-8-hydroxymethylconidine and 2,4-Dideoxy-2,4-imino‑d‑glucitol, Azetidine Analogues of Swainsonine and 1,4-Dideoxy-1,4-imino‑d‑mannitol

Synthesis of the enantiomers of XYLNAc and LYXNAc: comparison of β-N-acetylhexosaminidase inhibition by the 8 stereoisomers of 2-N-acetylamino-1,2,4-trideoxy-1,4-iminopentitols

An approach to 8 stereoisomers of homonojirimycin from d-glucose via kinetic & thermodynamic azido-γ-lactones

Synthesis of 2-acetamido-1,2-dideoxy- d- galacto-nojirimycin [DGJNAc] from d-glucuronolactone: the first sub-micromolar inhibitor of α- N-acetylgalactosaminidases

Short and sweet: (D)-glucose to (L)-glucose and (L)-glucuronic acid

Kurz und knapp: L‐Glucose und L‐Glucuronsäure aus D‐Glucose

Short and Sweet: D-Glucose to L-Glucuronic Acid and L-Glucose

An approach to 8 stereoisomers of homonojirimycin from (D)-glucose via kinetic & thermodynamic azido-γ-lactones

2-Acetamido- N -benzyl-1,4-imino-1,2,4-trideoxy- L -xylitol ( N -benzyl- L -XYLNAc)

2-Acetamido-N-benzyl-1,4-imino-1,2,4-tride-oxy-l-xylitol (N-benzyl-l-XYLNAc)

1,2:3,4-Di- O -isopropylidene-β- D -psicofuranose

1,2:3,4-Di- O -isopropylidene-α- D -tagatofuranose

Isopropyl 2,5-anhydro-3,4-di- O - tert -butyldiphenylsilyl- L -ribonate

Isopropyl 2,5‐anhydro‐3,4‐di‐O‐tert‐butyldiphenylsilyl‐l‐ribonate

1,2:3,4‐Di‐O‐isopropylidene‐α‐d‐tagatofuranose

1,2:3,4‐Di‐O‐isopropylidene‐β‐d‐psicofuranose

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