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Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

Nature, 2005-03, Vol.434 (7033), p.644-648

2005

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Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage

BMC musculoskeletal disorders, 2011-07, Vol.12 (1), p.164-164, Article 164

2011

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LXR modulation blocks prostaglandin E₂ production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (8), p.3734-3739

2010

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In vivo osteoarthritis target validation utilizing genetically-modified mice

Current drug targets, 2007-02, Vol.8 (2), p.367

Glasson, Sonya S

2007

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Repair of articular cartilage defects one year after treatment with recombinant human bone morphogenetic protein-2 (rhBMP-2)

Journal of bone and joint surgery. American volume, 2000-02, Vol.82 (2), p.151

2000

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Double‐knockout of ADAMTS‐4 and ADAMTS‐5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis

Arthritis and rheumatism, 2007-11, Vol.56 (11), p.3670-3674

2007

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Chondral Defect Repair after the Microfracture Procedure: A Nonhuman Primate Model

The American journal of sports medicine, 2005-05, Vol.33 (5), p.680-685

2005

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The influence of enrichment devices on development of osteoarthritis in a surgically induced murine model

ILAR journal, 2008-09, Vol.49 (4), p.23-30

2008

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Characterization of and osteoarthritis susceptibility in ADAMTS‐4–knockout mice

Arthritis and rheumatism, 2004-08, Vol.50 (8), p.2547-2558

2004

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Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

Nature (London), 2007-03, Vol.446 (7131), p.102-102

2007

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Mapping pathogenesis of arthritis through small animal models

Rheumatology (Oxford, England), 2012-11, Vol.51 (11), p.1931-1941

2012

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Prevention of cartilage degeneration in a rat model of osteoarthritis by intraarticular treatment with recombinant lubricin

Arthritis and rheumatism, 2009-03, Vol.60 (3), p.840-847

2009

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LXR modulation blocks prostaglandin E 2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (8), p.3734-3739

2010

Volltextzugriff (PDF)

LXR modulation blocks prostaglandin E^sub 2^ production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (8), p.3734

2010

Volltextzugriff (PDF)

LXR modulation blocks prostaglandin Eâ production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

Proceedings of the National Academy of Sciences - PNAS, 2010, Vol.107 (8), p.3734-3739

2010

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LXR modulation blocks prostaglandin E sub(2) production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (8), p.3734-3739

2010

Volltextzugriff (PDF)

Chondral Defect Repair After the Microfracture Procedure

The American journal of sports medicine, 2005-05, Vol.33 (5), p.680

2005

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Erratum: Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

Nature (London), 2007-03, Vol.446 (7131), p.102-102

2007

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Spontaneous Osteoarthritis in Dunkin Hartley Guinea Pigs: Histologic, Radiologic, and Biochemical Changes

Comparative medicine, 1997-12, Vol.47 (6), p.598-601

1997

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Blotchy mice: a model of osteoarthritis associated with a metabolic defect

Osteoarthritis and cartilage, 1996-09, Vol.4 (3), p.209-212

1996

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Spontaneous osteoarthritis in Dunkin Hartley guinea pigs: histologic, radiologic, and biochemical changes

Laboratory animal science (Chicago), 1997-12, Vol.47 (6), p.598

1997

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Immortalized mouse articular cartilage cell lines retain chondrocyte phenotype and respond to both anabolic factor BMP-2 and pro-inflammatory factor IL-1

Journal of cellular physiology, 2008-04, Vol.215 (1), p.68-76

2008

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In Vitro–In Vivo Correlation on Delivery of Drug Candidates to Articular Cartilage

Pharmaceutical research, 2008-07, Vol.25 (7), p.1641-1646

2008

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Immortalized cell lines from mouse xiphisternum preserve chondrocyte phenotype

Journal of cellular physiology, 2006-11, Vol.209 (2), p.551-559

2006

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Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis

Arthritis and rheumatism, 2007-08, Vol.56 (8), p.2663-2673

2007

Volltextzugriff (PDF)

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Cartilage, Articular - Pathology
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Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage

LXR modulation blocks prostaglandin E₂ production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

In vivo osteoarthritis target validation utilizing genetically-modified mice

Repair of articular cartilage defects one year after treatment with recombinant human bone morphogenetic protein-2 (rhBMP-2)

Double‐knockout of ADAMTS‐4 and ADAMTS‐5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis

Chondral Defect Repair after the Microfracture Procedure: A Nonhuman Primate Model

The influence of enrichment devices on development of osteoarthritis in a surgically induced murine model

Characterization of and osteoarthritis susceptibility in ADAMTS‐4–knockout mice

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

Mapping pathogenesis of arthritis through small animal models

Prevention of cartilage degeneration in a rat model of osteoarthritis by intraarticular treatment with recombinant lubricin

LXR modulation blocks prostaglandin E 2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

LXR modulation blocks prostaglandin E^sub 2^ production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

LXR modulation blocks prostaglandin Eâ production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

LXR modulation blocks prostaglandin E sub(2) production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

Chondral Defect Repair After the Microfracture Procedure

Erratum: Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

Spontaneous Osteoarthritis in Dunkin Hartley Guinea Pigs: Histologic, Radiologic, and Biochemical Changes

Blotchy mice: a model of osteoarthritis associated with a metabolic defect

Spontaneous osteoarthritis in Dunkin Hartley guinea pigs: histologic, radiologic, and biochemical changes

Immortalized mouse articular cartilage cell lines retain chondrocyte phenotype and respond to both anabolic factor BMP-2 and pro-inflammatory factor IL-1

In Vitro–In Vivo Correlation on Delivery of Drug Candidates to Articular Cartilage

Immortalized cell lines from mouse xiphisternum preserve chondrocyte phenotype

Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis

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