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Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways

Cell metabolism, 2012-08, Vol.16 (2), p.153-166

2012

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Senescent cells damage the body throughout life

Nature (London), 2023-01, Vol.613 (7942), p.30-31

Glass, David J

2023

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Signaling pathways controlling skeletal muscle mass

Critical reviews in biochemistry and molecular biology, 2014-01, Vol.49 (1), p.59-68

2014

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PI3 kinase regulation of skeletal muscle hypertrophy and atrophy

Current topics in microbiology and immunology, 2010-01, Vol.346, p.267

Glass, David J

2010

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A Long Non-coding RNA, LncMyoD, Regulates Skeletal Muscle Differentiation by Blocking IMP2-Mediated mRNA Translation

Developmental cell, 2015-07, Vol.34 (2), p.181-191

2015

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TORC1 inhibition enhances immune function and reduces infections in the elderly

Science translational medicine, 2018-07, Vol.10 (449)

2018

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Elevated GDF11 Is a Risk Factor for Age-Related Frailty and Disease in Humans

Cell metabolism, 2016-07, Vol.24 (1), p.7-8

Glass, David J.

2016

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GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration

Cell metabolism, 2015-07, Vol.22 (1), p.164-174

2015

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The role of GDF11 in aging and skeletal muscle, cardiac and bone homeostasis

Critical reviews in biochemistry and molecular biology, 2019-03, Vol.54 (2), p.174-183

2019

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Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

American Journal of Physiology: Cell Physiology, 2009-06, Vol.296 (6), p.C1258-C1270

2009

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Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple Tissues

Cell reports (Cambridge), 2019-09, Vol.28 (12), p.3263-3273.e3

2019

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ATP Citrate Lyase Improves Mitochondrial Function in Skeletal Muscle

Cell metabolism, 2015-06, Vol.21 (6), p.868-876

2015

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An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy

Molecular and Cellular Biology, 2014-02, Vol.34 (4), p.606-618

2014

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The SCF-Fbxo40 Complex Induces IRS1 Ubiquitination in Skeletal Muscle, Limiting IGF1 Signaling

Developmental cell, 2011-11, Vol.21 (5), p.835-847

2011

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Activin type II receptor signaling in cardiac aging and heart failure

Science translational medicine, 2019-03, Vol.11 (482)

2019

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mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4

Nature communications, 2019-07, Vol.10 (1), p.3187-16, Article 3187

2019

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HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70

Cell reports (Cambridge), 2019-10, Vol.29 (3), p.749-763.e12

2019

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Genomic and Proteomic Profiling Reveals Reduced Mitochondrial Function and Disruption of the Neuromuscular Junction Driving Rat Sarcopenia

Molecular and Cellular Biology, 2013-01, Vol.33 (2), p.194-212

2013

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Adult Brain Serotonin Deficiency Causes Hyperactivity, Circadian Disruption, and Elimination of Siestas

The Journal of neuroscience, 2016-09, Vol.36 (38), p.9828-9842

2016

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Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space

Scientific reports, 2019-06, Vol.9 (1), p.9397-11, Article 9397

2019

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Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins

The Journal of clinical investigation, 2022-01, Vol.132 (1), p.1-1

2022

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An HMGA2-IGF2BP2 Axis Regulates Myoblast Proliferation and Myogenesis

Developmental cell, 2012-12, Vol.23 (6), p.1176-1188

2012

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Blockade of Metallothioneins 1 and 2 Increases Skeletal Muscle Mass and Strength

Molecular and cellular biology, 2017-03, Vol.37 (5)

2017

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The IGF-1/PI3K/Akt Pathway Prevents Expression of Muscle Atrophy-Induced Ubiquitin Ligases by Inhibiting FOXO Transcription Factors

Molecular cell, 2004-05, Vol.14 (3), p.395-403

2004

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TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice

The Journal of cell biology, 2010-03, Vol.188 (6), p.833-849

2010

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Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways

Senescent cells damage the body throughout life

Signaling pathways controlling skeletal muscle mass

PI3 kinase regulation of skeletal muscle hypertrophy and atrophy

A Long Non-coding RNA, LncMyoD, Regulates Skeletal Muscle Differentiation by Blocking IMP2-Mediated mRNA Translation

TORC1 inhibition enhances immune function and reduces infections in the elderly

Elevated GDF11 Is a Risk Factor for Age-Related Frailty and Disease in Humans

GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration

The role of GDF11 in aging and skeletal muscle, cardiac and bone homeostasis

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple Tissues

ATP Citrate Lyase Improves Mitochondrial Function in Skeletal Muscle

An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy

The SCF-Fbxo40 Complex Induces IRS1 Ubiquitination in Skeletal Muscle, Limiting IGF1 Signaling

Activin type II receptor signaling in cardiac aging and heart failure

mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4

HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70

Genomic and Proteomic Profiling Reveals Reduced Mitochondrial Function and Disruption of the Neuromuscular Junction Driving Rat Sarcopenia

Adult Brain Serotonin Deficiency Causes Hyperactivity, Circadian Disruption, and Elimination of Siestas

Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins

An HMGA2-IGF2BP2 Axis Regulates Myoblast Proliferation and Myogenesis

Blockade of Metallothioneins 1 and 2 Increases Skeletal Muscle Mass and Strength

The IGF-1/PI3K/Akt Pathway Prevents Expression of Muscle Atrophy-Induced Ubiquitin Ligases by Inhibiting FOXO Transcription Factors

TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice

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